TopFIND 4.0

Q3T1I5: Sterol regulatory element-binding protein 2

General Information

Protein names
- Sterol regulatory element-binding protein 2
- SREBP-2
- Sterol regulatory element-binding transcription factor 2
- Processed sterol regulatory element-binding protein 2
Gene names Srebf2 {ECO:0000312|EMBL:AAI01903.1}
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3T1I5

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDENSELGGL ETMETLTELG DELTLGDIDE MLQFVSNQVG EFSDLFSEQL CSSFPGGGGG 
        70         80         90        100        110        120 
SGSGGTSNNS SGRGTSGGAA DPAVQRSFSQ VPLSTFSPSS TSPQAPALQV KVSPTPPRAT 
       130        140        150        160        170        180 
PVLQPRPQPQ PQPPAQLQQQ TVMITPTFST APQTRIIQQP LIYQNAATSF QVLQPQVQSL 
       190        200        210        220        230        240 
VTSSQVQPVT IQQQVQTVQA QRVLTQTANG TLQTLAPATV QTVATPQVQQ VPVLVQPQII 
       250        260        270        280        290        300 
KTDSLVLTTL KTDGSPVMAA VQNPALTALT APIQTAALQV PTLVGSNGAI LTTMPVMMGQ 
       310        320        330        340        350        360 
EKVPIKQVPG GVKQLEPPKE GERRTTHNII EKRYRSSIND KIIELKDLVM GTDAKMHKSG 
       370        380        390        400        410        420 
VLRKAIDYIK YLQQVNHKLR QENMVLKLAN QKNKLLKGID LGSLVDSDVD LKIDDFNQNV 
       430        440        450        460        470        480 
LLMSPPASDS GSQAGFSPYS IDSEPGSPLL DDAKVKDEPD SPPVALGMVD RSRILLCVLT 
       490        500        510        520        530        540 
FLGLSFNPLT SLLQWGGAHN PDQHPYSGSG RNVLSLESGS GGWFDWMMPT LLLWLLNGVI 
       550        560        570        580        590        600 
VLSVFVKLLV HGEPVIRPHS RSSVTFWRHR KQADLDLAKG DFAAAAANLQ TCLSVLGRAL 
       610        620        630        640        650        660 
PTSRLDLACS LSWNVIRYSL QKLRLVRWLL KKVFQRWRAT PATAAGFEDE AKSSARDAAL 
       670        680        690        700        710        720 
AYHRLHQLHI TGKLPAGSAC SDVHMALCAV NLAECAEEKI PPSTLVEIHL TAAMGLKTRC 
       730        740        750        760        770        780 
GGKLGFLASY FLNRAQSLCG PEHSAVPDSL RWLCHPLGQK FFMERSWSIK SAAKDSLYCA 
       790        800        810        820        830        840 
QRNPADPIAQ VHQAFCKHLL ERAVEALVKP QAKKKAGDRE EESCEFSSAL EFLKLLHSFV 
       850        860        870        880        890        900 
DSVGFVASPF SSSSVLRSAL GPDVVCRWWT SAITVAISWL QGDDAAVRSH FTEVERVPKA 
       910        920        930        940        950        960 
LEVTESPLVK AVFYACRAMH ASLSGKADGQ QNSFCHCERA SGHLWSSLNV SGTTSDPSLN 
       970        980        990       1000       1010       1020 
HVVQLLTCDL LLSLRTTLWQ KQASASQLLG ETYHASGTEL AGFQRDLGSL RRLAHSFRPA 
      1030       1040       1050       1060       1070       1080 
YRKVFLHEAT VRLMAGASPT RTHQLLEHSL RRRTTQNTKH GEVDTWPGQR ERATAILLAC 
      1090       1100       1110       1120       1130    
RHLPLSFLSS PGQRAVLLAE AARTLEKVGD RRSCSDCQQM IVKLGGGTAI AAS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q3T1I5-1-unknown MDENSE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SRILLC 476 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AIAAS 1133 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)