Q3UMT1: Protein phosphatase 1 regulatory subunit 12C

General Information

Protein names	- Protein phosphatase 1 regulatory subunit 12C - Protein phosphatase 1 myosin-binding subunit of 85 kDa - Protein phosphatase 1 myosin-binding subunit p85
Gene names	Ppp1r12c
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3UMT1

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGEDGPAAG PGAAAAAAAA RERRQEQLRQ WGARAGADPG PGERRARTVR FERAAEFLAA
        70         80         90        100        110        120
CAGGDLDEAR LMLRAADPGP GSGAASDPAV PPPARAVLDS TNADGISALH QACIDENLEV
       130        140        150        160        170        180
VRFLVEQGAT VNQADNEGWT PLHVAASCGY LDIARYLLSH GANIAAVNSD GDLPLDLAES
       190        200        210        220        230        240
DAMEGLLKAE ITRRGVDVEA AKRAEEELLL HDTRCWLNGG AMPEARHPRT GASALHVAAA
       250        260        270        280        290        300
KGYIEVMRLL LQAGYDTELR DGDGWTPLHA AAHWGVEDAC RLLAEHGGGM DSLTHAGQRP
       310        320        330        340        350        360
CDLADEDVMN LLEELAQKQE DLRNQKEGSQ GRGQESQVPS SSKHRRSSVC RLSSREKISL
       370        380        390        400        410        420
QDLSKERRPG GAGGPPIGDE DEGGEASAEH PAVEPRALNG VSSPVSSNPK SPVLPEEAPF
       430        440        450        460        470        480
SRRFGLQKTG STGALGPSER RATEGVLGLQ RSASSSLLEK ASTQAREPRL ARITPTPAQK
       490        500        510        520        530        540
VPEPFTLYEA ATPPSLDHSV PPSRREPGSI VKPNVLTASA APLADSRDRR RSYQMPVRDE
       550        560        570        580        590        600
ESESQRKARS RLMRQSRRST QGVTLTDLKE AEKVAGKVPE PEQPALPSLD PSRRPRVPGV
       610        620        630        640        650        660
ENAEGPAQRE APEGQGQGPQ AAREHRKAGH ERRGPAEGEE AGPAERSPEC STVDGGSQVR
       670        680        690        700        710        720
RQHSQRDLVL ESKQEHEEPD GGFRKMYTEL RRENERLREA LTETTLRLAQ LKVELERATQ
       730        740        750        760        770        780
RQERFAERPA LLELERFERR ALERKAAELE EELKALSDLR ADNQRLKDEN AALIRVISKL

SK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q3UMT1-2-unknown	MSGEDG...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q3UMT1-2-unknown	MSGEDG...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3UMT1-2-Acetylation	SGEDGP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3UMT1-2-Acetylation	SGEDGP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q3UMT1-80-unknown	PGSGAA...	80		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120029
Q3UMT1-458-unknown	LEKAST...	458		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30433

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ASSSLL	457	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30433
	...SKLSK	782	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	457	SSLL.\|.LEKA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PP12C_MOUSE @457

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)