TopFIND 4.0

Q1EHB4: Sodium-coupled monocarboxylate transporter 2

General Information

Protein names
- Sodium-coupled monocarboxylate transporter 2
- Electroneutral sodium monocarboxylate cotransporter
- Low-affinity sodium-lactate cotransporter
- Solute carrier family 5 member 12
Gene names SLC5A12
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q1EHB4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEVKNFAVWD YVVFAALFFI SSGIGVFFAI KERKKATSRE FLVGGRQMSF GPVGLSLTAS 
        70         80         90        100        110        120 
FMSAVTVLGT PSEVYRFGAS FLVFFIAYLF VILLTSELFL PVFYRSGITS TYEYLQLRFN 
       130        140        150        160        170        180 
KPVRYAATVI YIVQTILYTG VVVYAPALAL NQVTGFDLWG SVFATGIVCT FYCTLGGLKA 
       190        200        210        220        230        240 
VVWTDAFQMV VMIVGFLTVL IQGSTHAGGF HNVLEQSTNG SRLHIFDFDV DPLRRHTFWT 
       250        260        270        280        290        300 
ITVGGTFTWL GIYGVNQSTI QRCISCKTEK HAKLALYFNL LGLWIILVCA VFSGLIMYSH 
       310        320        330        340        350        360 
FKDCDPWTSG IISAPDQLMP YFVMEIFATM PGLPGLFVAC AFSGTLSTVA SSINALATVT 
       370        380        390        400        410        420 
FEDFVKSCFP HLSDKLSTWI SKGLCLLFGV MCTSMAVAAS VMGGVVQASL SIHGMCGGPM 
       430        440        450        460        470        480 
LGLFSLGIVF PFVNWKGALG GLLTGITLSF WVAIGAFIYP APASKTWPLP LSTDQCIKSN 
       490        500        510        520        530        540 
VTATGPPVLS SRPGIADTWY SISYLYYSAV GCLGCIVAGV IISLITGRQR GEDIQPLLIR 
       550        560        570        580        590        600 
PVCNLFCFWS KKYKTLCWCG VQHDSGTEQE NLENGSARKQ GAESVLQNGL RRESLVHVPG 
       610    
YDPKDKSYNN MAFETTHF

Isoforms

- Isoform 2 of Sodium-coupled monocarboxylate transporter 2

Sequence View

        10         20         30         40         50         60 
MEVKNFAVWD YVVFAALFFI SSGIGVFFAI KERKKATSRE FLVGGRQMSF GPVGLSLTAS 
        70         80         90        100        110        120 
FMSAVTVLGT PSEVYRFGAS FLVFFIAYLF VILLTSELFL PVFYRSGITS TYEYLQLRFN 
       130        140        150        160        170        180 
KPVRYAATVI YIVQTILYTG VVVYAPALAL NQVTGFDLWG SVFATGIVCT FYCTLGGLKA 
       190        200        210        220        230        240 
VVWTDAFQMV VMIVGFLTVL IQGSTHAGGF HNVLEQSTNG SRLHIFDFDV DPLRRHTFWT 
       250        260        270        280        290        300 
ITVGGTFTWL GIYGVNQSTI QRCISCKTEK HAKLALYFNL LGLWIILVCA VFSGLIMYSH 
       310        320        330        340        350        360 
FKDCDPWTSG IISAPDQLMP YFVMEIFATM PGLPGLFVAC AFSGTLSTVA SSINALATVT 
       370        380        390        400        410        420 
FEDFVKSCFP HLSDKLSTWI SKGLCLLFGV MCTSMAVAAS VMGGVVQASL SIHGMCGGPM 
       430        440        450        460        470        480 
LGLFSLGIVF PFVNWKGALG GLLTGITLSF WVAIGAFIYP APASKTWPLP LSTDQCIKSN 
       490        500        510        520        530        540 
VTATGPPVLS SRPGIADTWY SISYLYYSAV GCLGCIVAGV IISLITGRQR GEDIQPLLIR 
       550        560        570        580        590        600 
PVCNLFCFWS KKYKTLCWCG VQHDSGTEQE NLENGSARKQ GAESVLQNGL RRESLVHVPG 
       610    
YDPKDKSYNN MAFETTHF



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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q1EHB4-1-unknown MEVKNF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q1EHB4-1-unknown MEVKNF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88953

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ETTHF 618 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)