TopFIND 4.0

Q4FZD7: Inactive serine/threonine-protein kinase PLK5

General Information

Protein names
- Inactive serine/threonine-protein kinase PLK5
- Polo-like kinase 5
- PLK-5
Gene names Plk5
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q4FZD7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPRSRRRRS RQLVATFLRD PGSGRVYRRG KLIGKGAFSR CYKLTDMSTS AVFALKVVPR 
        70         80         90        100        110        120 
GGAGRLRLRG KVEREIALHS RLRHRNIVAF HAHFADRDHV YMVLEYCSRQ SLAHVLKVRR 
       130        140        150        160        170        180 
TLTEPEVRYY LRGLVSGLRY LHQQRIVHRD LKPSNFFLNK NMEVKIGDLG LAARVGPAGR 
       190        200        210        220        230        240 
CHRVLCGTPN FQAPEVVSRN GHSCKSDIWA LGCIMYTVLT GTPPFAAAPL SEMYQNIRDG 
       250        260        270        280        290        300 
HYLEPTHLSP SARSLIARLL APDPAERPSL DHLLQDDFFS QGFTPERLPP HSCHSPPVFA 
       310        320        330        340        350        360 
FPPPLGRLFR KVGQLLLTQC RPPCPFTSKE ASGPGEEGTE PDHMEAGNEE RDPLCTEGRI 
       370        380        390        400        410        420 
HLLTLGTPRT GLAGPKGSLA LQLEVATRKL FLCLDAGPMA GQDPPGEQRP VLWAPKWVDY 
       430        440        450        460        470        480 
SLKYGFGYQL SDGGSGVLFR DGSHMALRPQ GGHVSYQPDQ GTLWTFTLRD VPSPLRAKLA 
       490        500        510        520        530        540 
VLRLFACYMQ RRLREEGTVP MPATPASPDI SLLSFIADSQ AMVMLFSNGT VQVSLKTSQT 
       550        560        570        580        590    
QLVLSGEDED LLLTLQEPGG PAVGVSYTLD VLRSHGFTLA VHHHLRHGLH LLQSV

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q4FZD7-1-unknown MEPRSR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLQSV 595 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)