TopFIND 4.0

Q2WF71: Leucine-rich repeat and fibronectin type III domain-containing protein 1

General Information

Protein names
- Leucine-rich repeat and fibronectin type III domain-containing protein 1
- Synaptic adhesion-like molecule 2
- Synaptic differentiation-enhancing molecule 1
Gene names Lrfn1
Organism Mus musculus
Protease Family
Protease ID I43.001
Chromosome location
UniProt ID Q2WF71

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPGPFSSGL FSPPPAALPF LLLLWAGASR GQPCPGRCIC QNVAPTLTML CAKTGLLFVP 
        70         80         90        100        110        120 
PAIDRRVVEL RLTDNFIAAV RRRDFANMTS LVHLTLSRNT IGQVAAGAFA DLRALRALHL 
       130        140        150        160        170        180 
DSNRLAEVRG DQLRGLGNLR HLILGNNQIR KVESAAFDAF LSTVEDLDLS YNNLEALPWE 
       190        200        210        220        230        240 
AVGQMVNLNT LTLDHNLIDH IAEGTFVQLH KLVRLDMTSN RLHKLPPDGL FLRSQGGGPK 
       250        260        270        280        290        300 
PPTPLTVSFG GNPLHCNCEL LWLRRLTRED DLETCATPEH LTDRYFWSIP EEEFLCEPPL 
       310        320        330        340        350        360 
ITRQAGGRAL VVEGQAVSLR CRAVGDPEPV VHWVAPDGRL LGNSSRTRVR GDGTLDVTIT 
       370        380        390        400        410        420 
TLRDSGTFTC IASNAAGEAT APVEVCVVPL PLMAPPPAAP PPLTEPGSSD IATPGRPGAN 
       430        440        450        460        470        480 
DSTSERRLVA AELTSSSVLI RWPAQRPVPG IRMYQVQYNS SADDSLVYRM IPSTSQTFLV 
       490        500        510        520        530        540 
NDLAAGRAYD LCVLAVYDDG ATALPATRVV GCVQFTTAGD PAPCRPLRAH FLGGTMIIAI 
       550        560        570        580        590        600 
GGVIVASVLV FIVLLMIRYK VYGDGDSRRI KGTSRTPPRV SHVCSQTNGA GAQQASAPPA 
       610        620        630        640        650        660 
PDRYEALREV AVPAAIEAKA MEAEATSTEL EVVLGRSLGG SATSLCLLPS EETSGEESRA 
       670        680        690        700        710        720 
MTGPRRSRSG ALGPPTSAPP TLALVPGGAP ARPRPQQRYS FDGDYGALFQ SHSYPRRARR 
       730        740        750        760    
TKRHRSTPHL DGAGGGAAGE DGDLGLGSAR ARLAFTSTEW MLESTV

Isoforms

- Isoform 2 of Leucine-rich repeat and fibronectin type III domain-containing protein 1 - Isoform 3 of Leucine-rich repeat and fibronectin type III domain-containing protein 1

