TopFIND 4.0

Q3UTH8: Rho guanine nucleotide exchange factor 9

General Information

Protein names
- Rho guanine nucleotide exchange factor 9
- Collybistin
- Rac/Cdc42 guanine nucleotide exchange factor 9
Gene names Arhgef9
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q3UTH8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MYDLITGDSI VSAEAVWDHV TMANRELAFK AGDVIKVLDA SNKDWWWGQI DDEEGWFPAS 
        70         80         90        100        110        120 
FVRLWVNQED GVEEGPSDVQ NGHLDPNSDC LCLGRPLQNR DQMRANVINE IMSTERHYIK 
       130        140        150        160        170        180 
HLKDICEGYL KQCRKRRDMF SDEQLKVIFG NIEDIYRFQM GFVRDLEKQY NNDDPHLSEI 
       190        200        210        220        230        240 
GPCFLEHQDG FWIYSEYCNN HLDACMELSK LMKDSRYQHF FEACRLLQQM IDIAIDGFLL 
       250        260        270        280        290        300 
TPVQKICKYP LQLAELLKYT AQDHSDYRYV AAALAVMRNV TQQINERKRR LENIDKIAQW 
       310        320        330        340        350        360 
QASVLDWEGE DILDRSSELI YTGEMAWIYQ PYGRNQQRVF FLFDHQMVLC KKDLIRRDIL 
       370        380        390        400        410        420 
YYKGRIDMDK YEVIDIEDGR DDDFNVSMKN AFKLHNKETE EVHLFFAKKL EEKIRWLRAF 
       430        440        450        460        470        480 
REERKMVQED EKIGFEISEN QKRQAAMTVR KASKQKGVNS ARSVPPSYPP PQDPLNQGQY 
       490        500        510    
LVPDGIAQSQ VFEFTEPKRS QSPFWQNFSR LTPFKK

Isoforms

- Isoform 2 of Rho guanine nucleotide exchange factor 9 - Isoform 3 of Rho guanine nucleotide exchange factor 9 - Isoform 4 of Rho guanine nucleotide exchange factor 9

Sequence View

        10         20         30         40         50         60 
MYDLITGDSI VSAEAVWDHV TMANRELAFK AGDVIKVLDA SNKDWWWGQI DDEEGWFPAS 
        70         80         90        100        110        120 
FVRLWVNQED GVEEGPSDVQ NGHLDPNSDC LCLGRPLQNR DQMRANVINE IMSTERHYIK 
       130        140        150        160        170        180 
HLKDICEGYL KQCRKRRDMF SDEQLKVIFG NIEDIYRFQM GFVRDLEKQY NNDDPHLSEI 
       190        200        210        220        230        240 
GPCFLEHQDG FWIYSEYCNN HLDACMELSK LMKDSRYQHF FEACRLLQQM IDIAIDGFLL 
       250        260        270        280        290        300 
TPVQKICKYP LQLAELLKYT AQDHSDYRYV AAALAVMRNV TQQINERKRR LENIDKIAQW 
       310        320        330        340        350        360 
QASVLDWEGE DILDRSSELI YTGEMAWIYQ PYGRNQQRVF FLFDHQMVLC KKDLIRRDIL 
       370        380        390        400        410        420 
YYKGRIDMDK YEVIDIEDGR DDDFNVSMKN AFKLHNKETE EVHLFFAKKL EEKIRWLRAF 
       430        440        450        460        470        480 
REERKMVQED EKIGFEISEN QKRQAAMTVR KASKQKGVNS ARSVPPSYPP PQDPLNQGQY 
       490        500        510    
LVPDGIAQSQ VFEFTEPKRS QSPFWQNFSR LTPFKK         10         20         30         40         50         60 
MYDLITGDSI VSAEAVWDHV TMANRELAFK AGDVIKVLDA SNKDWWWGQI DDEEGWFPAS 
        70         80         90        100        110        120 
FVRLWVNQED GVEEGPSDVQ NGHLDPNSDC LCLGRPLQNR DQMRANVINE IMSTERHYIK 
       130        140        150        160        170        180 
HLKDICEGYL KQCRKRRDMF SDEQLKVIFG NIEDIYRFQM GFVRDLEKQY NNDDPHLSEI 
       190        200        210        220        230        240 
GPCFLEHQDG FWIYSEYCNN HLDACMELSK LMKDSRYQHF FEACRLLQQM IDIAIDGFLL 
       250        260        270        280        290        300 
TPVQKICKYP LQLAELLKYT AQDHSDYRYV AAALAVMRNV TQQINERKRR LENIDKIAQW 
       310        320        330        340        350        360 
QASVLDWEGE DILDRSSELI YTGEMAWIYQ PYGRNQQRVF FLFDHQMVLC KKDLIRRDIL 
       370        380        390        400        410        420 
YYKGRIDMDK YEVIDIEDGR DDDFNVSMKN AFKLHNKETE EVHLFFAKKL EEKIRWLRAF 
       430        440        450        460        470        480 
REERKMVQED EKIGFEISEN QKRQAAMTVR KASKQKGVNS ARSVPPSYPP PQDPLNQGQY 
       490        500        510    
LVPDGIAQSQ VFEFTEPKRS QSPFWQNFSR LTPFKK         10         20         30         40         50         60 
MYDLITGDSI VSAEAVWDHV TMANRELAFK AGDVIKVLDA SNKDWWWGQI DDEEGWFPAS 
        70         80         90        100        110        120 
FVRLWVNQED GVEEGPSDVQ NGHLDPNSDC LCLGRPLQNR DQMRANVINE IMSTERHYIK 
       130        140        150        160        170        180 
HLKDICEGYL KQCRKRRDMF SDEQLKVIFG NIEDIYRFQM GFVRDLEKQY NNDDPHLSEI 
       190        200        210        220        230        240 
GPCFLEHQDG FWIYSEYCNN HLDACMELSK LMKDSRYQHF FEACRLLQQM IDIAIDGFLL 
       250        260        270        280        290        300 
TPVQKICKYP LQLAELLKYT AQDHSDYRYV AAALAVMRNV TQQINERKRR LENIDKIAQW 
       310        320        330        340        350        360 
QASVLDWEGE DILDRSSELI YTGEMAWIYQ PYGRNQQRVF FLFDHQMVLC KKDLIRRDIL 
       370        380        390        400        410        420 
YYKGRIDMDK YEVIDIEDGR DDDFNVSMKN AFKLHNKETE EVHLFFAKKL EEKIRWLRAF 
       430        440        450        460        470        480 
REERKMVQED EKIGFEISEN QKRQAAMTVR KASKQKGVNS ARSVPPSYPP PQDPLNQGQY 
       490        500        510    
LVPDGIAQSQ VFEFTEPKRS QSPFWQNFSR LTPFKK



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)