TopFIND 4.0

Q2TBA0: Kelch-like protein 40 {ECO:0000305}

General Information

Protein names
- Kelch-like protein 40 {ECO:0000305}
- Kelch repeat and BTB domain-containing protein 5
- Sarcosynapsin {ECO:0000303|Ref.1}
Gene names KLHL40
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q2TBA0

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 
        70         80         90        100        110        120 
RFLAEPERAG ELHLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 
       130        140        150        160        170        180 
VSFLQKRLCL SNCLAVFRLG LLLDCARLAV AARDFICAHF TLVARDADFL GLSADELIAI 
       190        200        210        220        230        240 
ISSDGLNVEK EEAVFEAVMR WAGSGDAEAQ AERQRALPTV FESVRCRLLP RAFLESRVER 
       250        260        270        280        290        300 
HPLVRAQPEL LRKVQMVKDA HEGRITTLRK KKKGKDGAGA KEADKGTSKA KAEEDEEAER 
       310        320        330        340        350        360 
ILPGILNDTL RFGMFLQDLI FMISEEGAVA YDPAANECYC ASLSNQVPKN HVSLVTKENQ 
       370        380        390        400        410        420 
VFVAGGLFYN EDNKEDPMSA YFLQFDHLDS EWLGMPPLPS PRCLFGLGEA LNSIYVVGGR 
       430        440        450        460        470        480 
EIKDGERCLD SVMCYDRLSF KWGESDPLPY VVYGHTVLSH MDLVYVIGGK GSDRKCLNKM 
       490        500        510        520        530        540 
CVYDPKKFEW KELAPMQTAR SLFGATVHDG RIIVAAGVTD TGLTSSAEVY SITDNKWAPF 
       550        560        570        580        590        600 
EAFPQERSSL SLVSLVGTLY AIGGFATLET ESGELVPTEL NDIWRYNEEE KKWEGVLREI 
       610        620    
AYAAGATFLP VRLNVLCLTK M

Isoforms

- Isoform 2 of Kelch-like protein 40

Sequence View

        10         20         30         40         50         60 
MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 
        70         80         90        100        110        120 
RFLAEPERAG ELHLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 
       130        140        150        160        170        180 
VSFLQKRLCL SNCLAVFRLG LLLDCARLAV AARDFICAHF TLVARDADFL GLSADELIAI 
       190        200        210        220        230        240 
ISSDGLNVEK EEAVFEAVMR WAGSGDAEAQ AERQRALPTV FESVRCRLLP RAFLESRVER 
       250        260        270        280        290        300 
HPLVRAQPEL LRKVQMVKDA HEGRITTLRK KKKGKDGAGA KEADKGTSKA KAEEDEEAER 
       310        320        330        340        350        360 
ILPGILNDTL RFGMFLQDLI FMISEEGAVA YDPAANECYC ASLSNQVPKN HVSLVTKENQ 
       370        380        390        400        410        420 
VFVAGGLFYN EDNKEDPMSA YFLQFDHLDS EWLGMPPLPS PRCLFGLGEA LNSIYVVGGR 
       430        440        450        460        470        480 
EIKDGERCLD SVMCYDRLSF KWGESDPLPY VVYGHTVLSH MDLVYVIGGK GSDRKCLNKM 
       490        500        510        520        530        540 
CVYDPKKFEW KELAPMQTAR SLFGATVHDG RIIVAAGVTD TGLTSSAEVY SITDNKWAPF 
       550        560        570        580        590        600 
EAFPQERSSL SLVSLVGTLY AIGGFATLET ESGELVPTEL NDIWRYNEEE KKWEGVLREI 
       610        620    
AYAAGATFLP VRLNVLCLTK M



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q2TBA0-1-unknown MALGLE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q2TBA0-1-unknown MALGLE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79115

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CLTKM 621 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)