TopFIND 4.0

Q3TD49: Signal peptide peptidase-like 2B {ECO:0000250|UniProtKB:Q8TCT7}

General Information

Protein names
- Signal peptide peptidase-like 2B {ECO:0000250|UniProtKB:Q8TCT7}
- SPP-like 2B {ECO:0000250|UniProtKB:Q8TCT7}
- SPPL2b {ECO:0000250|UniProtKB:Q8TCT7}
- 3.4.23.-
Gene names Sppl2b
Organism Mus musculus
Protease Family
Protease ID A22.004
Chromosome location
UniProt ID Q3TD49

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAARLAAAL LLLAAQVACE FGVLRVVSQT SRTRSRDYCI LYNPQWAHLP HDLSKVSLLK 
        70         80         90        100        110        120 
LRDLSTTQLC SYLDVPAEDF TNQIALVARG NCTFYEKVRL AQGSGAHGLL IVSKEKLVPP 
       130        140        150        160        170        180 
GGNKTQYEEI SIPVALLSHR DLQDIFRRFG REVMVALYAP SEPVMDYNMV IIFVMAVGTV 
       190        200        210        220        230        240 
AIGGYWAGSH DVKKYMKHKR DDGPEKQEDE AVDVTPVMIC VFVVMCCFML VLLYYFYDRL 
       250        260        270        280        290        300 
VYVIIGIFCL ASSTGLYSCL APFVRKLPFC TCRVPDNNLP YFHKRPQARM LLLALFCVTV 
       310        320        330        340        350        360 
SVVWGIFRNE DQWAWVLQDT LGIAFCLYML KTIRLPTFKA CTLLLLVLFI YDIFFVFITP 
       370        380        390        400        410        420 
FLTKSGNSIM VEVATGPSNS STHEKLPMVL KVPRLNTSPL SLCDRPFSLL GFGDILVPGL 
       430        440        450        460        470        480 
LVAYCHRFDI QVQSSRIYFV ACTIAYGLGL LVTFVALVLM QRGQPALLYL VPCTLLTSCT 
       490        500        510        520        530        540 
VALWRRELGA FWTGSGFAKD APQTPWAATQ GPVPPKAVGS SLSEQPPSEE LAKSPLSTEE 
       550        560        570    
AGAADPAKDP DNPVASPLSP SNGDEAQPIP VVKPETSA

Isoforms

- Isoform 2 of Signal peptide peptidase-like 2B

Sequence View

        10         20         30         40         50         60 
MAAARLAAAL LLLAAQVACE FGVLRVVSQT SRTRSRDYCI LYNPQWAHLP HDLSKVSLLK 
        70         80         90        100        110        120 
LRDLSTTQLC SYLDVPAEDF TNQIALVARG NCTFYEKVRL AQGSGAHGLL IVSKEKLVPP 
       130        140        150        160        170        180 
GGNKTQYEEI SIPVALLSHR DLQDIFRRFG REVMVALYAP SEPVMDYNMV IIFVMAVGTV 
       190        200        210        220        230        240 
AIGGYWAGSH DVKKYMKHKR DDGPEKQEDE AVDVTPVMIC VFVVMCCFML VLLYYFYDRL 
       250        260        270        280        290        300 
VYVIIGIFCL ASSTGLYSCL APFVRKLPFC TCRVPDNNLP YFHKRPQARM LLLALFCVTV 
       310        320        330        340        350        360 
SVVWGIFRNE DQWAWVLQDT LGIAFCLYML KTIRLPTFKA CTLLLLVLFI YDIFFVFITP 
       370        380        390        400        410        420 
FLTKSGNSIM VEVATGPSNS STHEKLPMVL KVPRLNTSPL SLCDRPFSLL GFGDILVPGL 
       430        440        450        460        470        480 
LVAYCHRFDI QVQSSRIYFV ACTIAYGLGL LVTFVALVLM QRGQPALLYL VPCTLLTSCT 
       490        500        510        520        530        540 
VALWRRELGA FWTGSGFAKD APQTPWAATQ GPVPPKAVGS SLSEQPPSEE LAKSPLSTEE 
       550        560        570    
AGAADPAKDP DNPVASPLSP SNGDEAQPIP VVKPETSA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q3TD49-1-unknown MAAARL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90508
    Q3TD49-20-unknown EFGVLR... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q3TD49-20-unknown EFGVLR... 20 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112285

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PETSA 578 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)