TopFIND 4.0

Q3U1T9: DENN domain-containing protein 1B {ECO:0000312|MGI:MGI:2447812}

General Information

Protein names
- DENN domain-containing protein 1B {ECO:0000312|MGI:MGI:2447812}
- Connecdenn 2 {ECO:0000250|UniProtKB:Q6P3S1}
Gene names Dennd1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3U1T9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDRRTRENPE RTFDLVLKVK CHASENEDPE VLWKFPEDFG DQEVLQSVPK FCFPFDVERV 
        70         80         90        100        110        120 
SQNQVGQHFT FVLTDMESKQ RFGFCRLTSG GRICLCILSY LPWFEVYYKL LNTLADYLAK 
       130        140        150        160        170        180 
ELEEDLNETL KSLYNHPVPK ANTPVNLSVH SCFITPDITG LPTIPESRNL TEYFVAVDVN 
       190        200        210        220        230        240 
NMLRLYASML HERRIIITSS KLSTLTACLH GSAALLYPMY WQHIYIPVLP PHLLDYCCAP 
       250        260        270        280        290        300 
MPYLIGIHSS LIERVKNKSL EDVVVLNVDT NTLESPFNDL SSLPSDVVSA LKNKLKKQST 
       310        320        330        340        350        360 
ATGDGVARAF LRAQAALFGS YRDALRYKPG EPITFCEESF VKHRSSVMKQ FLETAVNLQL 
       370        380        390        400        410        420 
FKQFIDGRLA KLNAGRGFSD IFEEEITSGG FCGGSPRSYQ QWVYTVKKGG ALFNTAVTKA 
       430        440        450        460        470        480 
TPAVRTAYKF AKSHARLGLK EVKSRLKHKD NEEEYGTCSG LVQYTPVYTL HNEKGENREK 
       490        500        510        520        530        540 
HKLSQTHLKR PHKSLDGTLY DDDDDDDDIE RASKISSEDG EETRAYFYES DDSVEAQVKA 
       550        560        570        580        590        600 
PYSGEMDLLG EILDTLSTHS SDQGKLAPAK SLDFFRSMDD IDYKPTNKSN APSENNLALL 
       610        620        630        640        650        660 
CASGDQGEWN LGQDDSALHG RQLPPSPRKR VSSGGLTESL FILKEESREK PLCADSVSGP 
       670        680        690        700        710        720 
TVVGKPAPTS GLRSQPAAPE ASQTERGRAE VKQTPGQAPL QSEDLSVPGP GSRQSTFVPW 
       730        740        750        760    
EKAGKEDTKP SKDVGLLQEV VSLCHMSCDF QQDLNISEES RSGNQT

Isoforms

- Isoform 2 of DENN domain-containing protein 1B - Isoform 3 of DENN domain-containing protein 1B - Isoform 4 of DENN domain-containing protein 1B - Isoform 1 of DENN domain-containing protein 1B

