TopFIND 4.0

Q16651: Prostasin

General Information

Protein names
- Prostasin
- 3.4.21.-
- Channel-activating protease 1
- CAP1
- Serine protease 8
- Prostasin light chain
- Prostasin heavy chain
Gene names PRSS8
Organism Homo sapiens
Protease Family
Protease ID S01.159
Chromosome location
UniProt ID Q16651

3

N-termini

5

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAQKGVLGPG QLGAVAILLY LGLLRSGTGA EGAEAPCGVA PQARITGGSS AVAGQWPWQV 
        70         80         90        100        110        120 
SITYEGVHVC GGSLVSEQWV LSAAHCFPSE HHKEAYEVKL GAHQLDSYSE DAKVSTLKDI 
       130        140        150        160        170        180 
IPHPSYLQEG SQGDIALLQL SRPITFSRYI RPICLPAANA SFPNGLHCTV TGWGHVAPSV 
       190        200        210        220        230        240 
SLLTPKPLQQ LEVPLISRET CNCLYNIDAK PEEPHFVQED MVCAGYVEGG KDACQGDSGG 
       250        260        270        280        290        300 
PLSCPVEGLW YLTGIVSWGD ACGARNRPGV YTLASSYASW IQSKVTELQP RVVPQTQESQ 
       310        320        330        340    
PDSNLCGSHL AFSSAPAQGL LRPILFLPLG LALGLLSPWL SEH

Isoforms

- Isoform 2 of Prostasin

Sequence View

        10         20         30         40         50         60 
MAQKGVLGPG QLGAVAILLY LGLLRSGTGA EGAEAPCGVA PQARITGGSS AVAGQWPWQV 
        70         80         90        100        110        120 
SITYEGVHVC GGSLVSEQWV LSAAHCFPSE HHKEAYEVKL GAHQLDSYSE DAKVSTLKDI 
       130        140        150        160        170        180 
IPHPSYLQEG SQGDIALLQL SRPITFSRYI RPICLPAANA SFPNGLHCTV TGWGHVAPSV 
       190        200        210        220        230        240 
SLLTPKPLQQ LEVPLISRET CNCLYNIDAK PEEPHFVQED MVCAGYVEGG KDACQGDSGG 
       250        260        270        280        290        300 
PLSCPVEGLW YLTGIVSWGD ACGARNRPGV YTLASSYASW IQSKVTELQP RVVPQTQESQ 
       310        320        330        340    
PDSNLCGSHL AFSSAPAQGL LRPILFLPLG LALGLLSPWL SEH



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q16651-30-unknown AEGAEA... 30 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q16651-33-unknown AEAPCG... 33 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q16651-45-unknown ITGGSS... 45 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)