TopFIND 4.0

Q49B93: Sodium-coupled monocarboxylate transporter 2

General Information

Protein names
- Sodium-coupled monocarboxylate transporter 2
- Electroneutral sodium monocarboxylate cotransporter
- Low-affinity sodium-lactate cotransporter
- Solute carrier family 5 member 12
Gene names Slc5a12
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q49B93

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRVKNFEAWD YVVFAGLFVI SSGIGVFFAI KERKKTTSRE FLVGGRQMSF GPVALSLTAS 
        70         80         90        100        110        120 
FMSAVTVLGT PAEVYRFGAS FFLFLISYVF VVFFTSELFL PVFYRSGITS TYEYLQLRFN 
       130        140        150        160        170        180 
KPVRYAATII YIVQTILYTG VVVYAPALAL NQVTGFNLWA SVFATGIVCT FYCSLGGLKA 
       190        200        210        220        230        240 
VVWTDAFQMV VMIVGFLTVL IQGSNHVGGF NNVLEKAGNG SRLHIVDFDV DPLRRHTFWT 
       250        260        270        280        290        300 
ITIGGTFTWL GVYGVNQSTI QRCISCKTEK HAKLALYFNL LGLWIIVACA VFSGLIMYSH 
       310        320        330        340        350        360 
FKDCDPWTSG VISAPDQLMP YFVMEIFATM PGLPGLFVAC AFSGTLSTVA ASINALATVT 
       370        380        390        400        410        420 
FEDFVKSCFP HLSDKLSTWI SKGLCILFGI MCTSMAVVAS LMGSVVQAAL SIHGMCGGPM 
       430        440        450        460        470        480 
LGLFTLGLVF PFVNWKGALG GLLTGITLSF WVAIGSFIYP APESKTLPLP LSTEHCVELN 
       490        500        510        520        530        540 
ITTTVAPQIS SRPVLADTWY SLSYLYFSAV GCLGCIAAGI IISFLTGKQR GKDIDPLLIR 
       550        560        570        580        590        600 
PVCNLFCFWS KKYKTLCWCG VQHDRETEQD YLDSGSAWKQ GVESGLQNGL KQDTLAQIPG 
       610    
YNPKEKSYSN SVPEKTTYF

Isoforms

- Isoform 2 of Sodium-coupled monocarboxylate transporter 2

Sequence View

        10         20         30         40         50         60 
MRVKNFEAWD YVVFAGLFVI SSGIGVFFAI KERKKTTSRE FLVGGRQMSF GPVALSLTAS 
        70         80         90        100        110        120 
FMSAVTVLGT PAEVYRFGAS FFLFLISYVF VVFFTSELFL PVFYRSGITS TYEYLQLRFN 
       130        140        150        160        170        180 
KPVRYAATII YIVQTILYTG VVVYAPALAL NQVTGFNLWA SVFATGIVCT FYCSLGGLKA 
       190        200        210        220        230        240 
VVWTDAFQMV VMIVGFLTVL IQGSNHVGGF NNVLEKAGNG SRLHIVDFDV DPLRRHTFWT 
       250        260        270        280        290        300 
ITIGGTFTWL GVYGVNQSTI QRCISCKTEK HAKLALYFNL LGLWIIVACA VFSGLIMYSH 
       310        320        330        340        350        360 
FKDCDPWTSG VISAPDQLMP YFVMEIFATM PGLPGLFVAC AFSGTLSTVA ASINALATVT 
       370        380        390        400        410        420 
FEDFVKSCFP HLSDKLSTWI SKGLCILFGI MCTSMAVVAS LMGSVVQAAL SIHGMCGGPM 
       430        440        450        460        470        480 
LGLFTLGLVF PFVNWKGALG GLLTGITLSF WVAIGSFIYP APESKTLPLP LSTEHCVELN 
       490        500        510        520        530        540 
ITTTVAPQIS SRPVLADTWY SLSYLYFSAV GCLGCIAAGI IISFLTGKQR GKDIDPLLIR 
       550        560        570        580        590        600 
PVCNLFCFWS KKYKTLCWCG VQHDRETEQD YLDSGSAWKQ GVESGLQNGL KQDTLAQIPG 
       610    
YNPKEKSYSN SVPEKTTYF



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q49B93-1-unknown MRVKNF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q49B93-1-unknown MRVKNF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88954

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KTTYF 619 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KTTYF 619 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84572

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)