Q3SYG4: Protein PTHB1

General Information

Protein names	- Protein PTHB1 - Bardet-Biedl syndrome 9 protein - Parathyroid hormone-responsive B1 gene protein
Gene names	BBS9
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3SYG4

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein PTHB1 - Isoform 3 of Protein PTHB1 - Isoform 4 of Protein PTHB1 - Isoform 5 of Protein PTHB1 - Isoform 6 of Protein PTHB1 - Isoform 7 of Protein PTHB1

Sequence View

        10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE         10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE         10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE         10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE         10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE         10         20         30         40         50         60
MSLFKARDWW STILGDKEEF DQGCLCLANV DNSGNGQDKI IVGSFMGYLR IFSPHPAKTG
        70         80         90        100        110        120
DGAQAEDLLL EVDLRDPVLQ VEVGKFVSGT EMLHLAVLHS RKLCVYSVSG TLGNVEHGNQ
       130        140        150        160        170        180
CQMKLMYEHN LQRTACNMTY GSFGGVKGRD LICIQSMDGM LMVFEQESYA FGRFLPGFLL
       190        200        210        220        230        240
PGPLAYSSRT DSFLTVSSCQ QVESYKYQVL AFATDADKRQ ETEQQKLGSG KRLVVDWTLN
       250        260        270        280        290        300
IGEQALDICI VSFNQSASSV FVLGERNFFC LKDNGQIRFM KKLDWSPSCF LPYCSVSEGT
       310        320        330        340        350        360
INTLIGNHNN MLHIYQDVTL KWATQLPHIP VAVRVGCLHD LKGVIVTLSD DGHLQCSYLG
       370        380        390        400        410        420
TDPSLFQAPN VQSRELNYDE LDVEMKELQK IIKDVNKSQG VWPMTEREDD LNVSVVVSPN
       430        440        450        460        470        480
FDSVSQATDV EVGTDLVPSV TVKVTLQNRV ILQKAKLSVY VQPPLELTCD QFTFEFMTPD
       490        500        510        520        530        540
LTRTVSFSVY LKRSYTPSEL EGNAVVSYSR PTDRNPDGIP RVIQCKFRLP LKLICLPGQP
       550        560        570        580        590        600
SKTASHKITI DTNKSPVSLL SLFPGFASQS DDDQVNVMGF HFLGGARITV LASKTSQRYR
       610        620        630        640        650        660
IQSEQFEDLW LITNELILRL QEYFEKQGVK DFACSFSGSI PLQEYFELID HHFELRINGE
       670        680        690        700        710        720
KLEELLSERA VQFRAIQRRL LARFKDKTPA PLQHLDTLLD GTYKQVIALA DAVEENQGNL
       730        740        750        760        770        780
FQSFTRLKSA THLVILLIAL WQKLSADQVA ILEAAFLPLQ EDTQELGWEE TVDAAISHLL
       790        800        810        820        830        840
KTCLSKSSKE QALNLNSQLN IPKDTSQLKK HITLLCDRLS KGGRLCLSTD AAAPQTMVMP
       850        860        870        880
GGCTTIPESD LEERSVEQDS TELFTNHRHL TAETPRPEVS PLQGVSE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q3SYG4-1-unknown	MSLFKA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3SYG4-1-unknown	MSLFKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86462
Q3SYG4-1-unknown	MSLFKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86463
Q3SYG4-1-unknown	MSLFKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86464
Q3SYG4-1-unknown	MSLFKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86466
Q3SYG4-1-unknown	MSLFKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86467
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86465
Q3SYG4-46-unknown	MGYLRI...	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405151
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106685
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106686
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106687
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106688
Q3SYG4-46-unknown	MGYLRI...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106689
Q3SYG4-123-unknown	MKLMYE...	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000388646
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197283
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197281
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197282
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197284
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197285
Q3SYG4-123-unknown	MKLMYE...	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197286

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LHLAVL	97	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415794
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154330
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154328
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154329
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154331
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154332
...LHLAVL	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154333
...GERNFF	268	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000388646
...QGVSE	887	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QGVSE	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82080
...QGVSE	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82082
...QGVSE	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82085

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)