Q45VK7: Cytoplasmic dynein 2 heavy chain 1
| Protein names | - Cytoplasmic dynein 2 heavy chain 1 - Cytoplasmic dynein 2 heavy chain - Dynein cytoplasmic heavy chain 2 - Dynein heavy chain 11 - mDHC11 - Dynein heavy chain isotype 1B |
|---|---|
| Gene names | Dync2h1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q45VK7 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAGSLGDVRK LFLFTTTQNY FGLRPELWDQ PPLSNCPEVN NFLDDGNQML LRVQRSEAGL
70 80 90 100 110 120
AFSNTIDFDD AKDKVLVFFK LRPEVITDGN LHNNILVSSM LESPINSLYQ AVRQVFAPML
130 140 150 160 170 180
LKDQEWSRNF DPKLQNLLSE LEAGLGIVLR KSDTNLPKLK LKEDDTRGIL TPSDEFQFWI
190 200 210 220 230 240
EQAHRGSKQI SKERASYFKE LFETISREFY NLDSLSLLEV VDLVETTRDV VDDVWRQTEH
250 260 270 280 290 300
DHYPESRMLH LLDVIGGSFG RFVQKKLGSL KLWEDPYYLV KENLKAGISI CEQWVIVCSH
310 320 330 340 350 360
LTGQVWQRYV PHPWKSGKYF PETLDKLGKR LEEVLAIRTI HEKLLYFLPA SEERIVCLSR
370 380 390 400 410 420
VFEPFTGVNP VQYNPYTEPL WKAAVSQYEK IIAPAEQKIA GKLKNYISEI QDSPQQLLQA
430 440 450 460 470 480
FLKYKELVKR PTISKELMLE RETLLARLGD SAKDFRLDFE NRCRGIPGDP SGPLSGKNLS
490 500 510 520 530 540
EVVNNIVWVR QLELKVDDTI KIAEALLSDL SGFRSFHRSA EDLLDQFKLY EQEQFDDWSR
550 560 570 580 590 600
EVQSGLSDSR SGLCIEANSR IMELDPNDGA LKVHYSDRLV ILLREVRQLS ALGFVIPAKI
610 620 630 640 650 660
QQVANVAQKF CKQAIILKQV AHFYNSIDQQ MIQSQRPMML QSALAFEQII KNSKAGSGGK
670 680 690 700 710 720
SQITWDNPKE LEGYIQKLQN AAERLATENR RLRKWHTTFC EKVVILMNID LLRQQQRWKD
730 740 750 760 770 780
GLQELRTGLA TVAAQGFQAS DMRAWRQHWN HQLYKALEHQ YQVGLEALNE NLPEINVDLT
790 800 810 820 830 840
YKQGRLQFRP PFEEIRAKYY REMKRFIGIP NQFKGVGEAG DESIFSVMID RNASGFLTIY
850 860 870 880 890 900
SKAEDLFRRL SAVLHQHKEW VVIGQVDMEA LVEKNLSTVH DWEKNFKALK IKGKEVERLP
910 920 930 940 950 960
SAVKVDCLNI NCSPVKTVID DLIQKLFDLL VLSLKKSIQT HIHEIDTFVT EAMKVLTVIP
970 980 990 1000 1010 1020
QSVEEIGDTN VQYSNLQDRR PEILPLFQEA EDKNRLLRTV AGGGVETVSN LRAKWDKFEL
1030 1040 1050 1060 1070 1080
MMESHQLMIK DQIEVMKGNV KSRLQIYYQE LDKFKARWDQ LKPGDDIIET GQQNTMDQSA
1090 1100 1110 1120 1130 1140
KSIKEKKIEF DDLEVIRKKL VDDCHHFGLE EPNFSLAYSI SKDIESCAQI WALYEEFQQG
1150 1160 1170 1180 1190 1200
LQDMAKEDWI TYRAKIYLFE EFLINWHERL RKIEEHSVMT VKLQSEVDRY KMIIPILKYV
1210 1220 1230 1240 1250 1260
RGEHLSPDHW LDLFRLLGLP RGTSLEKLLF GDLLRVADTI VEKASELKDL NSRAQGEVTI
1270 1280 1290 1300 1310 1320
REALRELDLW GVGAVFSLID YEDSQNHTIK LIKDWKDIVN QVGDNRCLLQ SLKDSPYYKG
1330 1340 1350 1360 1370 1380
FEDKVSIWER KLAQLDEYLQ NLNHIQRKWV YLEPIFGRGA LPKEQTRFNK VDEDFRSIMM
1390 1400 1410 1420 1430 1440
DIRKDSRVTT LTTHAGIRNT LLTILDQLQR CQKSLNEFLE EKRSAFPRFY FIGDDDLLEI
1450 1460 1470 1480 1490 1500
LGQSTNPSVI QSHLKKLFAG INSVCFDEES KHITAMKSLE GEVVPFKSKV LLSNNVEAWL
1510 1520 1530 1540 1550 1560
NDLALEMKQT LKQLLKECVT AGRSSQGAID PSLFPSQILC LAEQIKFTED VENAIKDHSL
1570 1580 1590 1600 1610 1620
HQIEAQLVAK LERYTSVDTS SEDPGNSESG ILELKLKALI LDIIHNIDIV KQLNQVQVHT
1630 1640 1650 1660 1670 1680
TDDWAWKKQV RFYMKSDHTC YVQMVDSELQ YTYEYQGNAP KLVYTPLTDK CYLTLTQAMK
1690 1700 1710 1720 1730 1740
MGLGGNPYGP AGTGKTESVK ALGGLLGRQV LVFNCDEGID VKSMGRIFVG LVKCGAWGCF
1750 1760 1770 1780 1790 1800
DEFNRLEEAV LSAVSMQIQT IQDALKNHRT VCELLGKEVE INANSGIFIT MNPAGKGYGG
1810 1820 1830 1840 1850 1860
RQKLPDNLKQ LFRPVAMSRP DNDLIAEVIL YSEGFKDAKE LGRKLVAIFN LSRELLTPQQ
1870 1880 1890 1900 1910 1920
HYDWGLRALK TVLRGSGNLL RQLKKNSTKQ DVNENHIVVQ ALRLNTMSKF TFADCTRFDA
1930 1940 1950 1960 1970 1980
LIKDVFPGID FKEVEYDELS SALKQVFEEA NYEVIPNQMK KALELYEQLR QRTGVVIVGP
1990 2000 2010 2020 2030 2040
SGAGKSTLWR MLRAALCKIG KVVKQYTMNP KAMPRHQLLG HIDMDTREWS DGVLTNSARQ
2050 2060 2070 2080 2090 2100
VVREPQDVSS WIICDGDIDP EWIESLNSVL DDNRLLTMPS GERIQFGPNV NFVFETHDLS
2110 2120 2130 2140 2150 2160
CASPATISRM GMIFLSDEET DLNSLIKSWL RNQPLEYRSN LENWIGDYFS KALQWVLKQN
2170 2180 2190 2200 2210 2220
DYVVETSLVG TVMNGLSHLH GCKYHDQFII NLIRGLGGNL NMKSRLEFTK EVFNWARETP
2230 2240 2250 2260 2270 2280
PDSHRPMDTY YDCDRGQLAS YMLKKPESLT ADDFSNGHIL PVIQTPDMQR GLDYFKPWLS
2290 2300 2310 2320 2330 2340
SDTKQPFILV GPEGCGKGML LRYAFSQLRS TEIATIHCSA QTTSRHLLQK LSQTCMVIST
2350 2360 2370 2380 2390 2400
NTGRVYRPKD CERLVLYLKD INLPKLDKWG TSTLVAFLQQ VLTYQGFYDE NLEWVGLENI
2410 2420 2430 2440 2450 2460
QIVASMSAGG RLGRHKLTTR FTSIVRLCAI DYPEREQLQT IYGAYLEAVL HKNLKNHSIW
2470 2480 2490 2500 2510 2520
GSSSKIYLLA GSMVQVYEQV RAKFTVDEYS HYFFTPCILT QWVLGLFRYD LEGGSSNHPL
2530 2540 2550 2560 2570 2580
DYVLEIVAYE ARRLFRDKIV GVKELHLFDN ILTSVLQGDW GSDILDNMAD SFYVTWGAHH
2590 2600 2610 2620 2630 2640
VSGGKTAPGQ PLPPHGKPLG KLTSADLKDV IKKGLIHYGR DNQNLDILLF QEVLEYMSRI
2650 2660 2670 2680 2690 2700
DRVLSFPGGS LLLAGRSGVG RRTVTSLVSH MHGAVLFSPK ISRGYEPKQF RNDLKHVLQL
2710 2720 2730 2740 2750 2760
AGIEAQQVVL LLEDYQFVHP TFLEMINSLL ASGEVPGLYT LEELEPLLLP LKDQASQDGF
2770 2780 2790 2800 2810 2820
FGPVFNYFTY RIQQNLHIVL IMDSANLNFI VNCESNPALH KKCQVLWMEG WSDSSMKKIP
2830 2840 2850 2860 2870 2880
EMLFSETDGE EKYEKKRKDE KKRNSVDPDF IKSFLLIHES CKAYGATPSR YMTFLHVYSA
2890 2900 2910 2920 2930 2940
ISSSKKKELL KRQSHLQAGV SKLNEAKALV DELNRKAGEQ SILLRIKQDE ADSALQEITV
2950 2960 2970 2980 2990 3000
SMQDASEQKT ELERLKQRIA EEVVKIEERK SKIDDELKEV QPLVNEAKLA VGNIRPESLS
3010 3020 3030 3040 3050 3060
EIRSLRMPPD VIRDILEGVL RLMGIFDTSW VSMKSFLAKR GVREDIATFD ARNIPKEIRE
3070 3080 3090 3100 3110 3120
SVEELLFKNK ASFDPKNAKR ASTAAAPLAA WVKANVQYSH VLERIQPLET EQSGLELNLK
3130 3140 3150 3160 3170 3180
KTEDRKRKLE DLLNSVGQKV SELKEKFQSR TSEAAKLEAE VSKAQETIKA AEVLISQLDR
3190 3200 3210 3220 3230 3240
EHRRWNAQVA EIAEELATLP KRAQLAAAFI TYLSAAPEGL RKNCLEEWTK AAGLEKFDLR
3250 3260 3270 3280 3290 3300
RFLCTESEQL IWKSEGLPSD DLSIENALVI LQSRVCPFLI DPSSQATEWL KTHLKDSHLE
3310 3320 3330 3340 3350 3360
VINQQDSNFI TALELAVRFG KTLIIQEMDG VEPVLYPLLR RDLVAQGPRY VVQIGDKIID
3370 3380 3390 3400 3410 3420
YNEDFRLFLS TRNPNPFIPP DAASIVTEVN FTTTRSGLRG QLLALTIQHE KPDLEEQKTK
3430 3440 3450 3460 3470 3480
LLQQEEDKKI QLARLEESLL ETLATSQGNI LENKDLIESL NQTKASSALI QDSLKESYKL
3490 3500 3510 3520 3530 3540
QISLDQERDA YLPLAESASK MYFIISDLSK INNMYRFSLA SFLRLFQRAL QNKQDSENTE
3550 3560 3570 3580 3590 3600
ERIQCLVNSL KHMVYEYICR CLFKADQLMF ALHFVRGMHP ELFQENEWDT FTGVVVGDML
3610 3620 3630 3640 3650 3660
RKADSQQRIR DQLPSWIDQE RSWAVATLKI SLPSLYQTLC LEDGAFWRTY YHHSMCEQEF
3670 3680 3690 3700 3710 3720
PSILAKKVSL FQQVLVVQAL RPDRLQSAMA LFACKALGLK ELSPLPLNLK RLYKETLEIE
3730 3740 3750 3760 3770 3780
PILIIISPGA DPSQELQELA SAERSSECYH QVAMGQGQAD LAIQMLKECA RNGDWLCLKN
3790 3800 3810 3820 3830 3840
LHLVVSWLPV LEKELNTLQP KDSFRLWLTA EVHPNFTPIL LQSSLKITYE SPPGLKKNLM
3850 3860 3870 3880 3890 3900
RTYESWTPEQ ISKRDNIHRA HALFSLAWFH AACQERRNYI PQGWTKFYEF SLSDLRAGYH
3910 3920 3930 3940 3950 3960
VIDRLFDGTK DVQWEFVHGL LENSIYGGRV DNYFDLRVLQ SYLKQFFNSS IIDVLNQRNK
3970 3980 3990 4000 4010 4020
KSIFPYSISL PNSCSILDYR AVIEKLPEDD KPSFFGLPAN IARSSQRMIS SQVISQLRIL
4030 4040 4050 4060 4070 4080
GRSVTAGCKF DREIWSNELS PVLNLWKKLN QNSNLIHQKV SPPNDRQGSP ILSFIILEQF
4090 4100 4110 4120 4130 4140
NAIRLVQSVH QSLAALSKVI RGTTLLSSEV QKLASALLNQ KCPLTWQSRW EGPEDPLQYL
4150 4160 4170 4180 4190 4200
RGLVARTLAI QNWVEKAEKQ VLLADTLDLS ELFHPDTFLN ALRQETARAT GCSVDSLKFV
4210 4220 4230 4240 4250 4260
ASWKGRLQEA KLQIKISGLL LEGCSFDGNR LSENQHDSPS VSSVLPCYMG WTPQGSYGPY
4270 4280 4290 4300
SPDECISLPV YTSAERERVV TNIDVPCGGN QDQWIQCGAA LFLKNQ
Isoforms
- Isoform 2 of Cytoplasmic dynein 2 heavy chain 1 - Isoform 3 of Cytoplasmic dynein 2 heavy chain 1Sequence View
10 20 30 40 50 60
MAGSLGDVRK LFLFTTTQNY FGLRPELWDQ PPLSNCPEVN NFLDDGNQML LRVQRSEAGL
70 80 90 100 110 120
AFSNTIDFDD AKDKVLVFFK LRPEVITDGN LHNNILVSSM LESPINSLYQ AVRQVFAPML
130 140 150 160 170 180
LKDQEWSRNF DPKLQNLLSE LEAGLGIVLR KSDTNLPKLK LKEDDTRGIL TPSDEFQFWI
190 200 210 220 230 240
EQAHRGSKQI SKERASYFKE LFETISREFY NLDSLSLLEV VDLVETTRDV VDDVWRQTEH
250 260 270 280 290 300
DHYPESRMLH LLDVIGGSFG RFVQKKLGSL KLWEDPYYLV KENLKAGISI CEQWVIVCSH
310 320 330 340 350 360
LTGQVWQRYV PHPWKSGKYF PETLDKLGKR LEEVLAIRTI HEKLLYFLPA SEERIVCLSR
370 380 390 400 410 420
VFEPFTGVNP VQYNPYTEPL WKAAVSQYEK IIAPAEQKIA GKLKNYISEI QDSPQQLLQA
430 440 450 460 470 480
FLKYKELVKR PTISKELMLE RETLLARLGD SAKDFRLDFE NRCRGIPGDP SGPLSGKNLS
490 500 510 520 530 540
