Q15034: Probable E3 ubiquitin-protein ligase HERC3

General Information

Protein names	- Probable E3 ubiquitin-protein ligase HERC3 - 2.3.2.26 - HECT domain and RCC1-like domain-containing protein 3 - HECT-type E3 ubiquitin transferase HERC3
Gene names	HERC3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15034

3 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL
        70         80         90        100        110        120
NTKGQLGHER EGNKPEQIGA LADQHIIHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT
       130        140        150        160        170        180
TEDSVAVPRL IQKLNQQTIL QVSCGNWHCL ALAADGQFFT WGKNSHGQLG LGKEFPSQAS
       190        200        210        220        230        240
PQRVRSLEGI PLAQVAAGGA HSFALSLSGA VFGWGMNNAG QLGLSDEKDR ESPCHVKLLR
       250        260        270        280        290        300
TQKVVYISCG EEHTAVLTKS GGVFTFGAGS CGQLGHDSMN DEVNPRRVLE LMGSEVTQIA
       310        320        330        340        350        360
CGRQHTLAFV PSSGLIYAFG CGARGQLGTG HTCNVKCPSP VKGYWAAHSG QLSARADRFK
       370        380        390        400        410        420
YHIVKQIFSG GDQTFVLCSK YENYSPAVDF RTMNQAHYTS LINDETIAVW RQKLSEHNNA
       430        440        450        460        470        480
NTINGVVQIL SSAACWNGSF LEKKIDEHFK TSPKIPGIDL NSTRVLFEKL MNSQHSMILE
       490        500        510        520        530        540
QILNSFESCL IPQLSSSPPD VEAMRIYLIL PEFPLLQDSK YYITLTIPLA MAILRLDTNP
       550        560        570        580        590        600
SKVLDNWWSQ VCPKYFMKLV NLYKGAVLYL LRGRKTFLIP VLFNNYITAA LKLLEKLYKV
       610        620        630        640        650        660
NLKVKHVEYD TFYIPEISNL VDIQEDYLMW FLHQAGMKAR PSIIQDTVTL CSYPFIFDAQ
       670        680        690        700        710        720
AKTKMLQTDA ELQMQVAVNG ANLQNVFMLL TLEPLLARSP FLVLHVRRNN LVGDALRELS
       730        740        750        760        770        780
IHSDIDLKKP LKVIFDGEEA VDAGGVTKEF FLLLLKELLN PIYGMFTYYQ DSNLLWFSDT
       790        800        810        820        830        840
CFVEHNWFHL IGITCGLAIY NSTVVDLHFP LALYKKLLNV KPGLEDLKEL SPTEGRSLQE
       850        860        870        880        890        900
LLDYPGEDVE ETFCLNFTIC RESYGVIEQK KLIPGGDNVT VCKDNRQEFV DAYVNYVFQI
       910        920        930        940        950        960
SVHEWYTAFS SGFLKVCGGK VLELFQPSEL RAMMVGNSNY NWEELEETAI YKGDYSATHP
       970        980        990       1000       1010       1020
TVKLFWETFH EFPLEKKKKF LLFLTGSDRI PIYGMASLQI VIQSTASGEE YLPVAHTCYN
      1030       1040       1050
LLDLPKYSSK EILSARLTQA LDNYEGFSLA

Isoforms

- Isoform 2 of Probable E3 ubiquitin-protein ligase HERC3

Sequence View

        10         20         30         40         50         60
MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL
        70         80         90        100        110        120
NTKGQLGHER EGNKPEQIGA LADQHIIHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT
       130        140        150        160        170        180
TEDSVAVPRL IQKLNQQTIL QVSCGNWHCL ALAADGQFFT WGKNSHGQLG LGKEFPSQAS
       190        200        210        220        230        240
PQRVRSLEGI PLAQVAAGGA HSFALSLSGA VFGWGMNNAG QLGLSDEKDR ESPCHVKLLR
       250        260        270        280        290        300
TQKVVYISCG EEHTAVLTKS GGVFTFGAGS CGQLGHDSMN DEVNPRRVLE LMGSEVTQIA
       310        320        330        340        350        360
CGRQHTLAFV PSSGLIYAFG CGARGQLGTG HTCNVKCPSP VKGYWAAHSG QLSARADRFK
       370        380        390        400        410        420
YHIVKQIFSG GDQTFVLCSK YENYSPAVDF RTMNQAHYTS LINDETIAVW RQKLSEHNNA
       430        440        450        460        470        480
NTINGVVQIL SSAACWNGSF LEKKIDEHFK TSPKIPGIDL NSTRVLFEKL MNSQHSMILE
       490        500        510        520        530        540
QILNSFESCL IPQLSSSPPD VEAMRIYLIL PEFPLLQDSK YYITLTIPLA MAILRLDTNP
       550        560        570        580        590        600
SKVLDNWWSQ VCPKYFMKLV NLYKGAVLYL LRGRKTFLIP VLFNNYITAA LKLLEKLYKV
       610        620        630        640        650        660
NLKVKHVEYD TFYIPEISNL VDIQEDYLMW FLHQAGMKAR PSIIQDTVTL CSYPFIFDAQ
       670        680        690        700        710        720
AKTKMLQTDA ELQMQVAVNG ANLQNVFMLL TLEPLLARSP FLVLHVRRNN LVGDALRELS
       730        740        750        760        770        780
IHSDIDLKKP LKVIFDGEEA VDAGGVTKEF FLLLLKELLN PIYGMFTYYQ DSNLLWFSDT
       790        800        810        820        830        840
CFVEHNWFHL IGITCGLAIY NSTVVDLHFP LALYKKLLNV KPGLEDLKEL SPTEGRSLQE
       850        860        870        880        890        900
LLDYPGEDVE ETFCLNFTIC RESYGVIEQK KLIPGGDNVT VCKDNRQEFV DAYVNYVFQI
       910        920        930        940        950        960
SVHEWYTAFS SGFLKVCGGK VLELFQPSEL RAMMVGNSNY NWEELEETAI YKGDYSATHP
       970        980        990       1000       1010       1020
TVKLFWETFH EFPLEKKKKF LLFLTGSDRI PIYGMASLQI VIQSTASGEE YLPVAHTCYN
      1030       1040       1050
LLDLPKYSSK EILSARLTQA LDNYEGFSLA

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15034-1-unknown	MLCWGY...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15034-557-unknown	MKLVNL...	557	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441703
Q15034-600-unknown	VNLKVK...	600	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000421021

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KPEQIG	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000424786
...ACGESH	94	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410029
...SVAVPR	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389991
...VPRLIQ	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405863
...GLSDEK	227	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406210
...VCKDNR	885	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000421021
...GFSLA	1050	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q15034: Probable E3 ubiquitin-protein ligase HERC3

General Information

3

N-termini

7

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates