TopFIND 4.0

Q15223: Nectin-1

General Information

Protein names
- Nectin-1
- Herpes virus entry mediator C
- Herpesvirus entry mediator C
- HveC
- Herpesvirus Ig-like receptor
- HIgR
- Nectin cell adhesion molecule 1 {ECO:0000312|HGNC:HGNC:9706}
- Poliovirus receptor-related protein 1
- CD111
Gene names PVRL1
Organism Homo sapiens
Protease Family
Protease ID I43.001
Chromosome location
UniProt ID Q15223

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MARMGLAGAA GRWWGLALGL TAFFLPGVHS QVVQVNDSMY GFIGTDVVLH CSFANPLPSV 
        70         80         90        100        110        120 
KITQVTWQKS TNGSKQNVAI YNPSMGVSVL APYRERVEFL RPSFTDGTIR LSRLELEDEG 
       130        140        150        160        170        180 
VYICEFATFP TGNRESQLNL TVMAKPTNWI EGTQAVLRAK KGQDDKVLVA TCTSANGKPP 
       190        200        210        220        230        240 
SVVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH QQSLACIVNY HMDRFKESLT 
       250        260        270        280        290        300 
LNVQYEPEVT IEGFDGNWYL QRMDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL 
       310        320        330        340        350        360 
FFKGPINYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP SPPEHGRRAG PVPTAIIGGV 
       370        380        390        400        410        420 
AGSILLVLIV VGGIVVALRR RRHTFKGDYS TKKHVYGNGY SKAGIPQHHP PMAQNLQYPD 
       430        440        450        460        470        480 
DSDDEKKAGP LGGSSYEEEE EEEEGGGGGE RKVGGPHPKY DEDAKRPYFT VDEAEARQDG 
       490        500        510    
YGDRTLGYQY DPEQLDLAEN MVSQNDGSFI SKKEWYV

Isoforms

- Isoform Alpha of Nectin-1 - Isoform Gamma of Nectin-1

Sequence View

        10         20         30         40         50         60 
MARMGLAGAA GRWWGLALGL TAFFLPGVHS QVVQVNDSMY GFIGTDVVLH CSFANPLPSV 
        70         80         90        100        110        120 
KITQVTWQKS TNGSKQNVAI YNPSMGVSVL APYRERVEFL RPSFTDGTIR LSRLELEDEG 
       130        140        150        160        170        180 
VYICEFATFP TGNRESQLNL TVMAKPTNWI EGTQAVLRAK KGQDDKVLVA TCTSANGKPP 
       190        200        210        220        230        240 
SVVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH QQSLACIVNY HMDRFKESLT 
       250        260        270        280        290        300 
LNVQYEPEVT IEGFDGNWYL QRMDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL 
       310        320        330        340        350        360 
FFKGPINYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP SPPEHGRRAG PVPTAIIGGV 
       370        380        390        400        410        420 
AGSILLVLIV VGGIVVALRR RRHTFKGDYS TKKHVYGNGY SKAGIPQHHP PMAQNLQYPD 
       430        440        450        460        470        480 
DSDDEKKAGP LGGSSYEEEE EEEEGGGGGE RKVGGPHPKY DEDAKRPYFT VDEAEARQDG 
       490        500        510    
YGDRTLGYQY DPEQLDLAEN MVSQNDGSFI SKKEWYV         10         20         30         40         50         60 
MARMGLAGAA GRWWGLALGL TAFFLPGVHS QVVQVNDSMY GFIGTDVVLH CSFANPLPSV 
        70         80         90        100        110        120 
KITQVTWQKS TNGSKQNVAI YNPSMGVSVL APYRERVEFL RPSFTDGTIR LSRLELEDEG 
       130        140        150        160        170        180 
VYICEFATFP TGNRESQLNL TVMAKPTNWI EGTQAVLRAK KGQDDKVLVA TCTSANGKPP 
       190        200        210        220        230        240 
SVVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH QQSLACIVNY HMDRFKESLT 
       250        260        270        280        290        300 
LNVQYEPEVT IEGFDGNWYL QRMDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL 
       310        320        330        340        350        360 
FFKGPINYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP SPPEHGRRAG PVPTAIIGGV 
       370        380        390        400        410        420 
AGSILLVLIV VGGIVVALRR RRHTFKGDYS TKKHVYGNGY SKAGIPQHHP PMAQNLQYPD 
       430        440        450        460        470        480 
DSDDEKKAGP LGGSSYEEEE EEEEGGGGGE RKVGGPHPKY DEDAKRPYFT VDEAEARQDG 
       490        500        510    
YGDRTLGYQY DPEQLDLAEN MVSQNDGSFI SKKEWYV



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KEWYV 517 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)