Q2TL32: E3 ubiquitin-protein ligase UBR4
Protein names | - E3 ubiquitin-protein ligase UBR4 - 2.3.2.27 - N-recognin-4 - RING-type E3 ubiquitin transferase UBR4 - Zinc finger UBR1-type protein 1 |
---|---|
Gene names | Ubr4 |
Organism | Rattus norvegicus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q2TL32 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MATSGGEEAA AAAPAPGAPA TGQDTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVPSPP ISPQALVEGE NDEQSSTEQA SAVKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVVAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEEDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHFQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILHLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAVLS IMAQSTSTQR VQRLIDSVPL TNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA SGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE QHMATLASII KEVDKDGLKG SSDEDFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPL SSGPWPLYIH PQGLSVLSRL LLIWQHKAGA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLTTM KQSALQGVVP SETEDLNIEH LQLLLLIFHS FSEKGRRAIL TTLVQSIQEL
850 860 870 880 890 900
SVNMEVQMRS APLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSSS
910 920 930 940 950 960
SSRRANIPLY HGFKEVEENW SKHFSSDAAP QPRFYCVLST EASEEDLNRL DSEACEVLFS
970 980 990 1000 1010 1020
KLVKYDELYS SLTALLAAGS QLDTVKRKEN KNMTALEACA LQYYFLILWR ILGILPPSKT
1030 1040 1050 1060 1070 1080
YMNQLAMNSP EMSECDILHT LRWSSRLRIS SYVSWIKDHL IRQGMRPEHA GSLVELAASK
1090 1100 1110 1120 1130 1140
CSSVKYDVEI VEEYFARQIS SFCSIDCTTV LQLHEIPSLQ SIYTLDAAVS KVQVSLDEHF
1150 1160 1170 1180 1190 1200
SKMAAETDPH KSSEITKNLL PATLQLIDTY ASFTRAYLLQ NLNEEGSTEK PSQEKLHGFA
1210 1220 1230 1240 1250 1260
AVLAIGSSRC KANTLGPTLV QNLPSSVQSV CESWNNINTN EFPNIGSWRN AFANDTIPSE
1270 1280 1290 1300 1310 1320
SYISAVQAAH LGTLCGQSLP LAASLKHALL SLVRLTGDLI VWSDEMNPAQ VIRALLPLLL
1330 1340 1350 1360 1370 1380
ESSTESAAEI SSNSLERILG PAESDEFLAR VYEKLITGCY NILANHADPS SGLDESVLEE
1390 1400 1410 1420 1430 1440
CLQYLEKQLE SSQARKAMEE FFSDGGELVQ IMMATANEDL SAKFCNRVLK FFTKLFQLTE
1450 1460 1470 1480 1490 1500
KSPNPSLLHL CGSLAQLACV EPVRLQAWLT RMTTSPPKDS DQLEVIQENR QLLQLLTTYI
1510 1520 1530 1540 1550 1560
VRENSQVGEG VCAVLLGTLT PMATDMLANG DGTGFPELMV VMATLASAGQ GAGHLQLHNA
1570 1580 1590 1600 1610 1620
AVDWLGRCKK YLSQKNVVEK LNANVMHGKH VMVLECTCHI MSYLADVTNA LSQSNGQGPS
1630 1640 1650 1660 1670 1680
HLSVDGEERA IEVDSDWVEE LAVEEEDSQA EDSDEDSLCN KLCTFTITQK EFMNQHWYHC
1690 1700 1710 1720 1730 1740
