TopFIND 4.0

Q3ZCT8: Kelch repeat and BTB domain-containing protein 12

General Information

Protein names
- Kelch repeat and BTB domain-containing protein 12
- Kelch domain-containing protein 6
Gene names KBTBD12
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q3ZCT8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MECKIEGKEK YQHSLNLLNK IQNMKELAEM IDVVLTAEGE KFPCHRLVLA AFSPYFKAMF 
        70         80         90        100        110        120 
TCGLLECNQR EVILYDITAE SVSVLLNYMY NAALEINNAN VQTVAMAAYF MQMEEVFSVC 
       130        140        150        160        170        180 
QKYMMDHMDA SNCLGIYYFA KQIGAEDLSD RSKKYLYQHF AEVSLHEEIL EIEVHQFLTL 
       190        200        210        220        230        240 
IKSDDLNISR EESILDLVLR WVNHNKELRT VHLVELLKQV RLELVNPSFL RQALRRNTML 
       250        260        270        280        290        300 
LCDADCVDII QNAFKAIKTP QQHSLNLRYG METTSLLLCI GNNSSGIRSR HRSYGDASFC 
       310        320        330        340        350        360 
YDPVSRKTYF ISSPKYGEGL GTVCTGVVME NNTIIVAGEA SASKLSRQKN KNVEIYRYHD 
       370        380        390        400        410        420 
RGNQFWEKLC TAEFRELYAL GSIHNDLYVI GGQMKIKNQY LITNCVDKYS VERDNWKRVS 
       430        440        450        460        470        480 
PLPLQLACHA VVTVNNKLYV IGGWTPQMDL PDEEPDRLSN KLLQYDPSQD QWSVRAPMKY 
       490        500        510        520        530        540 
SKYRFSTAVV NSEIYVLGGI GCVGQDKGQV RKCLDVVEIY NPDGDFWREG PPMPSPLLSL 
       550        560        570        580        590        600 
RTNSTNAGAV DGKLYVCGGF HGADRHEVIS KEILELDPWE NQWNVVAINV LMHDSYDVCL 
       610        620    
VARMNPRDLI PPPSDLVEEG NEH

Isoforms

- Isoform 2 of Kelch repeat and BTB domain-containing protein 12

Sequence View

        10         20         30         40         50         60 
MECKIEGKEK YQHSLNLLNK IQNMKELAEM IDVVLTAEGE KFPCHRLVLA AFSPYFKAMF 
        70         80         90        100        110        120 
TCGLLECNQR EVILYDITAE SVSVLLNYMY NAALEINNAN VQTVAMAAYF MQMEEVFSVC 
       130        140        150        160        170        180 
QKYMMDHMDA SNCLGIYYFA KQIGAEDLSD RSKKYLYQHF AEVSLHEEIL EIEVHQFLTL 
       190        200        210        220        230        240 
IKSDDLNISR EESILDLVLR WVNHNKELRT VHLVELLKQV RLELVNPSFL RQALRRNTML 
       250        260        270        280        290        300 
LCDADCVDII QNAFKAIKTP QQHSLNLRYG METTSLLLCI GNNSSGIRSR HRSYGDASFC 
       310        320        330        340        350        360 
YDPVSRKTYF ISSPKYGEGL GTVCTGVVME NNTIIVAGEA SASKLSRQKN KNVEIYRYHD 
       370        380        390        400        410        420 
RGNQFWEKLC TAEFRELYAL GSIHNDLYVI GGQMKIKNQY LITNCVDKYS VERDNWKRVS 
       430        440        450        460        470        480 
PLPLQLACHA VVTVNNKLYV IGGWTPQMDL PDEEPDRLSN KLLQYDPSQD QWSVRAPMKY 
       490        500        510        520        530        540 
SKYRFSTAVV NSEIYVLGGI GCVGQDKGQV RKCLDVVEIY NPDGDFWREG PPMPSPLLSL 
       550        560        570        580        590        600 
RTNSTNAGAV DGKLYVCGGF HGADRHEVIS KEILELDPWE NQWNVVAINV LMHDSYDVCL 
       610        620    
VARMNPRDLI PPPSDLVEEG NEH



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q3ZCT8-1-unknown MECKIE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGNEH 623 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EGNEH 623 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74238

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)