Q16288: NT-3 growth factor receptor

General Information

Protein names	- NT-3 growth factor receptor - 2.7.10.1 - GP145-TrkC - Trk-C - Neurotrophic tyrosine kinase receptor type 3 - TrkC tyrosine kinase
Gene names	NTRK3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16288

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of NT-3 growth factor receptor - Isoform 3 of NT-3 growth factor receptor - Isoform 4 of NT-3 growth factor receptor - Isoform 5 of NT-3 growth factor receptor

Sequence View

        10         20         30         40         50         60
MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD GNLFPLLEGQ
        70         80         90        100        110        120
DSGNSNGNAS INITDISRNI TSIHIENWRS LHTLNAVDME LYTGLQKLTI KNSGLRSIQP
       130        140        150        160        170        180
RAFAKNPHLR YINLSSNRLT TLSWQLFQTL SLRELQLEQN FFNCSCDIRW MQLWQEQGEA
       190        200        210        220        230        240
KLNSQNLYCI NADGSQLPLF RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD
       250        260        270        280        290        300
VDWIVTGLQS INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
       310        320        330        340        350        360
VYYPPRVVSL EEPELRLEHC IEFVVRGNPP PTLHWLHNGQ PLRESKIIHV EYYQEGEISE
       370        380        390        400        410        420
GCLLFNKPTH YNNGNYTLIA KNPLGTANQT INGHFLKEPF PESTDNFILF DEVSPTPPIT
       430        440        450        460        470        480
VTHKPEEDTF GVSIAVGLAA FACVLLVVLF VMINKYGRRS KFGMKGPVAV ISGEEDSASP
       490        500        510        520        530        540
LHHINHGITT PSSLDAGPDT VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL
       550        560        570        580        590        600
KRELGEGAFG KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
       610        620        630        640        650        660
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE LGLSQMLHIA
       670        680        690        700        710        720
SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM SRDVYSTDYY RLFNPSGNDF
       730        740        750        760        770        780
CIWCEVGGHT MLPIRWMPPE SIMYRKFTTE SDVWSFGVIL WEIFTYGKQP WFQLSNTEVI
       790        800        810        820        830
ECITQGRVLE RPRVCPKEVY DVMLGCWQRE PQQRLNIKEI YKILHALGKA TPIYLDILG         10         20         30         40         50         60
MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD GNLFPLLEGQ
        70         80         90        100        110        120
DSGNSNGNAS INITDISRNI TSIHIENWRS LHTLNAVDME LYTGLQKLTI KNSGLRSIQP
       130        140        150        160        170        180
RAFAKNPHLR YINLSSNRLT TLSWQLFQTL SLRELQLEQN FFNCSCDIRW MQLWQEQGEA
       190        200        210        220        230        240
KLNSQNLYCI NADGSQLPLF RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD
       250        260        270        280        290        300
VDWIVTGLQS INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
       310        320        330        340        350        360
VYYPPRVVSL EEPELRLEHC IEFVVRGNPP PTLHWLHNGQ PLRESKIIHV EYYQEGEISE
       370        380        390        400        410        420
GCLLFNKPTH YNNGNYTLIA KNPLGTANQT INGHFLKEPF PESTDNFILF DEVSPTPPIT
       430        440        450        460        470        480
VTHKPEEDTF GVSIAVGLAA FACVLLVVLF VMINKYGRRS KFGMKGPVAV ISGEEDSASP
       490        500        510        520        530        540
LHHINHGITT PSSLDAGPDT VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL
       550        560        570        580        590        600
KRELGEGAFG KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
       610        620        630        640        650        660
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE LGLSQMLHIA
       670        680        690        700        710        720
SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM SRDVYSTDYY RLFNPSGNDF
       730        740        750        760        770        780
CIWCEVGGHT MLPIRWMPPE SIMYRKFTTE SDVWSFGVIL WEIFTYGKQP WFQLSNTEVI
       790        800        810        820        830
ECITQGRVLE RPRVCPKEVY DVMLGCWQRE PQQRLNIKEI YKILHALGKA TPIYLDILG         10         20         30         40         50         60
MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD GNLFPLLEGQ
        70         80         90        100        110        120
DSGNSNGNAS INITDISRNI TSIHIENWRS LHTLNAVDME LYTGLQKLTI KNSGLRSIQP
       130        140        150        160        170        180
RAFAKNPHLR YINLSSNRLT TLSWQLFQTL SLRELQLEQN FFNCSCDIRW MQLWQEQGEA
       190        200        210        220        230        240
KLNSQNLYCI NADGSQLPLF RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD
       250        260        270        280        290        300
VDWIVTGLQS INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
       310        320        330        340        350        360
VYYPPRVVSL EEPELRLEHC IEFVVRGNPP PTLHWLHNGQ PLRESKIIHV EYYQEGEISE
