Q49MI3: Ceramide kinase-like protein

General Information

Protein names	- Ceramide kinase-like protein
Gene names	CERKL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q49MI3

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ceramide kinase-like protein - Isoform 3 of Ceramide kinase-like protein - Isoform 4 of Ceramide kinase-like protein - Isoform 5 of Ceramide kinase-like protein - Isoform 7 of Ceramide kinase-like protein - Isoform 8 of Ceramide kinase-like protein - Isoform 9 of Ceramide kinase-like protein

Sequence View

        10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK         10         20         30         40         50         60
MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD
        70         80         90        100        110        120
VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI
       130        140        150        160        170        180
TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK
       190        200        210        220        230        240
EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGGHRK PLFAIHWSVQ
       250        260        270        280        290        300
RLFTGMQTLE PSVVCVGGDG SASEVAHALL LRAQKNAGME TDRILTPVRA QLPLGLIPAG
       310        320        330        340        350        360
STNVLAHSLH GVPHVITATL HIIMGHVQLV DVCTFSTAGK LLRFGFSAMF GFGGRTLALA
       370        380        390        400        410        420
EKYRWMSPNQ RRDFAVVKAL AKLKAEDCEI SFLPFNSSDD VQERRAQGSP KSDCNDQWQM
       430        440        450        460        470        480
IQGQFLNVSI MAIPCLCSVA PRGLAPNTRL NNGSMALIIA RNTSRPEFIK HLKRYASVKN
       490        500        510        520        530        540
QFNFPFVETY TVEEVKVHPR NNTGGYNPEE EEDETASENC FPWNVDGDLM EVASEVHIRL
       550
HPRLISLYGG SMEEMIPK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q49MI3-1-unknown	MPWRRR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70378
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70379
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70380
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70381
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70382
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70383
Q49MI3-1-unknown	MPWRRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70384

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DVQERR	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65999
...DVQERR	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92590
...DVQERR	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92591
...DVQERR	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92589
...DVQERR	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92592
...EMIPK	558	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EMIPK	558	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65998
...EMIPK	558	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65997
...EMIPK	558	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66002
...EMIPK	558	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65996

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)