Q16537: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform - PP2A B subunit isoform B'-epsilon - PP2A B subunit isoform B56-epsilon - PP2A B subunit isoform PR61-epsilon - PP2A B subunit isoform R5-epsilon
Gene names	PPP2R5E
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16537

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform - Isoform 3 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

Sequence View

        10         20         30         40         50         60
MSSAPTTPPS VDKVDGFSRK SVRKARQKRS QSSSQFRSQG KPIELTPLPL LKDVPSSEQP
        70         80         90        100        110        120
ELFLKKLQQC CVIFDFMDTL SDLKMKEYKR STLNELVDYI TISRGCLTEQ TYPEVVRMVS
       130        140        150        160        170        180
CNIFRTLPPS DSNEFDPEED EPTLEASWPH LQLVYEFFIR FLESQEFQPS IAKKYIDQKF
       190        200        210        220        230        240
VLQLLELFDS EDPRERDYLK TVLHRIYGKF LGLRAFIRKQ INNIFLRFVY ETEHFNGVAE
       250        260        270        280        290        300
LLEILGSIIN GFALPLKAEH KQFLVKVLIP LHTVRSLSLF HAQLAYCIVQ FLEKDPSLTE
       310        320        330        340        350        360
PVIRGLMKFW PKTCSQKEVM FLGELEEILD VIEPSQFVKI QEPLFKQIAK CVSSPHFQVA
       370        380        390        400        410        420
ERALYYWNNE YIMSLIEENS NVILPIMFSS LYRISKEHWN PAIVALVYNV LKAFMEMNST
       430        440        450        460
MFDELTATYK SDRQREKKKE KEREELWKKL EDLELKRGLR RDGIIPT         10         20         30         40         50         60
MSSAPTTPPS VDKVDGFSRK SVRKARQKRS QSSSQFRSQG KPIELTPLPL LKDVPSSEQP
        70         80         90        100        110        120
ELFLKKLQQC CVIFDFMDTL SDLKMKEYKR STLNELVDYI TISRGCLTEQ TYPEVVRMVS
       130        140        150        160        170        180
CNIFRTLPPS DSNEFDPEED EPTLEASWPH LQLVYEFFIR FLESQEFQPS IAKKYIDQKF
       190        200        210        220        230        240
VLQLLELFDS EDPRERDYLK TVLHRIYGKF LGLRAFIRKQ INNIFLRFVY ETEHFNGVAE
       250        260        270        280        290        300
LLEILGSIIN GFALPLKAEH KQFLVKVLIP LHTVRSLSLF HAQLAYCIVQ FLEKDPSLTE
       310        320        330        340        350        360
PVIRGLMKFW PKTCSQKEVM FLGELEEILD VIEPSQFVKI QEPLFKQIAK CVSSPHFQVA
       370        380        390        400        410        420
ERALYYWNNE YIMSLIEENS NVILPIMFSS LYRISKEHWN PAIVALVYNV LKAFMEMNST
       430        440        450        460
MFDELTATYK SDRQREKKKE KEREELWKKL EDLELKRGLR RDGIIPT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16537-2-unknown	MSSAPT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16537-1-unknown	MSSAPT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt65733
Q16537-2-Acetylation	SSAPTT...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16537-2-Acetylation	SSAPTT...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q16537-2-Acetylation	SSAPTT...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q16537-2-Acetylation	SSAPTT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110672
Q16537-77-unknown	MDTLSD...	77		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000404632
Q16537-77-unknown	MDTLSD...	77		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q16537-77-unknown	MDTLSD...	77		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131451

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GIIPT	467	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...GIIPT	467	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61351

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)