TopFIND 4.0

Q3UMW7: MAP kinase-activated protein kinase 3

General Information

Protein names
- MAP kinase-activated protein kinase 3
- MAPK-activated protein kinase 3
- MAPKAP kinase 3
- MAPKAP-K3
- MAPKAPK-3
- MK-3
- 2.7.11.1
Gene names Mapkapk3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3UMW7

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDGETAGEKG SLVPPPGALG GSALGGAPAP GVRREPKKYA VTDDYQLSKQ VLGLGVNGKV 
        70         80         90        100        110        120 
LECYHRRSGQ KCALKLLYDS PKARQEVDHH WQASGGPHIV RILDVYENMH HGKRCLLIVM 
       130        140        150        160        170        180 
ECMEGGELFS RIQERGDQAF TEREAAEIMR DIGTAIQFLH SRNIAHRDVK PENLLYTSKE 
       190        200        210        220        230        240 
KDAVLKLTDF GFAKETTQNA LQTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG 
       250        260        270        280        290        300 
FPPFYSNTGQ AISPGMKRRI RLGQYSFPNP EWLDVSEDAK QLIRLLLKTD PTERLTIMQF 
       310        320        330        340        350        360 
MNHPWINQSM VVPQTPLYTA RVLQEDKDHW DDVKEEMTSA LATMRVDYDQ VKIKDLKTSN 
       370        380    
NRLLNKRRKK QAGSSSASQG CNNQ

Isoforms

- Isoform 2 of MAP kinase-activated protein kinase 3 - Isoform 3 of MAP kinase-activated protein kinase 3

Sequence View

        10         20         30         40         50         60 
MDGETAGEKG SLVPPPGALG GSALGGAPAP GVRREPKKYA VTDDYQLSKQ VLGLGVNGKV 
        70         80         90        100        110        120 
LECYHRRSGQ KCALKLLYDS PKARQEVDHH WQASGGPHIV RILDVYENMH HGKRCLLIVM 
       130        140        150        160        170        180 
ECMEGGELFS RIQERGDQAF TEREAAEIMR DIGTAIQFLH SRNIAHRDVK PENLLYTSKE 
       190        200        210        220        230        240 
KDAVLKLTDF GFAKETTQNA LQTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG 
       250        260        270        280        290        300 
FPPFYSNTGQ AISPGMKRRI RLGQYSFPNP EWLDVSEDAK QLIRLLLKTD PTERLTIMQF 
       310        320        330        340        350        360 
MNHPWINQSM VVPQTPLYTA RVLQEDKDHW DDVKEEMTSA LATMRVDYDQ VKIKDLKTSN 
       370        380    
NRLLNKRRKK QAGSSSASQG CNNQ         10         20         30         40         50         60 
MDGETAGEKG SLVPPPGALG GSALGGAPAP GVRREPKKYA VTDDYQLSKQ VLGLGVNGKV 
        70         80         90        100        110        120 
LECYHRRSGQ KCALKLLYDS PKARQEVDHH WQASGGPHIV RILDVYENMH HGKRCLLIVM 
       130        140        150        160        170        180 
ECMEGGELFS RIQERGDQAF TEREAAEIMR DIGTAIQFLH SRNIAHRDVK PENLLYTSKE 
       190        200        210        220        230        240 
KDAVLKLTDF GFAKETTQNA LQTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG 
       250        260        270        280        290        300 
FPPFYSNTGQ AISPGMKRRI RLGQYSFPNP EWLDVSEDAK QLIRLLLKTD PTERLTIMQF 
       310        320        330        340        350        360 
MNHPWINQSM VVPQTPLYTA RVLQEDKDHW DDVKEEMTSA LATMRVDYDQ VKIKDLKTSN 
       370        380    
NRLLNKRRKK QAGSSSASQG CNNQ



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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)