TopFIND 4.0

Q2I0M5: R-spondin-4

General Information

Protein names
- R-spondin-4
- Roof plate-specific spondin-4
- hRspo4
Gene names RSPO4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q2I0M5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRAPLCLLLL VAHAVDMLAL NRRKKQVGTG LGGNCTGCII CSEENGCSTC QQRLFLFIRR 
        70         80         90        100        110        120 
EGIRQYGKCL HDCPPGYFGI RGQEVNRCKK CGATCESCFS QDFCIRCKRQ FYLYKGKCLP 
       130        140        150        160        170        180 
TCPPGTLAHQ NTRECQGECE LGPWGGWSPC THNGKTCGSA WGLESRVREA GRAGHEEAAT 
       190        200        210        220        230    
CQVLSESRKC PIQRPCPGER SPGQKKGRKD RRPRKDRKLD RRLDVRPRQP GLQP

Isoforms

- Isoform 2 of R-spondin-4

Sequence View

        10         20         30         40         50         60 
MRAPLCLLLL VAHAVDMLAL NRRKKQVGTG LGGNCTGCII CSEENGCSTC QQRLFLFIRR 
        70         80         90        100        110        120 
EGIRQYGKCL HDCPPGYFGI RGQEVNRCKK CGATCESCFS QDFCIRCKRQ FYLYKGKCLP 
       130        140        150        160        170        180 
TCPPGTLAHQ NTRECQGECE LGPWGGWSPC THNGKTCGSA WGLESRVREA GRAGHEEAAT 
       190        200        210        220        230    
CQVLSESRKC PIQRPCPGER SPGQKKGRKD RRPRKDRKLD RRLDVRPRQP GLQP



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q2I0M5-1-unknown MRAPLC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88285
    Q2I0M5-20-unknown LNRRKK... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q2I0M5-20-unknown LNRRKK... 20 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112493

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PGLQP 234 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PGLQP 234 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83903

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)