TopFIND 4.0

Q2MKA7: R-spondin-1

General Information

Protein names
- R-spondin-1
- Roof plate-specific spondin-1
- hRspo1
Gene names RSPO1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q2MKA7

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLGLCVVAL VLSWTHLTIS SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL 
        70         80         90        100        110        120 
FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL 
       130        140        150        160        170        180 
HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL 
       190        200        210        220        230        240 
HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR 
       250        260    
RRKGQQQQQQ QGTVGPLTSA GPA

Isoforms

- Isoform 2 of R-spondin-1 - Isoform 3 of R-spondin-1

Sequence View

        10         20         30         40         50         60 
MRLGLCVVAL VLSWTHLTIS SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL 
        70         80         90        100        110        120 
FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL 
       130        140        150        160        170        180 
HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL 
       190        200        210        220        230        240 
HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR 
       250        260    
RRKGQQQQQQ QGTVGPLTSA GPA         10         20         30         40         50         60 
MRLGLCVVAL VLSWTHLTIS SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL 
        70         80         90        100        110        120 
FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL 
       130        140        150        160        170        180 
HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL 
       190        200        210        220        230        240 
HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR 
       250        260    
RRKGQQQQQQ QGTVGPLTSA GPA



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q2MKA7-1-unknown MRLGLC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88281
    Q2MKA7-21-unknown SRGIKG... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q2MKA7-21-unknown SRGIKG... 21 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112754

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)