EVVNNIVWVR QLELKVDDTI KIAEALLSDL SGFRSFHRSA EDLLDQFKLY EQEQFDDWSR
550 560 570 580 590 600
EVQSGLSDSR SGLCIEANSR IMELDPNDGA LKVHYSDRLV ILLREVRQLS ALGFVIPAKI
610 620 630 640 650 660
QQVANVAQKF CKQAIILKQV AHFYNSIDQQ MIQSQRPMML QSALAFEQII KNSKAGSGGK
670 680 690 700 710 720
SQITWDNPKE LEGYIQKLQN AAERLATENR RLRKWHTTFC EKVVILMNID LLRQQQRWKD
730 740 750 760 770 780
GLQELRTGLA TVAAQGFQAS DMRAWRQHWN HQLYKALEHQ YQVGLEALNE NLPEINVDLT
790 800 810 820 830 840
YKQGRLQFRP PFEEIRAKYY REMKRFIGIP NQFKGVGEAG DESIFSVMID RNASGFLTIY
850 860 870 880 890 900
SKAEDLFRRL SAVLHQHKEW VVIGQVDMEA LVEKNLSTVH DWEKNFKALK IKGKEVERLP
910 920 930 940 950 960
SAVKVDCLNI NCSPVKTVID DLIQKLFDLL VLSLKKSIQT HIHEIDTFVT EAMKVLTVIP
970 980 990 1000 1010 1020
QSVEEIGDTN VQYSNLQDRR PEILPLFQEA EDKNRLLRTV AGGGVETVSN LRAKWDKFEL
1030 1040 1050 1060 1070 1080
MMESHQLMIK DQIEVMKGNV KSRLQIYYQE LDKFKARWDQ LKPGDDIIET GQQNTMDQSA
1090 1100 1110 1120 1130 1140
KSIKEKKIEF DDLEVIRKKL VDDCHHFGLE EPNFSLAYSI SKDIESCAQI WALYEEFQQG
1150 1160 1170 1180 1190 1200
LQDMAKEDWI TYRAKIYLFE EFLINWHERL RKIEEHSVMT VKLQSEVDRY KMIIPILKYV
1210 1220 1230 1240 1250 1260
RGEHLSPDHW LDLFRLLGLP RGTSLEKLLF GDLLRVADTI VEKASELKDL NSRAQGEVTI
1270 1280 1290 1300 1310 1320
REALRELDLW GVGAVFSLID YEDSQNHTIK LIKDWKDIVN QVGDNRCLLQ SLKDSPYYKG
1330 1340 1350 1360 1370 1380
FEDKVSIWER KLAQLDEYLQ NLNHIQRKWV YLEPIFGRGA LPKEQTRFNK VDEDFRSIMM
1390 1400 1410 1420 1430 1440
DIRKDSRVTT LTTHAGIRNT LLTILDQLQR CQKSLNEFLE EKRSAFPRFY FIGDDDLLEI
1450 1460 1470 1480 1490 1500
LGQSTNPSVI QSHLKKLFAG INSVCFDEES KHITAMKSLE GEVVPFKSKV LLSNNVEAWL
1510 1520 1530 1540 1550 1560
NDLALEMKQT LKQLLKECVT AGRSSQGAID PSLFPSQILC LAEQIKFTED VENAIKDHSL
1570 1580 1590 1600 1610 1620
HQIEAQLVAK LERYTSVDTS SEDPGNSESG ILELKLKALI LDIIHNIDIV KQLNQVQVHT
1630 1640 1650 1660 1670 1680
TDDWAWKKQV RFYMKSDHTC YVQMVDSELQ YTYEYQGNAP KLVYTPLTDK CYLTLTQAMK
1690 1700 1710 1720 1730 1740
MGLGGNPYGP AGTGKTESVK ALGGLLGRQV LVFNCDEGID VKSMGRIFVG LVKCGAWGCF
1750 1760 1770 1780 1790 1800
DEFNRLEEAV LSAVSMQIQT IQDALKNHRT VCELLGKEVE INANSGIFIT MNPAGKGYGG
1810 1820 1830 1840 1850 1860
RQKLPDNLKQ LFRPVAMSRP DNDLIAEVIL YSEGFKDAKE LGRKLVAIFN LSRELLTPQQ
1870 1880 1890 1900 1910 1920
HYDWGLRALK TVLRGSGNLL RQLKKNSTKQ DVNENHIVVQ ALRLNTMSKF TFADCTRFDA
1930 1940 1950 1960 1970 1980
LIKDVFPGID FKEVEYDELS SALKQVFEEA NYEVIPNQMK KALELYEQLR QRTGVVIVGP
1990 2000 2010 2020 2030 2040
SGAGKSTLWR MLRAALCKIG KVVKQYTMNP KAMPRHQLLG HIDMDTREWS DGVLTNSARQ
2050 2060 2070 2080 2090 2100
VVREPQDVSS WIICDGDIDP EWIESLNSVL DDNRLLTMPS GERIQFGPNV NFVFETHDLS
2110 2120 2130 2140 2150 2160
CASPATISRM GMIFLSDEET DLNSLIKSWL RNQPLEYRSN LENWIGDYFS KALQWVLKQN
2170 2180 2190 2200 2210 2220
DYVVETSLVG TVMNGLSHLH GCKYHDQFII NLIRGLGGNL NMKSRLEFTK EVFNWARETP
