Q3U0J8: TBC1 domain family member 2B

General Information

Protein names	- TBC1 domain family member 2B
Gene names	Tbc1d2b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3U0J8

2 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPGAGDGVEE SCSGGEGAVP GTGSEAGAVA GREPSRLCGY LQKLSGKGPL RGYRSRWFVF
        70         80         90        100        110        120
DSRRCYLYYF KSPQDALPLG HLDIADACFS YQGRDEAAEP GADPPTHFQV HSAGAVTVLK
       130        140        150        160        170        180
APNRELMTYW LQELQQKRWE YCNSLDMMKW DSRTSPTPGD FPKGLVARDT TDIISQHPNP
       190        200        210        220        230        240
SAEKARTVLA VEAAPGELVG DRAAHQPAPG HPNPINFYSL KQWGNELKNS MSSFRPGRGH
       250        260        270        280        290        300
SESRRTVFYT NEEWELLDPP PKDLEESLVP EERKKPMPEG SKGVASSGFP FEFGRNPYKG
       310        320        330        340        350        360
KRPLKDIIGS YKNRHSSSDP LLEGTATSSG SSGGPTKPVP EMQLQIQSQQ EELEQLKKDL
       370        380        390        400        410        420
SSQKELIRLL QQTVRSSQYD KYFTNPQISQ GVPGDTLELL HQKDEQILGL SGQLERFGLE
       430        440        450        460        470        480
KESLQQEVRT LKSKVGELNE RLGMLMETIQ AKDEVIIKLS ACEGSVSSPT LGPSSPLAIP
       490        500        510        520        530        540
ASKDQLELDR LKDSLQGYKS QNKFLNKEIL ELSALRRNAE RRERDLMAKY SSLEAKLCQV
       550        560        570        580        590        600
ESKYLILLQE MKTPVCSEEQ GPARDVIAQL LEDALQVESQ EQPEQAFVKP HLVSEFDIYG
       610        620        630        640        650        660
FRTVPDDDEE EKLVAKVRAL DLKTLYLTDN QEVSTGVKWE NYFASTMNRE MACSPELKNL
       670        680        690        700        710        720
IRAGIPHEHR SKVWKWCVDR HTRKFKDSME PDYFQTLLQK ALEKQNPASK QIELDLLRTL
       730        740        750        760        770        780
PNNKHYSSPT SEGIQKLRSV LLAFSWRNPD IGYCQGLNRL VAVALLYLDQ EDAFWCLVTI
       790        800        810        820        830        840
VEVFMPRDYY TKTLLGSQVD QRVFRDLLSE KLPRLHTHFE QYKVDYTLIT FNWFLVVFVD
       850        860        870        880        890        900
SVVSDILFKI WDSFLYEGPK VIFRFALALF KYKEEEILKL QDSMSIFKYL RYFTRTILDA
       910        920        930        940        950        960
RKLISISFGD LNPFPLRQIR NRRAYHLEKV RLELTELEAI REDFLRERDT SPDKGELVSD

EEEDT

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q3U0J8-1-unknown	MPGAGD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q3U0J8-190-unknown	AVEAAP...	190		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30429

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DIISQH	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116348
...ARTVLA	189	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30429
...HSESRR	244	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118947
...EEEDT	965	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	189	TVLA.\|.AVEA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBD2B_MOUSE @189

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)