TopFIND 4.0

Q32M21: Gasdermin-A2

General Information

Protein names
- Gasdermin-A2
- Gasdermin-2
Gene names Gsdma2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q32M21

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSMFEDVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG ARYVRTDYTL 
        70         80         90        100        110        120 
LDVLEPGSSP SDPTLLGNFS FKNMLDVRVE GDVEVPTMMK VKGTVGLSQS STLEVQMLSV 
       130        140        150        160        170        180 
APTALENLHM ERKLSADHPF LKEMREYKQN LYVVMEVVKA KQEVTLKRAS NAISKFSLNL 
       190        200        210        220        230        240 
PSLGLQGSVN HKEAVTIPKG CVLAYRVRQL IIYGKDEWGI PYICTDNMPT FNPLCVLQRQ 
       250        260        270        280        290        300 
GSTVQMISGE MHEDFKTLKK EVQQETQEVE KLSPVGRSSL LTSLSHLLGK KKELQDLEQM 
       310        320        330        340        350        360 
LEGALDKGHE VTLEALPKDV LLLKDAMDAI LYFLGALTEL SEEQLKILVK SLENKVLPVQ 
       370        380        390        400        410        420 
LKLVESILEQ NFLQDKEDVF PLRPDLLSSL GEEDQILTEA LVGLSGLEVQ RSGPQYTWNP 
       430        440    
DTCHNLCALY AGLSLLHLLS RDS

Isoforms

- Isoform 2 of Gasdermin-A2 - Isoform 3 of Gasdermin-A2

Sequence View

        10         20         30         40         50         60 
MSMFEDVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG ARYVRTDYTL 
        70         80         90        100        110        120 
LDVLEPGSSP SDPTLLGNFS FKNMLDVRVE GDVEVPTMMK VKGTVGLSQS STLEVQMLSV 
       130        140        150        160        170        180 
APTALENLHM ERKLSADHPF LKEMREYKQN LYVVMEVVKA KQEVTLKRAS NAISKFSLNL 
       190        200        210        220        230        240 
PSLGLQGSVN HKEAVTIPKG CVLAYRVRQL IIYGKDEWGI PYICTDNMPT FNPLCVLQRQ 
       250        260        270        280        290        300 
GSTVQMISGE MHEDFKTLKK EVQQETQEVE KLSPVGRSSL LTSLSHLLGK KKELQDLEQM 
       310        320        330        340        350        360 
LEGALDKGHE VTLEALPKDV LLLKDAMDAI LYFLGALTEL SEEQLKILVK SLENKVLPVQ 
       370        380        390        400        410        420 
LKLVESILEQ NFLQDKEDVF PLRPDLLSSL GEEDQILTEA LVGLSGLEVQ RSGPQYTWNP 
       430        440    
DTCHNLCALY AGLSLLHLLS RDS         10         20         30         40         50         60 
MSMFEDVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG ARYVRTDYTL 
        70         80         90        100        110        120 
LDVLEPGSSP SDPTLLGNFS FKNMLDVRVE GDVEVPTMMK VKGTVGLSQS STLEVQMLSV 
       130        140        150        160        170        180 
APTALENLHM ERKLSADHPF LKEMREYKQN LYVVMEVVKA KQEVTLKRAS NAISKFSLNL 
       190        200        210        220        230        240 
PSLGLQGSVN HKEAVTIPKG CVLAYRVRQL IIYGKDEWGI PYICTDNMPT FNPLCVLQRQ 
       250        260        270        280        290        300 
GSTVQMISGE MHEDFKTLKK EVQQETQEVE KLSPVGRSSL LTSLSHLLGK KKELQDLEQM 
       310        320        330        340        350        360 
LEGALDKGHE VTLEALPKDV LLLKDAMDAI LYFLGALTEL SEEQLKILVK SLENKVLPVQ 
       370        380        390        400        410        420 
LKLVESILEQ NFLQDKEDVF PLRPDLLSSL GEEDQILTEA LVGLSGLEVQ RSGPQYTWNP 
       430        440    
DTCHNLCALY AGLSLLHLLS RDS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q32M21-1-unknown MSMFED... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q32M21-1-unknown MSMFED... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76550

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)