TopFIND 4.0

Q4G056: Tyrosyl-DNA phosphodiesterase 1

General Information

Protein names
- Tyrosyl-DNA phosphodiesterase 1
- Tyr-DNA phosphodiesterase 1
- 3.1.4.- {ECO:0000250|UniProtKB:Q9NUW8}
Gene names Tdp1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q4G056

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQESSYGKW TISSSDDSED EKPKPVKPST SSGPQAGQGV SKEPTYTCSE ARKAAHKRQI 
        70         80         90        100        110        120 
SPVKFNNTDS VLPHKKQKMD SPEGLGWCLS SSDDEQQPDV TQQEQPKGVP PQEKKYAPSA 
       130        140        150        160        170        180 
NVTTAQKVED RSPPDSHRAQ RADEEYETSG EGQDIWDMLD KENPFQFYLT RVSGIKAKYN 
       190        200        210        220        230        240 
SKALHIKDIL SPLFGTLVSS AQFNYCFDVN WLIKQYPPEF RKKPILLVHG DKREAKADLH 
       250        260        270        280        290        300 
AQAKPYANIS LCQAKLDIAF GTHHTKMMLL LYEEGLRVVI HTSNLIREDW HQKTQGIWLS 
       310        320        330        340        350        360 
PLYPRIYQGN HTSGESSTHF KADLTSYLMA YNAPPLQEWI DIIQEHDLSE TNVYLIGSTP 
       370        380        390        400        410        420 
GRFQGSHKDN WGHFRLRKLL QAHAPSAPRG ECWPVVGQFS SIGSLGPDES KWLCSEFKES 
       430        440        450        460        470        480 
LLAVREEGRT PGRSAVPLHL IYPSVENVRT SLEGYPAGGS LPYGIQTAEK QRWLHPYFHK 
       490        500        510        520        530        540 
WSAETSGRSN AMPHIKTYMR PSPDFSKLAW FLVTSANLSK AAWGALEKNG AQLMIRSYEL 
       550        560        570        580        590        600 
GVLFLPSAFG LDTFKVKQKF FSSSSEPMAS FPVPYDLPPE LYGSKDRPWI WNIPYVKAPD 
   
THGNMWVPS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q4G056-1-unknown MSQESS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MWVPS 609 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)