HTCKMVDGVG VCTVCAKVCH KDHEISYAKY GSFFCDCGAK EDGSCLALVK RTPSSGMSST
1750 1760 1770 1780 1790 1800
MKESAFQSEP RVSESLVRHA STSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVDK VVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLSV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYM YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYSQGK SFAATVSRST LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITAR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTMEI
2350 2360 2370 2380 2390 2400
SNNSSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADRK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEDF PSASVSSVCP PNLNQSNSTG
2470 2480 2490 2500 2510 2520
DSDSAAPATT SGTVLERLVV SSLEALESCF AVGPIIEKER NKHAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHSSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AVTRPNNLVH FTESKLPQME TEGAEEGKEP QKQVEGDGCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPDGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASGVCACN SSVTLSAPAS
2890 2900 2910 2920 2930 2940
DDEGSTAATD GSTLRTSPAD HGGSVGSESG GSAVDSVAGE HSVSGRSSAY GDATAEGHPA
2950 2960 2970 2980 2990 3000
GPGSVSSSTG AISTTTGHQE GDGSEGEGEG EAEGDVHTSN RLHMVRLMLL ERLLQTLPQL
3010 3020 3030 3040 3050 3060
RNVGGVRAIP YMQVILMLTT DLDGEDEKDK GALDNLLAQL IAELGMDKKD VSKKNERSAL
3070 3080 3090 3100 3110 3120
NEVHLVVMRL LSVFMSRTKS GSKSSICESS SLISSATAAA LLSSGAVDYC LHVLKSLLEY
3130 3140 3150 3160 3170 3180
WKGQQSEEEP VTTSQLLKPH TTSSPPDMSP FFLRQYVKGH AADVFEAYTQ LLTEMVLRLP
3190 3200 3210 3220 3230 3240
YQIKKIADTS SRIPPPVFDH SWFYFLSEYL MIQQTPFVRR QVRKLLLFIC GSKEKYRQLR
3250 3260 3270 3280 3290 3300
DLHTLDSHVR GIKKLLEEQG IFLRASVVTA SSGSALQYDT LISLMEHLKA CAEIAAQRTI
3310 3320 3330 3340 3350 3360
NWQKFCIKDD SVLYFLLQVS FLVDEGVSPV LLQLLSCALC GSKVLAALAA STGSSSVASS
3370 3380 3390 3400 3410 3420
APPAASSGQT TTQSKSSTKK SKKEKKEKEK EGESSGSQED QLCTALVNQL NRFADKETLI
3430 3440 3450 3460 3470 3480
QFLRCFLLES NSSSVRWQAH CLTLHIYRNS NKAQQELLLD LMWSIWPELP AYGRKAAQFV
3490 3500 3510 3520 3530 3540
DLLGYFSLKT AQTEKKLKEY SQKAVEILRT QNHILTNHPN SNIYNTLSGL VEFDGYYLES
3550 3560 3570 3580 3590 3600
DPCLVCNNPE VPFCYIKLSS IKVDTRYTTT QQVVKLIGSH TISKVTVKIG DLKRTKMVRT
3610 3620 3630 3640 3650 3660
INLYYNNRTV QAIVELKNKP ARWHKAKKVQ LTPGQTEVKI DLPLPIVASN LMIEFADFYE
3670 3680 3690 3700 3710 3720
NYQASTETLQ CPRCSASVPA NPGVCGNCGE NVYQCHKCRS INYDEKDPFL CNACGFCKYA
3730 3740 3750 3760 3770 3780
RFDFMLYAKP CCAVDPIENE EDRKKAVSNI NTLLDKADRV YHQLMGHRPQ LENLLCKVNE
3790 3800 3810 3820 3830 3840
