Q3TRM8: Hexokinase-3

General Information

Protein names	- Hexokinase-3 - 2.7.1.1 - Hexokinase type III - HK III
Gene names	Hk3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3TRM8

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATIGPSGLH PGERASVCPH EGVPRPSGSL ELECLQQFKV TRTQLQQIQA SLLCSMEQAL
        70         80         90        100        110        120
KGQDSPAPSV RMLPTYVRST PHGTEQGDFL VLELGATGAS LRVLWVTLTG TKECRVEPRS
       130        140        150        160        170        180
REFVIPQEVI LGAGQQLFDF AARCLSEFLD AYPVENQGLK LGFNFSFPCH QTGLDRSTLI
       190        200        210        220        230        240
SWTKGFRCSG VEGQDVVQLL RDAIQRQGTY RIDVVAMVND TVGTMMGCEL GTRPCEVGLI
       250        260        270        280        290        300
VDTGTNACYM EEARHVAALD EDRGRTCVSI EWGSFYDEDA LGPVLTTFDS ALDRESLTPG
       310        320        330        340        350        360
AQRFEKMIGG LYLGELVRLV LVHLTQHGVL FDGCASPALL SQGCILLDHV AEMEDTATGT
       370        380        390        400        410        420
ARVHTILQDL GLSPRASDAE LVQYVCVAVC TRAAQLCAAA LAAVLSRLQH SREQQTLQVA
       430        440        450        460        470        480
VATGGRVFER HPRFLRILKE TVTLLAPNCD VSFIPSVDGG GRGVAMVTAV AARLAAHRRI
       490        500        510        520        530        540
LEETLAPFQL TLEQMTVVQA QMREAMIRGL QGEASSLRML PTYVRATPDG SERGDFLALD
       550        560        570        580        590        600
LGGTNFRVLL VRVAEGSVQI INQVYSIPEC RAQGSGQKLF DHIVDCIVDF QKRQGLSGQS
       610        620        630        640        650        660
LPLGFTFSFP CKQLGLDQGI LLNWTKGFNA SGCEGQDVVY LLREAIRRRQ AVELNVVAIV
       670        680        690        700        710        720
NDTVGTMMSC GYDDPRCEMG LIVGTGTNAC YMEELRNVAS VPGDSGLMCI NMEWGAFGDD
       730        740        750        760        770        780
GSLGTLSTRF DTSVDQASIN PGKQRFEKMI SGMYLGEIVR HILLHLTNLG VLFRGQKTQC
       790        800        810        820        830        840
LQARDIFKTK FLSEIESDSL ALRQVRAILE DLGLTLTSDD ALMVLEVCQA VSRRAAQLCG
       850        860        870        880        890        900
AGVAAVVEKI RENRGLQELT VSVGVDGTLY KLHPHFSKLV SATVRKLAPQ CTVTFLQSED
       910        920
GSGKGAALVT AVACRLTQMA HV

Isoforms

Sequence View

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Directness:

Physiological Relevance:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
Q3TRM8-1-unknown	MATIGP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3TRM8-2-Acetylation	ATIGPS...	2	acetylation-		unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q3TRM8-56-unknown	MEQALK...	56		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115227
Q3TRM8-537-unknown	LALDLG...	537		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30426

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KGQDSP	65	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119357
...ERGDFL	536	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30426
...QMAHV	922	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	536	GDFL.\|.LALD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> HXK3_MOUSE @536

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)