Sequence View

        10         20         30         40         50         60 
MAPGPFSSGL FSPPPAALPF LLLLWAGASR GQPCPGRCIC QNVAPTLTML CAKTGLLFVP 
        70         80         90        100        110        120 
PAIDRRVVEL RLTDNFIAAV RRRDFANMTS LVHLTLSRNT IGQVAAGAFA DLRALRALHL 
       130        140        150        160        170        180 
DSNRLAEVRG DQLRGLGNLR HLILGNNQIR KVESAAFDAF LSTVEDLDLS YNNLEALPWE 
       190        200        210        220        230        240 
AVGQMVNLNT LTLDHNLIDH IAEGTFVQLH KLVRLDMTSN RLHKLPPDGL FLRSQGGGPK 
       250        260        270        280        290        300 
PPTPLTVSFG GNPLHCNCEL LWLRRLTRED DLETCATPEH LTDRYFWSIP EEEFLCEPPL 
       310        320        330        340        350        360 
ITRQAGGRAL VVEGQAVSLR CRAVGDPEPV VHWVAPDGRL LGNSSRTRVR GDGTLDVTIT 
       370        380        390        400        410        420 
TLRDSGTFTC IASNAAGEAT APVEVCVVPL PLMAPPPAAP PPLTEPGSSD IATPGRPGAN 
       430        440        450        460        470        480 
DSTSERRLVA AELTSSSVLI RWPAQRPVPG IRMYQVQYNS SADDSLVYRM IPSTSQTFLV 
       490        500        510        520        530        540 
NDLAAGRAYD LCVLAVYDDG ATALPATRVV GCVQFTTAGD PAPCRPLRAH FLGGTMIIAI 
       550        560        570        580        590        600 
GGVIVASVLV FIVLLMIRYK VYGDGDSRRI KGTSRTPPRV SHVCSQTNGA GAQQASAPPA 
       610        620        630        640        650        660 
PDRYEALREV AVPAAIEAKA MEAEATSTEL EVVLGRSLGG SATSLCLLPS EETSGEESRA 
       670        680        690        700        710        720 
MTGPRRSRSG ALGPPTSAPP TLALVPGGAP ARPRPQQRYS FDGDYGALFQ SHSYPRRARR 
       730        740        750        760    
TKRHRSTPHL DGAGGGAAGE DGDLGLGSAR ARLAFTSTEW MLESTV         10         20         30         40         50         60 
MAPGPFSSGL FSPPPAALPF LLLLWAGASR GQPCPGRCIC QNVAPTLTML CAKTGLLFVP 
        70         80         90        100        110        120 
PAIDRRVVEL RLTDNFIAAV RRRDFANMTS LVHLTLSRNT IGQVAAGAFA DLRALRALHL 
       130        140        150        160        170        180 
DSNRLAEVRG DQLRGLGNLR HLILGNNQIR KVESAAFDAF LSTVEDLDLS YNNLEALPWE 
       190        200        210        220        230        240 
AVGQMVNLNT LTLDHNLIDH IAEGTFVQLH KLVRLDMTSN RLHKLPPDGL FLRSQGGGPK 
       250        260        270        280        290        300 
PPTPLTVSFG GNPLHCNCEL LWLRRLTRED DLETCATPEH LTDRYFWSIP EEEFLCEPPL 
       310        320        330        340        350        360 
ITRQAGGRAL VVEGQAVSLR CRAVGDPEPV VHWVAPDGRL LGNSSRTRVR GDGTLDVTIT 
       370        380        390        400        410        420 
TLRDSGTFTC IASNAAGEAT APVEVCVVPL PLMAPPPAAP PPLTEPGSSD IATPGRPGAN 
       430        440        450        460        470        480 
DSTSERRLVA AELTSSSVLI RWPAQRPVPG IRMYQVQYNS SADDSLVYRM IPSTSQTFLV 
       490        500        510        520        530        540 
NDLAAGRAYD LCVLAVYDDG ATALPATRVV GCVQFTTAGD PAPCRPLRAH FLGGTMIIAI 
       550        560        570        580        590        600 
GGVIVASVLV FIVLLMIRYK VYGDGDSRRI KGTSRTPPRV SHVCSQTNGA GAQQASAPPA 
       610        620        630        640        650        660 
PDRYEALREV AVPAAIEAKA MEAEATSTEL EVVLGRSLGG SATSLCLLPS EETSGEESRA 
       670        680        690        700        710        720 
MTGPRRSRSG ALGPPTSAPP TLALVPGGAP ARPRPQQRYS FDGDYGALFQ SHSYPRRARR 
       730        740        750        760    
TKRHRSTPHL DGAGGGAAGE DGDLGLGSAR ARLAFTSTEW MLESTV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SLVYRM 469 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75551
    ...LESTV 766 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)