2230 2240 2250 2260 2270 2280
PDSHRPMDTY YDCDRGQLAS YMLKKPESLT ADDFSNGHIL PVIQTPDMQR GLDYFKPWLS
2290 2300 2310 2320 2330 2340
SDTKQPFILV GPEGCGKGML LRYAFSQLRS TEIATIHCSA QTTSRHLLQK LSQTCMVIST
2350 2360 2370 2380 2390 2400
NTGRVYRPKD CERLVLYLKD INLPKLDKWG TSTLVAFLQQ VLTYQGFYDE NLEWVGLENI
2410 2420 2430 2440 2450 2460
QIVASMSAGG RLGRHKLTTR FTSIVRLCAI DYPEREQLQT IYGAYLEAVL HKNLKNHSIW
2470 2480 2490 2500 2510 2520
GSSSKIYLLA GSMVQVYEQV RAKFTVDEYS HYFFTPCILT QWVLGLFRYD LEGGSSNHPL
2530 2540 2550 2560 2570 2580
DYVLEIVAYE ARRLFRDKIV GVKELHLFDN ILTSVLQGDW GSDILDNMAD SFYVTWGAHH
2590 2600 2610 2620 2630 2640
VSGGKTAPGQ PLPPHGKPLG KLTSADLKDV IKKGLIHYGR DNQNLDILLF QEVLEYMSRI
2650 2660 2670 2680 2690 2700
DRVLSFPGGS LLLAGRSGVG RRTVTSLVSH MHGAVLFSPK ISRGYEPKQF RNDLKHVLQL
2710 2720 2730 2740 2750 2760
AGIEAQQVVL LLEDYQFVHP TFLEMINSLL ASGEVPGLYT LEELEPLLLP LKDQASQDGF
2770 2780 2790 2800 2810 2820
FGPVFNYFTY RIQQNLHIVL IMDSANLNFI VNCESNPALH KKCQVLWMEG WSDSSMKKIP
2830 2840 2850 2860 2870 2880
EMLFSETDGE EKYEKKRKDE KKRNSVDPDF IKSFLLIHES CKAYGATPSR YMTFLHVYSA
2890 2900 2910 2920 2930 2940
ISSSKKKELL KRQSHLQAGV SKLNEAKALV DELNRKAGEQ SILLRIKQDE ADSALQEITV
2950 2960 2970 2980 2990 3000
SMQDASEQKT ELERLKQRIA EEVVKIEERK SKIDDELKEV QPLVNEAKLA VGNIRPESLS
3010 3020 3030 3040 3050 3060
EIRSLRMPPD VIRDILEGVL RLMGIFDTSW VSMKSFLAKR GVREDIATFD ARNIPKEIRE
3070 3080 3090 3100 3110 3120
SVEELLFKNK ASFDPKNAKR ASTAAAPLAA WVKANVQYSH VLERIQPLET EQSGLELNLK
3130 3140 3150 3160 3170 3180
KTEDRKRKLE DLLNSVGQKV SELKEKFQSR TSEAAKLEAE VSKAQETIKA AEVLISQLDR
3190 3200 3210 3220 3230 3240
EHRRWNAQVA EIAEELATLP KRAQLAAAFI TYLSAAPEGL RKNCLEEWTK AAGLEKFDLR
3250 3260 3270 3280 3290 3300
RFLCTESEQL IWKSEGLPSD DLSIENALVI LQSRVCPFLI DPSSQATEWL KTHLKDSHLE
3310 3320 3330 3340 3350 3360
VINQQDSNFI TALELAVRFG KTLIIQEMDG VEPVLYPLLR RDLVAQGPRY VVQIGDKIID
3370 3380 3390 3400 3410 3420
YNEDFRLFLS TRNPNPFIPP DAASIVTEVN FTTTRSGLRG QLLALTIQHE KPDLEEQKTK
3430 3440 3450 3460 3470 3480
LLQQEEDKKI QLARLEESLL ETLATSQGNI LENKDLIESL NQTKASSALI QDSLKESYKL
3490 3500 3510 3520 3530 3540
QISLDQERDA YLPLAESASK MYFIISDLSK INNMYRFSLA SFLRLFQRAL QNKQDSENTE
3550 3560 3570 3580 3590 3600
ERIQCLVNSL KHMVYEYICR CLFKADQLMF ALHFVRGMHP ELFQENEWDT FTGVVVGDML
3610 3620 3630 3640 3650 3660
RKADSQQRIR DQLPSWIDQE RSWAVATLKI SLPSLYQTLC LEDGAFWRTY YHHSMCEQEF
3670 3680 3690 3700 3710 3720
PSILAKKVSL FQQVLVVQAL RPDRLQSAMA LFACKALGLK ELSPLPLNLK RLYKETLEIE
3730 3740 3750 3760 3770 3780
PILIIISPGA DPSQELQELA SAERSSECYH QVAMGQGQAD LAIQMLKECA RNGDWLCLKN
3790 3800 3810 3820 3830 3840
LHLVVSWLPV LEKELNTLQP KDSFRLWLTA EVHPNFTPIL LQSSLKITYE SPPGLKKNLM
3850 3860 3870 3880 3890 3900
