Q15833: Syntaxin-binding protein 2

General Information

Protein names	- Syntaxin-binding protein 2 - Protein unc-18 homolog 2 - Unc18-2 - Protein unc-18 homolog B - Unc-18B
Gene names	STXBP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15833

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Syntaxin-binding protein 2 - Isoform 3 of Syntaxin-binding protein 2

Sequence View

        10         20         30         40         50         60
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED
        70         80         90        100        110        120
INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK AAHIFFTDTC PEPLFSELGR
       130        140        150        160        170        180
SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAEERTRQLE VLAQQIATLC
       190        200        210        220        230        240
ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV
       250        260        270        280        290        300
SPLLHELTFQ AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS
       310        320        330        340        350        360
KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS
       370        380        390        400        410        420
VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA YDKIRVLLLY ILLRNGVSEE
       430        440        450        460        470        480
NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN PGGSGTSSRL EPRERMEPTY QLSRWTPVIK
       490        500        510        520        530        540
DVMEDAVEDR LDRNLWPFVS DPAPTASSQA AVSARFGHWH KNKAGIEARA GPRLIVYVMG
       550        560        570        580        590
GVAMSEMRAA YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KALDKKLEDI ALP         10         20         30         40         50         60
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED
        70         80         90        100        110        120
INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK AAHIFFTDTC PEPLFSELGR
       130        140        150        160        170        180
SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAEERTRQLE VLAQQIATLC
       190        200        210        220        230        240
ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV
       250        260        270        280        290        300
SPLLHELTFQ AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS
       310        320        330        340        350        360
KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS
       370        380        390        400        410        420
VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA YDKIRVLLLY ILLRNGVSEE
       430        440        450        460        470        480
NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN PGGSGTSSRL EPRERMEPTY QLSRWTPVIK
       490        500        510        520        530        540
DVMEDAVEDR LDRNLWPFVS DPAPTASSQA AVSARFGHWH KNKAGIEARA GPRLIVYVMG
       550        560        570        580        590
GVAMSEMRAA YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KALDKKLEDI ALP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15833-1-acetylation	MAPSGL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15833-1-acetylation	MAPSGL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q15833-1-acetylation	MAPSGL...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163031
Q15833-1-unknown	MAPSGL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15833-1-unknown	MAPSGL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91021
Q15833-2-unknown	APSGLK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15833-2-unknown	APSGLK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q15833-2-unknown	APSGLK...	2		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163033

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DIALP	593	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...DIALP	593	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt86639

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)