TopFIND 4.0

Q2A121: Alpha-ketoglutarate-dependent dioxygenase FTO {ECO:0000305}

General Information

Protein names
- Alpha-ketoglutarate-dependent dioxygenase FTO {ECO:0000305}
- Fat mass and obesity-associated protein {ECO:0000303|PubMed:18218688}
- U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO {ECO:0000305}
- 1.14.11.- {ECO:0000250|UniProtKB:Q9C0B1}
- U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO {ECO:0000305}
- 1.14.11.- {ECO:0000250|UniProtKB:Q9C0B1}
- mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO {ECO:0000305}
- m6A(m)-demethylase FTO {ECO:0000305}
- 1.14.11.- {ECO:0000250|UniProtKB:Q9C0B1}
- mRNA N(6)-methyladenosine demethylase FTO {ECO:0000305}
- 1.14.11.53 {ECO:0000250|UniProtKB:Q9C0B1}
- tRNA N1-methyl adenine demethylase FTO {ECO:0000305}
- 1.14.11.- {ECO:0000250|UniProtKB:Q9C0B1}
Gene names Fto
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q2A121

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV FREAGSIPEE 
        70         80         90        100        110        120 
LHKEVPEAFL TLHKHGCLFR DLVRIQGKDV LTPVSRILIG DPGCTYKYLN TRLFTVPWPV 
       130        140        150        160        170        180 
KGCTINYTEA EIAAACQTFL KLNDYLQVET IQALEELAIK EKANEDAVPL CMAEFPRAGV 
       190        200        210        220        230        240 
GPSCDDEVDL KSRAAYNVTL LNFMDPQKMP YLKEEPYFGM GKMAVSWHHD ENLVDRSAVA 
       250        260        270        280        290        300 
VYSYSCEGSE DESDDESSFE GRDPDTWHVG FKISWDIETP GLTIPLHQGD CYFMLDDLNA 
       310        320        330        340        350        360 
THQHCVLAGS QPRFSSTHRV AECSTGTLDY ILQRCQLALQ NVLNDSDNGD VSLKSFEPAV 
       370        380        390        400        410        420 
LKQGEEIHNE VEFEWLRQFW FQGNRYKICT DWWCEPMTQL EGLWKKMESV TNAVLREVKR 
       430        440        450        460        470        480 
EGLSVEQRSE ILSAVLIPLT MRQNLRKEWH ARCQARVVRT LPAQQKPDCR PYWEKDDPSM 
       490        500    
PLPFDLTDVV SEIRSQLLEA RS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q2A121-1-unknown MKRVQT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LEARS 502 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)