Sequence View

        10         20         30         40         50         60 
MDRRTRENPE RTFDLVLKVK CHASENEDPE VLWKFPEDFG DQEVLQSVPK FCFPFDVERV 
        70         80         90        100        110        120 
SQNQVGQHFT FVLTDMESKQ RFGFCRLTSG GRICLCILSY LPWFEVYYKL LNTLADYLAK 
       130        140        150        160        170        180 
ELEEDLNETL KSLYNHPVPK ANTPVNLSVH SCFITPDITG LPTIPESRNL TEYFVAVDVN 
       190        200        210        220        230        240 
NMLRLYASML HERRIIITSS KLSTLTACLH GSAALLYPMY WQHIYIPVLP PHLLDYCCAP 
       250        260        270        280        290        300 
MPYLIGIHSS LIERVKNKSL EDVVVLNVDT NTLESPFNDL SSLPSDVVSA LKNKLKKQST 
       310        320        330        340        350        360 
ATGDGVARAF LRAQAALFGS YRDALRYKPG EPITFCEESF VKHRSSVMKQ FLETAVNLQL 
       370        380        390        400        410        420 
FKQFIDGRLA KLNAGRGFSD IFEEEITSGG FCGGSPRSYQ QWVYTVKKGG ALFNTAVTKA 
       430        440        450        460        470        480 
TPAVRTAYKF AKSHARLGLK EVKSRLKHKD NEEEYGTCSG LVQYTPVYTL HNEKGENREK 
       490        500        510        520        530        540 
HKLSQTHLKR PHKSLDGTLY DDDDDDDDIE RASKISSEDG EETRAYFYES DDSVEAQVKA 
       550        560        570        580        590        600 
PYSGEMDLLG EILDTLSTHS SDQGKLAPAK SLDFFRSMDD IDYKPTNKSN APSENNLALL 
       610        620        630        640        650        660 
CASGDQGEWN LGQDDSALHG RQLPPSPRKR VSSGGLTESL FILKEESREK PLCADSVSGP 
       670        680        690        700        710        720 
TVVGKPAPTS GLRSQPAAPE ASQTERGRAE VKQTPGQAPL QSEDLSVPGP GSRQSTFVPW 
       730        740        750        760    
EKAGKEDTKP SKDVGLLQEV VSLCHMSCDF QQDLNISEES RSGNQT         10         20         30         40         50         60 
MDRRTRENPE RTFDLVLKVK CHASENEDPE VLWKFPEDFG DQEVLQSVPK FCFPFDVERV 
        70         80         90        100        110        120 
SQNQVGQHFT FVLTDMESKQ RFGFCRLTSG GRICLCILSY LPWFEVYYKL LNTLADYLAK 
       130        140        150        160        170        180 
ELEEDLNETL KSLYNHPVPK ANTPVNLSVH SCFITPDITG LPTIPESRNL TEYFVAVDVN 
       190        200        210        220        230        240 
NMLRLYASML HERRIIITSS KLSTLTACLH GSAALLYPMY WQHIYIPVLP PHLLDYCCAP 
       250        260        270        280        290        300 
MPYLIGIHSS LIERVKNKSL EDVVVLNVDT NTLESPFNDL SSLPSDVVSA LKNKLKKQST 
       310        320        330        340        350        360 
ATGDGVARAF LRAQAALFGS YRDALRYKPG EPITFCEESF VKHRSSVMKQ FLETAVNLQL 
       370        380        390        400        410        420 
FKQFIDGRLA KLNAGRGFSD IFEEEITSGG FCGGSPRSYQ QWVYTVKKGG ALFNTAVTKA 
       430        440        450        460        470        480 
TPAVRTAYKF AKSHARLGLK EVKSRLKHKD NEEEYGTCSG LVQYTPVYTL HNEKGENREK 
       490        500        510        520        530        540 
HKLSQTHLKR PHKSLDGTLY DDDDDDDDIE RASKISSEDG EETRAYFYES DDSVEAQVKA 
       550        560        570        580        590        600 
PYSGEMDLLG EILDTLSTHS SDQGKLAPAK SLDFFRSMDD IDYKPTNKSN APSENNLALL 
       610        620        630        640        650        660 
CASGDQGEWN LGQDDSALHG RQLPPSPRKR VSSGGLTESL FILKEESREK PLCADSVSGP 
       670        680        690        700        710        720 
TVVGKPAPTS GLRSQPAAPE ASQTERGRAE VKQTPGQAPL QSEDLSVPGP GSRQSTFVPW 
       730        740        750        760    
EKAGKEDTKP SKDVGLLQEV VSLCHMSCDF QQDLNISEES RSGNQT         10         20         30         40         50         60 
