TopFIND 4.0

Q15831: Serine/threonine-protein kinase STK11

General Information

Protein names
- Serine/threonine-protein kinase STK11
- 2.7.11.1
- Liver kinase B1
- LKB1
- hLKB1
- Renal carcinoma antigen NY-REN-19
Gene names STK11
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q15831

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEVVDPQQLG MFTEGELMSV GMDTFIHRID STEVIYQPRR KRAKLIGKYL MGDLLGEGSY 
        70         80         90        100        110        120 
GKVKEVLDSE TLCRRAVKIL KKKKLRRIPN GEANVKKEIQ LLRRLRHKNV IQLVDVLYNE 
       130        140        150        160        170        180 
EKQKMYMVME YCVCGMQEML DSVPEKRFPV CQAHGYFCQL IDGLEYLHSQ GIVHKDIKPG 
       190        200        210        220        230        240 
NLLLTTGGTL KISDLGVAEA LHPFAADDTC RTSQGSPAFQ PPEIANGLDT FSGFKVDIWS 
       250        260        270        280        290        300 
AGVTLYNITT GLYPFEGDNI YKLFENIGKG SYAIPGDCGP PLSDLLKGML EYEPAKRFSI 
       310        320        330        340        350        360 
RQIRQHSWFR KKHPPAEAPV PIPPSPDTKD RWRSMTVVPY LEDLHGADED EDLFDIEDDI 
       370        380        390        400        410        420 
IYTQDFTVPG QVPEEEASHN GQRRGLPKAV CMNGTEAAQL STKSRAEGRA PNPARKACSA 
       430    
SSKIRRLSAC KQQ

Isoforms

- Isoform 2 of Serine/threonine-protein kinase STK11

Sequence View

        10         20         30         40         50         60 
MEVVDPQQLG MFTEGELMSV GMDTFIHRID STEVIYQPRR KRAKLIGKYL MGDLLGEGSY 
        70         80         90        100        110        120 
GKVKEVLDSE TLCRRAVKIL KKKKLRRIPN GEANVKKEIQ LLRRLRHKNV IQLVDVLYNE 
       130        140        150        160        170        180 
EKQKMYMVME YCVCGMQEML DSVPEKRFPV CQAHGYFCQL IDGLEYLHSQ GIVHKDIKPG 
       190        200        210        220        230        240 
NLLLTTGGTL KISDLGVAEA LHPFAADDTC RTSQGSPAFQ PPEIANGLDT FSGFKVDIWS 
       250        260        270        280        290        300 
AGVTLYNITT GLYPFEGDNI YKLFENIGKG SYAIPGDCGP PLSDLLKGML EYEPAKRFSI 
       310        320        330        340        350        360 
RQIRQHSWFR KKHPPAEAPV PIPPSPDTKD RWRSMTVVPY LEDLHGADED EDLFDIEDDI 
       370        380        390        400        410        420 
IYTQDFTVPG QVPEEEASHN GQRRGLPKAV CMNGTEAAQL STKSRAEGRA PNPARKACSA 
       430    
SSKIRRLSAC KQQ



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q15831-1-unknown MEVVDP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q15831-1-unknown MEVVDP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90914

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLSACK 430 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)