TopFIND 4.0

Q3U827: E3 ubiquitin-protein ligase RNF180

General Information

Protein names
- E3 ubiquitin-protein ligase RNF180
- 2.3.2.27
- RING finger protein 180
- RING-type E3 ubiquitin transferase RNF180 {ECO:0000305}
Gene names Rnf180
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3U827

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKRSEESTST QSPEEQTGTL HCWRCRKCIA SSGCFMTPLE TQVVEQDRHE SVDAQNTCHL 
        70         80         90        100        110        120 
WHMNVDALPE WISCLLQKAQ WTVGKLNCPF CGARLGGFNF VSTPKCSCGQ LAAVHLCKSR 
       130        140        150        160        170        180 
TDHQAAQGGR LMRPALKHLP HPGVPSGCDK ETLLTGGGSK TRNHWLLSMA RNSNGLGRLT 
       190        200        210        220        230        240 
EALCLEVRAT YFEMKNEKLL FKASDPKCQP FVPQPDTGRC PSRASHRKSH SLDLNISEKL 
       250        260        270        280        290        300 
ILLPTLYEIH RKPTAYPRLN ETGPIDLSGL ALPCSNSSCS FQSPPSFDPN MLLHRLSVAP 
       310        320        330        340        350        360 
HETQAQRGRE CQCGLEASSV YSDHANANSL PFLMDLPSAG RSVLEASDQE EHLSQLDFLR 
       370        380        390        400        410        420 
SASFPLGTIN HRLNNRERSK LRTLRRQQRR ERWLQKQGKY SGVGLLDHMT VSNEMSTDEE 
       430        440        450        460        470        480 
TEFPEEKDSY MCAVCLDVYF NPYMCYPCHH IFCEPCLRTL AKDNPASTPC PLCRTIISRV 
       490        500        510        520        530        540 
FLQTELNNAT KTFFTKEYLK IKQSFQKSSS AKWPLPSCRK GFHLFGGFHR RAAPVTRRQF 
       550        560        570        580        590    
PHGAHRMDYL HFEDDSRGWW FDMDMVIIYI YSVNWVIGFV VFCFLCYFFF PF

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF180 - Isoform 3 of E3 ubiquitin-protein ligase RNF180 - Isoform 4 of E3 ubiquitin-protein ligase RNF180

