Q2NL51: Glycogen synthase kinase-3 alpha
Protein names | - Glycogen synthase kinase-3 alpha - GSK-3 alpha - 2.7.11.26 - Serine/threonine-protein kinase GSK3A - 2.7.11.1 {ECO:0000269|PubMed:22539723} |
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Gene names | Gsk3a |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q2NL51 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSGGGPSGGG PGGSGRARTS SFAEPGGGGG GGGGGPGGSA SGPGGTGGGK ASVGAMGGGV
70 80 90 100 110 120
GASSSGGGPS GSGGGGSGGP GAGTSFPPPG VKLGRDSGKV TTVVATVGQG PERSQEVAYT
130 140 150 160 170 180
DIKVIGNGSF GVVYQARLAE TRELVAIKKV LQDKRFKNRE LQIMRKLDHC NIVRLRYFFY
190 200 210 220 230 240
SSGEKKDELY LNLVLEYVPE TVYRVARHFT KAKLITPIIY IKVYMYQLFR SLAYIHSQGV
250 260 270 280 290 300
CHRDIKPQNL LVDPDTAVLK LCDFGSAKQL VRGEPNVSYI CSRYYRAPEL IFGATDYTSS
310 320 330 340 350 360
IDVWSAGCVL AELLLGQPIF PGDSGVDQLV EIIKVLGTPT REQIREMNPN YTEFKFPQIK
370 380 390 400 410 420
AHPWTKVFKS SKTPPEAIAL CSSLLEYTPS SRLSPLEACA HSFFDELRRL GAQLPNDRPL
430 440 450 460 470 480
PPLFNFSPGE LSIQPSLNAI LIPPHLRSPA GPASPLTTSY NPSSQALTEA QTGQDWQPSD
490
ATTATLASSS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q2NL51-2-unknown | MSGGGP... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q2NL51-2-unknown | MSGGGP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q2NL51-2-Acetylation | SGGGPS... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q2NL51-2-Acetylation | SGGGPS... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
Q2NL51-145-unknown | VAIKKV... | 145 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30415 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ETRELV | 144 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30415 | |||
...LASSS | 490 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 144 | RELV.|.VAIK | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> GSK3A_MOUSE @144 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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