TopFIND 4.0

Q15528: Mediator of RNA polymerase II transcription subunit 22

General Information

Protein names
- Mediator of RNA polymerase II transcription subunit 22
- Mediator complex subunit 22
- Surfeit locus protein 5
- Surf-5
Gene names MED22
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q15528

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAQQRALPQS KETLLQSYNK RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE 
        70         80         90        100        110        120 
MHVRAANIVR AGESLMKLVS DLKQFLILND FPSVNEAIDQ RNQQLRTLQE ECDRKLITLR 
       130        140        150        160        170        180 
DEISIDLYEL EEEYYSSSSS LCEANDLPLC EAYGRLDLDT DSADGLSAPL LASPEPSAGP 
       190        200    
LQVAAPAHSH AGGPGPTEHA 

Isoforms

- Isoform Surf5A of Mediator of RNA polymerase II transcription subunit 22

Sequence View

        10         20         30         40         50         60 
MAQQRALPQS KETLLQSYNK RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE 
        70         80         90        100        110        120 
MHVRAANIVR AGESLMKLVS DLKQFLILND FPSVNEAIDQ RNQQLRTLQE ECDRKLITLR 
       130        140        150        160        170        180 
DEISIDLYEL EEEYYSSSSS LCEANDLPLC EAYGRLDLDT DSADGLSAPL LASPEPSAGP 
       190        200    
LQVAAPAHSH AGGPGPTEHA 



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q15528-1-unknown MAQQRA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q15528-1-unknown MAQQRA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80767

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PTEHA 200 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)