Sequence View

        10         20         30         40         50         60 
MKRSEESTST QSPEEQTGTL HCWRCRKCIA SSGCFMTPLE TQVVEQDRHE SVDAQNTCHL 
        70         80         90        100        110        120 
WHMNVDALPE WISCLLQKAQ WTVGKLNCPF CGARLGGFNF VSTPKCSCGQ LAAVHLCKSR 
       130        140        150        160        170        180 
TDHQAAQGGR LMRPALKHLP HPGVPSGCDK ETLLTGGGSK TRNHWLLSMA RNSNGLGRLT 
       190        200        210        220        230        240 
EALCLEVRAT YFEMKNEKLL FKASDPKCQP FVPQPDTGRC PSRASHRKSH SLDLNISEKL 
       250        260        270        280        290        300 
ILLPTLYEIH RKPTAYPRLN ETGPIDLSGL ALPCSNSSCS FQSPPSFDPN MLLHRLSVAP 
       310        320        330        340        350        360 
HETQAQRGRE CQCGLEASSV YSDHANANSL PFLMDLPSAG RSVLEASDQE EHLSQLDFLR 
       370        380        390        400        410        420 
SASFPLGTIN HRLNNRERSK LRTLRRQQRR ERWLQKQGKY SGVGLLDHMT VSNEMSTDEE 
       430        440        450        460        470        480 
TEFPEEKDSY MCAVCLDVYF NPYMCYPCHH IFCEPCLRTL AKDNPASTPC PLCRTIISRV 
       490        500        510        520        530        540 
FLQTELNNAT KTFFTKEYLK IKQSFQKSSS AKWPLPSCRK GFHLFGGFHR RAAPVTRRQF 
       550        560        570        580        590    
PHGAHRMDYL HFEDDSRGWW FDMDMVIIYI YSVNWVIGFV VFCFLCYFFF PF         10         20         30         40         50         60 
MKRSEESTST QSPEEQTGTL HCWRCRKCIA SSGCFMTPLE TQVVEQDRHE SVDAQNTCHL 
        70         80         90        100        110        120 
WHMNVDALPE WISCLLQKAQ WTVGKLNCPF CGARLGGFNF VSTPKCSCGQ LAAVHLCKSR 
       130        140        150        160        170        180 
TDHQAAQGGR LMRPALKHLP HPGVPSGCDK ETLLTGGGSK TRNHWLLSMA RNSNGLGRLT 
       190        200        210        220        230        240 
EALCLEVRAT YFEMKNEKLL FKASDPKCQP FVPQPDTGRC PSRASHRKSH SLDLNISEKL 
       250        260        270        280        290        300 
ILLPTLYEIH RKPTAYPRLN ETGPIDLSGL ALPCSNSSCS FQSPPSFDPN MLLHRLSVAP 
       310        320        330        340        350        360 
HETQAQRGRE CQCGLEASSV YSDHANANSL PFLMDLPSAG RSVLEASDQE EHLSQLDFLR 
       370        380        390        400        410        420 
SASFPLGTIN HRLNNRERSK LRTLRRQQRR ERWLQKQGKY SGVGLLDHMT VSNEMSTDEE 
       430        440        450        460        470        480 
TEFPEEKDSY MCAVCLDVYF NPYMCYPCHH IFCEPCLRTL AKDNPASTPC PLCRTIISRV 
       490        500        510        520        530        540 
FLQTELNNAT KTFFTKEYLK IKQSFQKSSS AKWPLPSCRK GFHLFGGFHR RAAPVTRRQF 
       550        560        570        580        590    
PHGAHRMDYL HFEDDSRGWW FDMDMVIIYI YSVNWVIGFV VFCFLCYFFF PF         10         20         30         40         50         60 
MKRSEESTST QSPEEQTGTL HCWRCRKCIA SSGCFMTPLE TQVVEQDRHE SVDAQNTCHL 
        70         80         90        100        110        120 
WHMNVDALPE WISCLLQKAQ WTVGKLNCPF CGARLGGFNF VSTPKCSCGQ LAAVHLCKSR 
       130        140        150        160        170        180 
TDHQAAQGGR LMRPALKHLP HPGVPSGCDK ETLLTGGGSK TRNHWLLSMA RNSNGLGRLT 
       190        200        210        220        230        240 
EALCLEVRAT YFEMKNEKLL FKASDPKCQP FVPQPDTGRC PSRASHRKSH SLDLNISEKL 
       250        260        270        280        290        300 
ILLPTLYEIH RKPTAYPRLN ETGPIDLSGL ALPCSNSSCS FQSPPSFDPN MLLHRLSVAP 
       310        320        330        340        350        360 
HETQAQRGRE CQCGLEASSV YSDHANANSL PFLMDLPSAG RSVLEASDQE EHLSQLDFLR 
       370        380        390        400        410        420 
SASFPLGTIN HRLNNRERSK LRTLRRQQRR ERWLQKQGKY SGVGLLDHMT VSNEMSTDEE 
       430        440        450        460        470        480 
TEFPEEKDSY MCAVCLDVYF NPYMCYPCHH IFCEPCLRTL AKDNPASTPC PLCRTIISRV 
       490        500        510        520        530        540 
FLQTELNNAT KTFFTKEYLK IKQSFQKSSS AKWPLPSCRK GFHLFGGFHR RAAPVTRRQF 
       550        560        570        580        590    
PHGAHRMDYL HFEDDSRGWW FDMDMVIIYI YSVNWVIGFV VFCFLCYFFF PF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FFFPF 592 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...FFFPF 592 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83545

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)