Q3U5C8: Rho guanine nucleotide exchange factor 16

General Information

Protein names	- Rho guanine nucleotide exchange factor 16 - Ephexin-4
Gene names	Arhgef16
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3U5C8

1 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSQRHSDSSL DEKLLEYRFH AELRLDANGN PIPGLPMVRS SLKARANAAF EPDASEPLPP
        70         80         90        100        110        120
PPSPEDEEPP RPIVLSTQSP AALKMGTQQL IPKSLAVASK AKTKSPARHQ SFGAAVLSKE
       130        140        150        160        170        180
AARRNPQLFS APSFSLDDMD MDMVTTGNLR RNLRNQSYRA AMKGPGPPSS KGDSVQLGPK
       190        200        210        220        230        240
LQALAEEAAQ PPSRYPAKNK KTLGRKRAHK GSFKDDPQLY QEIRERGLNT SHESDDDILD
       250        260        270        280        290        300
EPSGPVGTQR ADTTIVVKSY RPAQLTWSQL PEVLESGVLD TLSTEERKRQ EAIFEILTSE
       310        320        330        340        350        360
FSYLHSLSIL VTEFLQSREL RATMTQTEHH HLFSNILDVM SASQKFFEAL EQRHKAQVCV
       370        380        390        400        410        420
EDISDILEDH AQHHFHPYIA YCSNEVYQQR TLQKLSNSNA AFRDVLKEIE KRPACGGLPM
       430        440        450        460        470        480
ISFLILPMQR VTRLPLLTDT LCLKTQGHPE RYKAASQALK AISKLVKQCN EGAHKMERTE
       490        500        510        520        530        540
QIYTLNMQLD FGKVKSLPLI SASRWLLKRG ELFLLEESSI FRKIASRPTC YLFLFNDVLV
       550        560        570        580        590        600
VTKKKSEESY LVQDYAQLDH VQVRKLEPSE PLLPGGSSRS SSVPYPFQVN LLHNSEGRQE
       610        620        630        640        650        660
QILLSSDSAS DRARWITALT YKERQWQGIT NKGELPQVEV TKAYFAKQAD EITLQQADIV
       670        680        690        700        710
LVLQEEDGWL HGERLRDGET GWFPESFAHS ITSRVAVEGN VRRMERLRVE TDV

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q3U5C8-2-unknown	SQRHSD...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q3U5C8-2-unknown	SQRHSD...	2		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SSKGDS	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119398
...LNTSHE	232	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121273
...VETDV	713	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)