Q16832: Discoidin domain-containing receptor 2

General Information

Protein names	- Discoidin domain-containing receptor 2 - Discoidin domain receptor 2 - 2.7.10.1 - CD167 antigen-like family member B - Discoidin domain-containing receptor tyrosine kinase 2 - Neurotrophic tyrosine kinase, receptor-related 3 - Receptor protein-tyrosine kinase TKT - Tyrosine-protein kinase TYRO10 - CD167b
Gene names	DDR2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16832

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MILIPRMLLV LFLLLPILSS AKAQVNPAIC RYPLGMSGGQ IPDEDITASS QWSESTAAKY
        70         80         90        100        110        120
GRLDSEEGDG AWCPEIPVEP DDLKEFLQID LHTLHFITLV GTQGRHAGGH GIEFAPMYKI
       130        140        150        160        170        180
NYSRDGTRWI SWRNRHGKQV LDGNSNPYDI FLKDLEPPIV ARFVRFIPVT DHSMNVCMRV
       190        200        210        220        230        240
ELYGCVWLDG LVSYNAPAGQ QFVLPGGSII YLNDSVYDGA VGYSMTEGLG QLTDGVSGLD
       250        260        270        280        290        300
DFTQTHEYHV WPGYDYVGWR NESATNGYIE IMFEFDRIRN FTTMKVHCNN MFAKGVKIFK
       310        320        330        340        350        360
EVQCYFRSEA SEWEPNAISF PLVLDDVNPS ARFVTVPLHH RMASAIKCQY HFADTWMMFS
       370        380        390        400        410        420
EITFQSDAAM YNNSEALPTS PMAPTTYDPM LKVDDSNTRI LIGCLVAIIF ILLAIIVIIL
       430        440        450        460        470        480
WRQFWQKMLE KASRRMLDDE MTVSLSLPSD SSMFNNNRSS SPSEQGSNST YDRIFPLRPD
       490        500        510        520        530        540
YQEPSRLIRK LPEFAPGEEE SGCSGVVKPV QPSGPEGVPH YAEADIVNLQ GVTGGNTYSV
       550        560        570        580        590        600
PAVTMDLLSG KDVAVEEFPR KLLTFKEKLG EGQFGEVHLC EVEGMEKFKD KDFALDVSAN
       610        620        630        640        650        660
QPVLVAVKML RADANKNARN DFLKEIKIMS RLKDPNIIHL LAVCITDDPL CMITEYMENG
       670        680        690        700        710        720
DLNQFLSRHE PPNSSSSDVR TVSYTNLKFM ATQIASGMKY LSSLNFVHRD LATRNCLVGK
       730        740        750        760        770        780
NYTIKIADFG MSRNLYSGDY YRIQGRAVLP IRWMSWESIL LGKFTTASDV WAFGVTLWET
       790        800        810        820        830        840
FTFCQEQPYS QLSDEQVIEN TGEFFRDQGR QTYLPQPAIC PDSVYKLMLS CWRRDTKNRP
       850
SFQEIHLLLL QQGDE

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16832-22-unknown	KAQVNP...	22		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16832-391-unknown	LKVDDS...	391		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417030

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GTRWIS	130	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400309
...NSNPYD	148	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391310
...QQGDE	855	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)