TopFIND 4.0

Q3UFK8: FERM domain-containing protein 8

General Information

Protein names
- FERM domain-containing protein 8
- iRhom tail-associated protein {ECO:0000303|PubMed:29897333}
- iTAP {ECO:0000303|PubMed:29897333}

Gene names Frmd8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3UFK8

2

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEGAEGNAGQ PGPAERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLS SISAHELHRA 
        70         80         90        100        110        120 
VREVLQLPDV ALEAFALWLV SPLLEVQLKP KHQPYKLGRQ WPELLLRFTN ASDDDVAMDE 
       130        140        150        160        170        180 
PSLQFRRNVF FPRRRELQIH DEEVLRLLYE EAKGNVLTAR YPCDLEDCEV LGGLVCRVQL 
       190        200        210        220        230        240 
GPYQPGQPAA CTLREKLDSF LPAHLCKRGH GLFAAFRGRG AKTGPGEQGL LNAYRQVKEV 
       250        260        270        280        290        300 
TGNNSEREAT LGSHYRAYLL KCHELPFYGC AFFHGEVDKP AQGFLHRGGR KPVTVAISLE 
       310        320        330        340        350        360 
GVHVIDNREK HVLLGLRFQE LSWDHTSPEE EEPVLWLEFD GDSEGTPVNK LLRIYSKQAE 
       370        380        390        400        410        420 
LMSGLIEYCI ELSQAAEPTL SQESASGPHE APSPSPPPTQ RPKLRRQGSV VCSRIQHLST 
       430        440        450        460    
IDYVEDGKGI KRVKPKRTTS FFSRQLSSSQ GSYTVVQPTD DSLEQS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q3UFK8-1-Acetylation MEGAEG... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q3UFK8-423-unknown YVEDGK... 423 inferred from cleavage unknown TopFIND Inferred from cleavage TC30431

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)