AAPEKPQEDS GTAGGISSTS ASVNRYILQL AQEYCGDCKN SFDELSKIIQ KVFASRKELL
3850 3860 3870 3880 3890 3900
EYDLQQREAA TKSSRTSVQP TFTASQYRAL SVLGCGHTSS TKCYGCASAV TEHCITLLRA
3910 3920 3930 3940 3950 3960
LATNPALRHI LVSQGLIREL FDYNLRRGAA AIREEVRQLM CLLTRDNPEA TQQMNDLIIG
3970 3980 3990 4000 4010 4020
KVSTALKGHW ANPDLASSLQ YEMLLLTDSI SKEDSCWELR LRCALSLFLM AVNIKTPVVV
4030 4040 4050 4060 4070 4080
ENITLMCLRI LQKLIKPPAP TSKKNKDVPV EALTTVKPYC NEIHAQAQLW LKRDPKASYE
4090 4100 4110 4120 4130 4140
AWKKCLPIRG VDGNGKSPSK SELHRLYLTE KYVWRWKQFL SRRGKRTTPL DLKLGHNNWL
4150 4160 4170 4180 4190 4200
RQVLFTPATQ AARQAACTIV EALASVPSRK QQVLDLLTSY LDELSVAGEC AAEYLALYQK
4210 4220 4230 4240 4250 4260
LIASCHWKVY LAARGVLPYV GNLITKEIAR LLALEEATLS TDLQQGYALK SLTGLLSSFV
4270 4280 4290 4300 4310 4320
EVESIKRHFK SRLVGTVLNG YLCLRKLVLQ RTKLIDETQD MLLEMLEDMT TGTESETKAF
4330 4340 4350 4360 4370 4380
MAVCIETAKR YNLDDYRTPV FIFERLCSII YPEENEVTEF FVTLEKDPQQ EDFLQGRMPG
4390 4400 4410 4420 4430 4440
NPYSSNEPGI GPLMRDIKNK ICQDCDLVAL LEDDSGMELL VNNKIISLDL PVAEVYKKVW
4450 4460 4470 4480 4490 4500
CTTNEGEPMR IVYRMRGLLG DATEEFIESL DSTTDEEEDE EEVYRMAGVM AQCGGLQCML
4510 4520 4530 4540 4550 4560
NRLAGVKDFK QGRHLLTVLL KLFSYCVKVK VNRQQLVKLE MNTLNVMLGT LNLALVAEQE
4570 4580 4590 4600 4610 4620
SKDSGGAAVA EQVLSIMEII LDESNAEPLS EDKGNLLLTG DKDQLVMLLD QINSTFVRSN
4630 4640 4650 4660 4670 4680
PSVLQGLLRI IPYLSFGEVE KMQILVERFK PYCSFDKYDE DHSGDDKVFL DCFCKIAAGI
4690 4700 4710 4720 4730 4740
KNNSNGHQLK DLILQKGITQ SALDYMKKHI PSAKNLDADI WKKFLSRPAL PFILRLLRGL
4750 4760 4770 4780 4790 4800
AMQHPATQVL IGTDSITSLH KLEQVSSDEG IGTLAENLLE ALREHPDVNK KIDAARRETR
4810 4820 4830 4840 4850 4860
AEKKRMAMAM RQKALGTLGM TTNEKGQVVT KTALLKQMEE LIEEPGLTCC ICREGYKFQP
4870 4880 4890 4900 4910 4920
TKVLGIYTFT KRVALEEMEN KPRKQQGYST VSHFNIVHYD CHLAAVRLAR GREEWESAAL
4930 4940 4950 4960 4970 4980
QNANTKCNGL LPVWGPHVPE SAFATCLARH NTYLQECTGQ REPTYQLNIH DIKLLFLRFA
4990 5000 5010 5020 5030 5040
MEQSFSADTG GGGRESNIHL IPYIIHTVLY VLNTTRATSR EEKNLQGFLE QPREKWTESA
5050 5060 5070 5080 5090 5100
FDVDGPHYFT ILALHVLPPE QWKATRVEIL RRLLVASHAR AVAPGGATRL TDKAVKDYSA
5110 5120 5130 5140 5150 5160
YRSSLLFWAL VDLIYNMFKK VPTSNTEGGW SCSLAEYIRH NDMPIYEAAD KALKTFQEEF
5170 5180 5190
MPVETFSEFL DAAGLLSEIT DPESFLKDLL NSVP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q2TL32-1-unknown | MATSGG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LNSVP | 5194 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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