MDRRTRENPE RTFDLVLKVK CHASENEDPE VLWKFPEDFG DQEVLQSVPK FCFPFDVERV 
        70         80         90        100        110        120 
SQNQVGQHFT FVLTDMESKQ RFGFCRLTSG GRICLCILSY LPWFEVYYKL LNTLADYLAK 
       130        140        150        160        170        180 
ELEEDLNETL KSLYNHPVPK ANTPVNLSVH SCFITPDITG LPTIPESRNL TEYFVAVDVN 
       190        200        210        220        230        240 
NMLRLYASML HERRIIITSS KLSTLTACLH GSAALLYPMY WQHIYIPVLP PHLLDYCCAP 
       250        260        270        280        290        300 
MPYLIGIHSS LIERVKNKSL EDVVVLNVDT NTLESPFNDL SSLPSDVVSA LKNKLKKQST 
       310        320        330        340        350        360 
ATGDGVARAF LRAQAALFGS YRDALRYKPG EPITFCEESF VKHRSSVMKQ FLETAVNLQL 
       370        380        390        400        410        420 
FKQFIDGRLA KLNAGRGFSD IFEEEITSGG FCGGSPRSYQ QWVYTVKKGG ALFNTAVTKA 
       430        440        450        460        470        480 
TPAVRTAYKF AKSHARLGLK EVKSRLKHKD NEEEYGTCSG LVQYTPVYTL HNEKGENREK 
       490        500        510        520        530        540 
HKLSQTHLKR PHKSLDGTLY DDDDDDDDIE RASKISSEDG EETRAYFYES DDSVEAQVKA 
       550        560        570        580        590        600 
PYSGEMDLLG EILDTLSTHS SDQGKLAPAK SLDFFRSMDD IDYKPTNKSN APSENNLALL 
       610        620        630        640        650        660 
CASGDQGEWN LGQDDSALHG RQLPPSPRKR VSSGGLTESL FILKEESREK PLCADSVSGP 
       670        680        690        700        710        720 
TVVGKPAPTS GLRSQPAAPE ASQTERGRAE VKQTPGQAPL QSEDLSVPGP GSRQSTFVPW 
       730        740        750        760    
EKAGKEDTKP SKDVGLLQEV VSLCHMSCDF QQDLNISEES RSGNQT         10         20         30         40         50         60 
MDRRTRENPE RTFDLVLKVK CHASENEDPE VLWKFPEDFG DQEVLQSVPK FCFPFDVERV 
        70         80         90        100        110        120 
SQNQVGQHFT FVLTDMESKQ RFGFCRLTSG GRICLCILSY LPWFEVYYKL LNTLADYLAK 
       130        140        150        160        170        180 
ELEEDLNETL KSLYNHPVPK ANTPVNLSVH SCFITPDITG LPTIPESRNL TEYFVAVDVN 
       190        200        210        220        230        240 
NMLRLYASML HERRIIITSS KLSTLTACLH GSAALLYPMY WQHIYIPVLP PHLLDYCCAP 
       250        260        270        280        290        300 
MPYLIGIHSS LIERVKNKSL EDVVVLNVDT NTLESPFNDL SSLPSDVVSA LKNKLKKQST 
       310        320        330        340        350        360 
ATGDGVARAF LRAQAALFGS YRDALRYKPG EPITFCEESF VKHRSSVMKQ FLETAVNLQL 
       370        380        390        400        410        420 
FKQFIDGRLA KLNAGRGFSD IFEEEITSGG FCGGSPRSYQ QWVYTVKKGG ALFNTAVTKA 
       430        440        450        460        470        480 
TPAVRTAYKF AKSHARLGLK EVKSRLKHKD NEEEYGTCSG LVQYTPVYTL HNEKGENREK 
       490        500        510        520        530        540 
HKLSQTHLKR PHKSLDGTLY DDDDDDDDIE RASKISSEDG EETRAYFYES DDSVEAQVKA 
       550        560        570        580        590        600 
PYSGEMDLLG EILDTLSTHS SDQGKLAPAK SLDFFRSMDD IDYKPTNKSN APSENNLALL 
       610        620        630        640        650        660 
CASGDQGEWN LGQDDSALHG RQLPPSPRKR VSSGGLTESL FILKEESREK PLCADSVSGP 
       670        680        690        700        710        720 
TVVGKPAPTS GLRSQPAAPE ASQTERGRAE VKQTPGQAPL QSEDLSVPGP GSRQSTFVPW 
       730        740        750        760    
EKAGKEDTKP SKDVGLLQEV VSLCHMSCDF QQDLNISEES RSGNQT



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Physiological Relevance:


Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TPAVRT 425 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)