Q4JDL3: Tyrosine-protein phosphatase non-receptor type 20

General Information

Protein names	- Tyrosine-protein phosphatase non-receptor type 20 - hPTPN20 - 3.1.3.48
Gene names	PTPN20B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q4JDL3

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 3 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 4 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 5 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 6 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 7 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 8 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 9 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 10 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 11 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 12 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 13 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 14 of Tyrosine-protein phosphatase non-receptor type 20 - Isoform 15 of Tyrosine-protein phosphatase non-receptor type 20

Sequence View

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

        10         20         30         40         50         60
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN
        70         80         90        100        110        120
FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS
       130        140        150        160        170        180
EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ
       190        200        210        220        230        240
PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW
       250        260        270        280        290        300
QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF
       310        320        330        340        350        360
QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT
       370        380        390        400        410        420
GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q4JDL3-1-unknown	MSSPRD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q4JDL3-1-unknown	MSSPRD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86502
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86499
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86500
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86504
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108541
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108539
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108542
Q4JDL3-82-unknown	MWTARG...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108540

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLTLD	420	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LLTLD	420	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82118
...LLTLD	420	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82119
...LLTLD	420	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82117
...LLTLD	420	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82116
...LLTLD	420	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82115

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)