TopFIND 4.0

Q3UIK4: N6-adenosine-methyltransferase non-catalytic subunit

General Information

Protein names
- N6-adenosine-methyltransferase non-catalytic subunit
- Methyltransferase-like protein 14
Gene names Mettl14
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3UIK4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDSRLQEIRE RQKLRRQLLA QQLGAESADS IGAVLNSKDE QREIAETRET CRASYDTSAP 
        70         80         90        100        110        120 
NSKRKCLDEG ETDEDKVEEY KDELEMQQEE ENLPYEEEIY KDSSTFLKGT QSLNPHNDYC 
       130        140        150        160        170        180 
QHFVDTGHRP QNFIRDVGLA DRFEEYPKLR ELIRLKDELI AKSNTPPMYL QADIEAFDIR 
       190        200        210        220        230        240 
ELTPKFDVIL LEPPLEEYYR ETGITANEKC WTWDDIMKLE IDEIAAPRSF IFLWCGSGEG 
       250        260        270        280        290        300 
LDLGRVCLRK WGYRRCEDIC WIKTNKNNPG KTKTLDPKAV FQRTKEHCLM GIKGTVKRST 
       310        320        330        340        350        360 
DGDFIHANVD IDLIITEEPE IGNIEKPVEI FHIIEHFCLG RRRLHLFGRD STIRPGWLTV 
       370        380        390        400        410        420 
GPTLTNSNYN AETYASYFSA PNSYLTGCTE EIERLRPKSP PPKSKSDRGG GAPRGGGRGG 
       430        440        450    
TSAGRGRERN RSNFRGERGG FRGGRGGTHR GGFTPR

Isoforms

- Isoform 2 of N6-adenosine-methyltransferase subunit METTL14 - Isoform 2 of N6-adenosine-methyltransferase non-catalytic subunit

Sequence View

        10         20         30         40         50         60 
MDSRLQEIRE RQKLRRQLLA QQLGAESADS IGAVLNSKDE QREIAETRET CRASYDTSAP 
        70         80         90        100        110        120 
NSKRKCLDEG ETDEDKVEEY KDELEMQQEE ENLPYEEEIY KDSSTFLKGT QSLNPHNDYC 
       130        140        150        160        170        180 
QHFVDTGHRP QNFIRDVGLA DRFEEYPKLR ELIRLKDELI AKSNTPPMYL QADIEAFDIR 
       190        200        210        220        230        240 
ELTPKFDVIL LEPPLEEYYR ETGITANEKC WTWDDIMKLE IDEIAAPRSF IFLWCGSGEG 
       250        260        270        280        290        300 
LDLGRVCLRK WGYRRCEDIC WIKTNKNNPG KTKTLDPKAV FQRTKEHCLM GIKGTVKRST 
       310        320        330        340        350        360 
DGDFIHANVD IDLIITEEPE IGNIEKPVEI FHIIEHFCLG RRRLHLFGRD STIRPGWLTV 
       370        380        390        400        410        420 
GPTLTNSNYN AETYASYFSA PNSYLTGCTE EIERLRPKSP PPKSKSDRGG GAPRGGGRGG 
       430        440        450    
TSAGRGRERN RSNFRGERGG FRGGRGGTHR GGFTPR         10         20         30         40         50         60 
MDSRLQEIRE RQKLRRQLLA QQLGAESADS IGAVLNSKDE QREIAETRET CRASYDTSAP 
        70         80         90        100        110        120 
NSKRKCLDEG ETDEDKVEEY KDELEMQQEE ENLPYEEEIY KDSSTFLKGT QSLNPHNDYC 
       130        140        150        160        170        180 
QHFVDTGHRP QNFIRDVGLA DRFEEYPKLR ELIRLKDELI AKSNTPPMYL QADIEAFDIR 
       190        200        210        220        230        240 
ELTPKFDVIL LEPPLEEYYR ETGITANEKC WTWDDIMKLE IDEIAAPRSF IFLWCGSGEG 
       250        260        270        280        290        300 
LDLGRVCLRK WGYRRCEDIC WIKTNKNNPG KTKTLDPKAV FQRTKEHCLM GIKGTVKRST 
       310        320        330        340        350        360 
DGDFIHANVD IDLIITEEPE IGNIEKPVEI FHIIEHFCLG RRRLHLFGRD STIRPGWLTV 
       370        380        390        400        410        420 
GPTLTNSNYN AETYASYFSA PNSYLTGCTE EIERLRPKSP PPKSKSDRGG GAPRGGGRGG 
       430        440        450    
TSAGRGRERN RSNFRGERGG FRGGRGGTHR GGFTPR



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q3UIK4-1-unknown MDSRLQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q3UIK4-1-unknown MDSRLQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80922

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GFTPR 456 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)