       370        380        390        400        410        420
GCLLFNKPTH YNNGNYTLIA KNPLGTANQT INGHFLKEPF PESTDNFILF DEVSPTPPIT
       430        440        450        460        470        480
VTHKPEEDTF GVSIAVGLAA FACVLLVVLF VMINKYGRRS KFGMKGPVAV ISGEEDSASP
       490        500        510        520        530        540
LHHINHGITT PSSLDAGPDT VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL
       550        560        570        580        590        600
KRELGEGAFG KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
       610        620        630        640        650        660
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE LGLSQMLHIA
       670        680        690        700        710        720
SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM SRDVYSTDYY RLFNPSGNDF
       730        740        750        760        770        780
CIWCEVGGHT MLPIRWMPPE SIMYRKFTTE SDVWSFGVIL WEIFTYGKQP WFQLSNTEVI
       790        800        810        820        830
ECITQGRVLE RPRVCPKEVY DVMLGCWQRE PQQRLNIKEI YKILHALGKA TPIYLDILG         10         20         30         40         50         60
MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD GNLFPLLEGQ
        70         80         90        100        110        120
DSGNSNGNAS INITDISRNI TSIHIENWRS LHTLNAVDME LYTGLQKLTI KNSGLRSIQP
       130        140        150        160        170        180
RAFAKNPHLR YINLSSNRLT TLSWQLFQTL SLRELQLEQN FFNCSCDIRW MQLWQEQGEA
       190        200        210        220        230        240
KLNSQNLYCI NADGSQLPLF RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD
       250        260        270        280        290        300
VDWIVTGLQS INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
       310        320        330        340        350        360
VYYPPRVVSL EEPELRLEHC IEFVVRGNPP PTLHWLHNGQ PLRESKIIHV EYYQEGEISE
       370        380        390        400        410        420
GCLLFNKPTH YNNGNYTLIA KNPLGTANQT INGHFLKEPF PESTDNFILF DEVSPTPPIT
       430        440        450        460        470        480
VTHKPEEDTF GVSIAVGLAA FACVLLVVLF VMINKYGRRS KFGMKGPVAV ISGEEDSASP
       490        500        510        520        530        540
LHHINHGITT PSSLDAGPDT VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL
       550        560        570        580        590        600
KRELGEGAFG KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
       610        620        630        640        650        660
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE LGLSQMLHIA
       670        680        690        700        710        720
SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM SRDVYSTDYY RLFNPSGNDF
       730        740        750        760        770        780
CIWCEVGGHT MLPIRWMPPE SIMYRKFTTE SDVWSFGVIL WEIFTYGKQP WFQLSNTEVI
       790        800        810        820        830
ECITQGRVLE RPRVCPKEVY DVMLGCWQRE PQQRLNIKEI YKILHALGKA TPIYLDILG

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q16288-1-unknown	MDVSLC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83469
Q16288-1-unknown	MDVSLC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83470
Q16288-1-unknown	MDVSLC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83471
Q16288-1-unknown	MDVSLC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83472
Q16288-32-unknown	CPANCV...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16288-32-unknown	CPANCV...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114971
Q16288-32-unknown	CPANCV...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114972
Q16288-32-unknown	CPANCV...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114973
Q16288-32-unknown	CPANCV...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114974
Q16288-99-unknown	MELYTG...	99	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437773
Q16288-99-unknown	MELYTG...	99	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473656
Q16288-99-unknown	MELYTG...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196941
Q16288-99-unknown	MELYTG...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196942
Q16288-99-unknown	MELYTG...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196943
Q16288-99-unknown	MELYTG...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196944

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SQNLYC	188	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473656
...SQNLYC	188	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155489
...SQNLYC	188	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155490
...SQNLYC	188	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155491
...SQNLYC	188	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155492
...LDILG	839	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LDILG	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79090
...LDILG	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79088
...LDILG	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79089

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)