RTYESWTPEQ ISKRDNIHRA HALFSLAWFH AACQERRNYI PQGWTKFYEF SLSDLRAGYH
3910 3920 3930 3940 3950 3960
VIDRLFDGTK DVQWEFVHGL LENSIYGGRV DNYFDLRVLQ SYLKQFFNSS IIDVLNQRNK
3970 3980 3990 4000 4010 4020
KSIFPYSISL PNSCSILDYR AVIEKLPEDD KPSFFGLPAN IARSSQRMIS SQVISQLRIL
4030 4040 4050 4060 4070 4080
GRSVTAGCKF DREIWSNELS PVLNLWKKLN QNSNLIHQKV SPPNDRQGSP ILSFIILEQF
4090 4100 4110 4120 4130 4140
NAIRLVQSVH QSLAALSKVI RGTTLLSSEV QKLASALLNQ KCPLTWQSRW EGPEDPLQYL
4150 4160 4170 4180 4190 4200
RGLVARTLAI QNWVEKAEKQ VLLADTLDLS ELFHPDTFLN ALRQETARAT GCSVDSLKFV
4210 4220 4230 4240 4250 4260
ASWKGRLQEA KLQIKISGLL LEGCSFDGNR LSENQHDSPS VSSVLPCYMG WTPQGSYGPY
4270 4280 4290 4300
SPDECISLPV YTSAERERVV TNIDVPCGGN QDQWIQCGAA LFLKNQ
10 20 30 40 50 60
MAGSLGDVRK LFLFTTTQNY FGLRPELWDQ PPLSNCPEVN NFLDDGNQML LRVQRSEAGL
70 80 90 100 110 120
AFSNTIDFDD AKDKVLVFFK LRPEVITDGN LHNNILVSSM LESPINSLYQ AVRQVFAPML
130 140 150 160 170 180
LKDQEWSRNF DPKLQNLLSE LEAGLGIVLR KSDTNLPKLK LKEDDTRGIL TPSDEFQFWI
190 200 210 220 230 240
EQAHRGSKQI SKERASYFKE LFETISREFY NLDSLSLLEV VDLVETTRDV VDDVWRQTEH
250 260 270 280 290 300
DHYPESRMLH LLDVIGGSFG RFVQKKLGSL KLWEDPYYLV KENLKAGISI CEQWVIVCSH
310 320 330 340 350 360
LTGQVWQRYV PHPWKSGKYF PETLDKLGKR LEEVLAIRTI HEKLLYFLPA SEERIVCLSR
370 380 390 400 410 420
VFEPFTGVNP VQYNPYTEPL WKAAVSQYEK IIAPAEQKIA GKLKNYISEI QDSPQQLLQA
430 440 450 460 470 480
FLKYKELVKR PTISKELMLE RETLLARLGD SAKDFRLDFE NRCRGIPGDP SGPLSGKNLS
490 500 510 520 530 540
EVVNNIVWVR QLELKVDDTI KIAEALLSDL SGFRSFHRSA EDLLDQFKLY EQEQFDDWSR
550 560 570 580 590 600
EVQSGLSDSR SGLCIEANSR IMELDPNDGA LKVHYSDRLV ILLREVRQLS ALGFVIPAKI
610 620 630 640 650 660
QQVANVAQKF CKQAIILKQV AHFYNSIDQQ MIQSQRPMML QSALAFEQII KNSKAGSGGK
670 680 690 700 710 720
SQITWDNPKE LEGYIQKLQN AAERLATENR RLRKWHTTFC EKVVILMNID LLRQQQRWKD
730 740 750 760 770 780
GLQELRTGLA TVAAQGFQAS DMRAWRQHWN HQLYKALEHQ YQVGLEALNE NLPEINVDLT
790 800 810 820 830 840
YKQGRLQFRP PFEEIRAKYY REMKRFIGIP NQFKGVGEAG DESIFSVMID RNASGFLTIY
850 860 870 880 890 900
SKAEDLFRRL SAVLHQHKEW VVIGQVDMEA LVEKNLSTVH DWEKNFKALK IKGKEVERLP
910 920 930 940 950 960
SAVKVDCLNI NCSPVKTVID DLIQKLFDLL VLSLKKSIQT HIHEIDTFVT EAMKVLTVIP
970 980 990 1000 1010 1020
QSVEEIGDTN VQYSNLQDRR PEILPLFQEA EDKNRLLRTV AGGGVETVSN LRAKWDKFEL
1030 1040 1050 1060 1070 1080
MMESHQLMIK DQIEVMKGNV KSRLQIYYQE LDKFKARWDQ LKPGDDIIET GQQNTMDQSA
1090 1100 1110 1120 1130 1140
KSIKEKKIEF DDLEVIRKKL VDDCHHFGLE EPNFSLAYSI SKDIESCAQI WALYEEFQQG
1150 1160 1170 1180 1190 1200
LQDMAKEDWI TYRAKIYLFE EFLINWHERL RKIEEHSVMT VKLQSEVDRY KMIIPILKYV
1210 1220 1230 1240 1250 1260
RGEHLSPDHW LDLFRLLGLP RGTSLEKLLF GDLLRVADTI VEKASELKDL NSRAQGEVTI
1270 1280 1290 1300 1310 1320
REALRELDLW GVGAVFSLID YEDSQNHTIK LIKDWKDIVN QVGDNRCLLQ SLKDSPYYKG
