TopFIND 4.0

Q16774: Guanylate kinase

General Information

Protein names
- Guanylate kinase
- 2.7.4.8
- GMP kinase
Gene names GUK1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q16774

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV 
        70         80         90        100        110        120 
MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI 
       130        140        150        160        170        180 
SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE 
       190    
LKEALSEEIK KAQRTGA

Isoforms

- Isoform 2 of Guanylate kinase - Isoform 3 of Guanylate kinase

Sequence View

        10         20         30         40         50         60 
MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV 
        70         80         90        100        110        120 
MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI 
       130        140        150        160        170        180 
SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE 
       190    
LKEALSEEIK KAQRTGA         10         20         30         40         50         60 
MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV 
        70         80         90        100        110        120 
MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI 
       130        140        150        160        170        180 
SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE 
       190    
LKEALSEEIK KAQRTGA



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QRTGA 197 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QRTGA 197 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74524

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)