Q495A1: T-cell immunoreceptor with Ig and ITIM domains

General Information

Protein names	- T-cell immunoreceptor with Ig and ITIM domains - V-set and immunoglobulin domain-containing protein 9 - V-set and transmembrane domain-containing protein 3
Gene names	TIGIT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q495A1

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRWCLLLIWA QGLRQAPLAS GMMTGTIETT GNISAEKGGS IILQCHLSST TAQVTQVNWE
        70         80         90        100        110        120
QQDQLLAICN ADLGWHISPS FKDRVAPGPG LGLTLQSLTV NDTGEYFCIY HTYPDGTYTG
       130        140        150        160        170        180
RIFLEVLESS VAEHGARFQI PLLGAMAATL VVICTAVIVV VALTRKKKAL RIHSVEGDLR
       190        200        210        220        230        240
RKSAGQEEWS PSAPSPPGSC VQAEAAPAGL CGEQRGEDCA ELHDYFNVLS YRSLGNCSFF

TETG

Isoforms

- Isoform 2 of T-cell immunoreceptor with Ig and ITIM domains

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q495A1-1-unknown	MRWCLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92172
Q495A1-22-unknown	MMTGTI...	22	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q495A1-22-unknown	MMTGTI...	22	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418917
Q495A1-22-unknown	MMTGTI...	22	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419706
Q495A1-22-unknown	MMTGTI...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112960

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RRKSAG	184	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419706
...QEEWSP	190	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418917
...FTETG	244	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)