1330 1340 1350 1360 1370 1380
FEDKVSIWER KLAQLDEYLQ NLNHIQRKWV YLEPIFGRGA LPKEQTRFNK VDEDFRSIMM
1390 1400 1410 1420 1430 1440
DIRKDSRVTT LTTHAGIRNT LLTILDQLQR CQKSLNEFLE EKRSAFPRFY FIGDDDLLEI
1450 1460 1470 1480 1490 1500
LGQSTNPSVI QSHLKKLFAG INSVCFDEES KHITAMKSLE GEVVPFKSKV LLSNNVEAWL
1510 1520 1530 1540 1550 1560
NDLALEMKQT LKQLLKECVT AGRSSQGAID PSLFPSQILC LAEQIKFTED VENAIKDHSL
1570 1580 1590 1600 1610 1620
HQIEAQLVAK LERYTSVDTS SEDPGNSESG ILELKLKALI LDIIHNIDIV KQLNQVQVHT
1630 1640 1650 1660 1670 1680
TDDWAWKKQV RFYMKSDHTC YVQMVDSELQ YTYEYQGNAP KLVYTPLTDK CYLTLTQAMK
1690 1700 1710 1720 1730 1740
MGLGGNPYGP AGTGKTESVK ALGGLLGRQV LVFNCDEGID VKSMGRIFVG LVKCGAWGCF
1750 1760 1770 1780 1790 1800
DEFNRLEEAV LSAVSMQIQT IQDALKNHRT VCELLGKEVE INANSGIFIT MNPAGKGYGG
1810 1820 1830 1840 1850 1860
RQKLPDNLKQ LFRPVAMSRP DNDLIAEVIL YSEGFKDAKE LGRKLVAIFN LSRELLTPQQ
1870 1880 1890 1900 1910 1920
HYDWGLRALK TVLRGSGNLL RQLKKNSTKQ DVNENHIVVQ ALRLNTMSKF TFADCTRFDA
1930 1940 1950 1960 1970 1980
LIKDVFPGID FKEVEYDELS SALKQVFEEA NYEVIPNQMK KALELYEQLR QRTGVVIVGP
1990 2000 2010 2020 2030 2040
SGAGKSTLWR MLRAALCKIG KVVKQYTMNP KAMPRHQLLG HIDMDTREWS DGVLTNSARQ
2050 2060 2070 2080 2090 2100
VVREPQDVSS WIICDGDIDP EWIESLNSVL DDNRLLTMPS GERIQFGPNV NFVFETHDLS
2110 2120 2130 2140 2150 2160
CASPATISRM GMIFLSDEET DLNSLIKSWL RNQPLEYRSN LENWIGDYFS KALQWVLKQN
2170 2180 2190 2200 2210 2220
DYVVETSLVG TVMNGLSHLH GCKYHDQFII NLIRGLGGNL NMKSRLEFTK EVFNWARETP
2230 2240 2250 2260 2270 2280
PDSHRPMDTY YDCDRGQLAS YMLKKPESLT ADDFSNGHIL PVIQTPDMQR GLDYFKPWLS
2290 2300 2310 2320 2330 2340
SDTKQPFILV GPEGCGKGML LRYAFSQLRS TEIATIHCSA QTTSRHLLQK LSQTCMVIST
2350 2360 2370 2380 2390 2400
NTGRVYRPKD CERLVLYLKD INLPKLDKWG TSTLVAFLQQ VLTYQGFYDE NLEWVGLENI
2410 2420 2430 2440 2450 2460
QIVASMSAGG RLGRHKLTTR FTSIVRLCAI DYPEREQLQT IYGAYLEAVL HKNLKNHSIW
2470 2480 2490 2500 2510 2520
GSSSKIYLLA GSMVQVYEQV RAKFTVDEYS HYFFTPCILT QWVLGLFRYD LEGGSSNHPL
2530 2540 2550 2560 2570 2580
DYVLEIVAYE ARRLFRDKIV GVKELHLFDN ILTSVLQGDW GSDILDNMAD SFYVTWGAHH
2590 2600 2610 2620 2630 2640
VSGGKTAPGQ PLPPHGKPLG KLTSADLKDV IKKGLIHYGR DNQNLDILLF QEVLEYMSRI
2650 2660 2670 2680 2690 2700
DRVLSFPGGS LLLAGRSGVG RRTVTSLVSH MHGAVLFSPK ISRGYEPKQF RNDLKHVLQL
2710 2720 2730 2740 2750 2760
AGIEAQQVVL LLEDYQFVHP TFLEMINSLL ASGEVPGLYT LEELEPLLLP LKDQASQDGF
2770 2780 2790 2800 2810 2820
FGPVFNYFTY RIQQNLHIVL IMDSANLNFI VNCESNPALH KKCQVLWMEG WSDSSMKKIP
2830 2840 2850 2860 2870 2880
EMLFSETDGE EKYEKKRKDE KKRNSVDPDF IKSFLLIHES CKAYGATPSR YMTFLHVYSA
2890 2900 2910 2920 2930 2940
ISSSKKKELL KRQSHLQAGV SKLNEAKALV DELNRKAGEQ SILLRIKQDE ADSALQEITV
2950 2960 2970 2980 2990 3000
SMQDASEQKT ELERLKQRIA EEVVKIEERK SKIDDELKEV QPLVNEAKLA VGNIRPESLS
