Q1MX18: Protein inscuteable homolog

General Information

Protein names	- Protein inscuteable homolog
Gene names	INSC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q1MX18

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein inscuteable homolog - Isoform 3 of Protein inscuteable homolog - Isoform 4 of Protein inscuteable homolog - Isoform 5 of Protein inscuteable homolog - Isoform 6 of Protein inscuteable homolog

Sequence View

        10         20         30         40         50         60
MRRPPGNGEA ASEGPGGWGL WGVQESRRLC CAGHDRCKQA LLQIGINMMA LPGGRHLDSV
        70         80         90        100        110        120
TLPGQRLHLM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDAQGDLI LAGGPGPGDP
       130        140        150        160        170        180
LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYSA VSRNSLKEMG
       190        200        210        220        230        240
EIEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SMLGQHFGQL LELALTREVQ
       250        260        270        280        290        300
ALVRKIDASD NIYTTESTTG NLFSLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ
       310        320        330        340        350        360
ALRTLASICC VEEGVHQLEK VDGVLCLADI LTDNSHSEAT RAEAAAVVAQ VTSPHLPVTQ
       370        380        390        400        410        420
HLSSFLESME EIVTALVKLC QEASSGEVFL LASAALANIT FFDTMACEML LQLNAIRVLL
       430        440        450        460        470        480
EACSDKQRVD TPYTRDQIVT ILANMSVLEQ CASDIIQENG VQLIMGMLSE KPRSGTPAEV
       490        500        510        520        530        540
AACERVQQKA AVTLARLSRD PDVAREAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL
       550        560        570
RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV         10         20         30         40         50         60
MRRPPGNGEA ASEGPGGWGL WGVQESRRLC CAGHDRCKQA LLQIGINMMA LPGGRHLDSV
        70         80         90        100        110        120
TLPGQRLHLM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDAQGDLI LAGGPGPGDP
       130        140        150        160        170        180
LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYSA VSRNSLKEMG
       190        200        210        220        230        240
EIEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SMLGQHFGQL LELALTREVQ
       250        260        270        280        290        300
ALVRKIDASD NIYTTESTTG NLFSLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ
       310        320        330        340        350        360
ALRTLASICC VEEGVHQLEK VDGVLCLADI LTDNSHSEAT RAEAAAVVAQ VTSPHLPVTQ
       370        380        390        400        410        420
HLSSFLESME EIVTALVKLC QEASSGEVFL LASAALANIT FFDTMACEML LQLNAIRVLL
       430        440        450        460        470        480
EACSDKQRVD TPYTRDQIVT ILANMSVLEQ CASDIIQENG VQLIMGMLSE KPRSGTPAEV
       490        500        510        520        530        540
AACERVQQKA AVTLARLSRD PDVAREAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL
       550        560        570
RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV         10         20         30         40         50         60
MRRPPGNGEA ASEGPGGWGL WGVQESRRLC CAGHDRCKQA LLQIGINMMA LPGGRHLDSV
        70         80         90        100        110        120
TLPGQRLHLM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDAQGDLI LAGGPGPGDP
       130        140        150        160        170        180
LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYSA VSRNSLKEMG
       190        200        210        220        230        240
EIEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SMLGQHFGQL LELALTREVQ
       250        260        270        280        290        300
ALVRKIDASD NIYTTESTTG NLFSLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ
       310        320        330        340        350        360
ALRTLASICC VEEGVHQLEK VDGVLCLADI LTDNSHSEAT RAEAAAVVAQ VTSPHLPVTQ
       370        380        390        400        410        420
HLSSFLESME EIVTALVKLC QEASSGEVFL LASAALANIT FFDTMACEML LQLNAIRVLL
       430        440        450        460        470        480
EACSDKQRVD TPYTRDQIVT ILANMSVLEQ CASDIIQENG VQLIMGMLSE KPRSGTPAEV
       490        500        510        520        530        540
AACERVQQKA AVTLARLSRD PDVAREAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL
       550        560        570
RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV         10         20         30         40         50         60
MRRPPGNGEA ASEGPGGWGL WGVQESRRLC CAGHDRCKQA LLQIGINMMA LPGGRHLDSV
        70         80         90        100        110        120
TLPGQRLHLM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDAQGDLI LAGGPGPGDP
       130        140        150        160        170        180
LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYSA VSRNSLKEMG
       190        200        210        220        230        240
EIEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SMLGQHFGQL LELALTREVQ
       250        260        270        280        290        300
ALVRKIDASD NIYTTESTTG NLFSLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ
       310        320        330        340        350        360
ALRTLASICC VEEGVHQLEK VDGVLCLADI LTDNSHSEAT RAEAAAVVAQ VTSPHLPVTQ
       370        380        390        400        410        420
HLSSFLESME EIVTALVKLC QEASSGEVFL LASAALANIT FFDTMACEML LQLNAIRVLL
       430        440        450        460        470        480
EACSDKQRVD TPYTRDQIVT ILANMSVLEQ CASDIIQENG VQLIMGMLSE KPRSGTPAEV
       490        500        510        520        530        540
AACERVQQKA AVTLARLSRD PDVAREAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL
       550        560        570
RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV         10         20         30         40         50         60
MRRPPGNGEA ASEGPGGWGL WGVQESRRLC CAGHDRCKQA LLQIGINMMA LPGGRHLDSV
        70         80         90        100        110        120
TLPGQRLHLM QVDSVQRWME DLKLMTECEC MCVLQAKPIS LEEDAQGDLI LAGGPGPGDP
       130        140        150        160        170        180
LQLLLKRGWV ISTELRRIGQ KLAQDRWARV HSMSVRLTCH ARSMVSEYSA VSRNSLKEMG
       190        200        210        220        230        240
EIEKLLMEKC SELSAVTERC LQVENEHVLK SMKACVSETL SMLGQHFGQL LELALTREVQ
       250        260        270        280        290        300
ALVRKIDASD NIYTTESTTG NLFSLTQEGA PLCRIIAKEG GVVALFKVCR QDSFRCLYPQ
       310        320        330        340        350        360
ALRTLASICC VEEGVHQLEK VDGVLCLADI LTDNSHSEAT RAEAAAVVAQ VTSPHLPVTQ
       370        380        390        400        410        420
HLSSFLESME EIVTALVKLC QEASSGEVFL LASAALANIT FFDTMACEML LQLNAIRVLL
       430        440        450        460        470        480
EACSDKQRVD TPYTRDQIVT ILANMSVLEQ CASDIIQENG VQLIMGMLSE KPRSGTPAEV
       490        500        510        520        530        540
AACERVQQKA AVTLARLSRD PDVAREAVRL SCMSRLIELC RSPSERNSSD AVLVACLAAL
       550        560        570
RRLAGVCPEG LQDSDFQQLV QPRLVDSFLL CSNMEESFV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q1MX18-1-unknown	MRRPPG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q1MX18-48-unknown	MMALPG...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77928
Q1MX18-48-unknown	MMALPG...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77930
Q1MX18-48-unknown	MMALPG...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77931
Q1MX18-48-unknown	MMALPG...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77932
Q1MX18-48-unknown	MMALPG...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000368874
Q1MX18-48-unknown	MMALPG...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435022
Q1MX18-48-unknown	MMALPG...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436194
Q1MX18-48-unknown	MMALPG...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436113
Q1MX18-48-unknown	MMALPG...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389161

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EESFV	579	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EESFV	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73547
...EESFV	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73548
...EESFV	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73546
...EESFV	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73549

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)