3010 3020 3030 3040 3050 3060
EIRSLRMPPD VIRDILEGVL RLMGIFDTSW VSMKSFLAKR GVREDIATFD ARNIPKEIRE
3070 3080 3090 3100 3110 3120
SVEELLFKNK ASFDPKNAKR ASTAAAPLAA WVKANVQYSH VLERIQPLET EQSGLELNLK
3130 3140 3150 3160 3170 3180
KTEDRKRKLE DLLNSVGQKV SELKEKFQSR TSEAAKLEAE VSKAQETIKA AEVLISQLDR
3190 3200 3210 3220 3230 3240
EHRRWNAQVA EIAEELATLP KRAQLAAAFI TYLSAAPEGL RKNCLEEWTK AAGLEKFDLR
3250 3260 3270 3280 3290 3300
RFLCTESEQL IWKSEGLPSD DLSIENALVI LQSRVCPFLI DPSSQATEWL KTHLKDSHLE
3310 3320 3330 3340 3350 3360
VINQQDSNFI TALELAVRFG KTLIIQEMDG VEPVLYPLLR RDLVAQGPRY VVQIGDKIID
3370 3380 3390 3400 3410 3420
YNEDFRLFLS TRNPNPFIPP DAASIVTEVN FTTTRSGLRG QLLALTIQHE KPDLEEQKTK
3430 3440 3450 3460 3470 3480
LLQQEEDKKI QLARLEESLL ETLATSQGNI LENKDLIESL NQTKASSALI QDSLKESYKL
3490 3500 3510 3520 3530 3540
QISLDQERDA YLPLAESASK MYFIISDLSK INNMYRFSLA SFLRLFQRAL QNKQDSENTE
3550 3560 3570 3580 3590 3600
ERIQCLVNSL KHMVYEYICR CLFKADQLMF ALHFVRGMHP ELFQENEWDT FTGVVVGDML
3610 3620 3630 3640 3650 3660
RKADSQQRIR DQLPSWIDQE RSWAVATLKI SLPSLYQTLC LEDGAFWRTY YHHSMCEQEF
3670 3680 3690 3700 3710 3720
PSILAKKVSL FQQVLVVQAL RPDRLQSAMA LFACKALGLK ELSPLPLNLK RLYKETLEIE
3730 3740 3750 3760 3770 3780
PILIIISPGA DPSQELQELA SAERSSECYH QVAMGQGQAD LAIQMLKECA RNGDWLCLKN
3790 3800 3810 3820 3830 3840
LHLVVSWLPV LEKELNTLQP KDSFRLWLTA EVHPNFTPIL LQSSLKITYE SPPGLKKNLM
3850 3860 3870 3880 3890 3900
RTYESWTPEQ ISKRDNIHRA HALFSLAWFH AACQERRNYI PQGWTKFYEF SLSDLRAGYH
3910 3920 3930 3940 3950 3960
VIDRLFDGTK DVQWEFVHGL LENSIYGGRV DNYFDLRVLQ SYLKQFFNSS IIDVLNQRNK
3970 3980 3990 4000 4010 4020
KSIFPYSISL PNSCSILDYR AVIEKLPEDD KPSFFGLPAN IARSSQRMIS SQVISQLRIL
4030 4040 4050 4060 4070 4080
GRSVTAGCKF DREIWSNELS PVLNLWKKLN QNSNLIHQKV SPPNDRQGSP ILSFIILEQF
4090 4100 4110 4120 4130 4140
NAIRLVQSVH QSLAALSKVI RGTTLLSSEV QKLASALLNQ KCPLTWQSRW EGPEDPLQYL
4150 4160 4170 4180 4190 4200
RGLVARTLAI QNWVEKAEKQ VLLADTLDLS ELFHPDTFLN ALRQETARAT GCSVDSLKFV
4210 4220 4230 4240 4250 4260
ASWKGRLQEA KLQIKISGLL LEGCSFDGNR LSENQHDSPS VSSVLPCYMG WTPQGSYGPY
4270 4280 4290 4300
SPDECISLPV YTSAERERVV TNIDVPCGGN QDQWIQCGAA LFLKNQ
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q45VK7-1-unknown | MAGSLG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q45VK7-1-unknown | MAGSLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73416 | |||
| Q45VK7-1-unknown | MAGSLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73417 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...FLKNQ | 4306 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...FLKNQ | 4306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt69034 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|