Q4KWH5: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

General Information

Protein names	- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 - 3.1.4.11 - Phosphoinositide phospholipase C-eta-1 - Phospholipase C-eta-1 - PLC-eta-1 - Phospholipase C-like protein 3 - PLC-L3
Gene names	Plch1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q4KWH5

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADLEVYKNL SPEKVERCMS VMQSGTQMIK LKRGTKGLVR LFYLDEHRTR LRWRPSRKSE
        70         80         90        100        110        120
KAKILIDSIY KVTEGRQSEI FHRQAEGNFD PSCCFTIYHG NHMESLDLIT SNPEEARTWI
       130        140        150        160        170        180
TGLKYLMAGI SDEDSLAKRQ RTHDQWVKQT FEEADKNGDG LLNIEEIHQL MHKLNVNLPR
       190        200        210        220        230        240
RKVRQMFQEA DTDENQGTLT FEEFCVFYKM MSLRRDLYLL LLSYSDKKDH LTVEELAQFL
       250        260        270        280        290        300
KVEQKMSNVT LDYCLDIIMK FEVSEENKVK NVLGIEGFTN FMRSPACDVF NPLHHEVYQD
       310        320        330        340        350        360
MDQPLCNYYI ASSHNTYLTG DQLLSQSKVD MYARVLQEGC RCVEVDCWDG PDGEPVVHHG
       370        380        390        400        410        420
YTLTSKILFR DVVETINKHA FVKNEFPVIL SIENHCSIQQ QRKIAQYLKG ILQDKLDLSS
       430        440        450        460        470        480
VDTGECRQLP SPQSLKGKIL VKGKKLPYHL GDDAEEGEVS DEDSADEIED ECKFKLHYSN
       490        500        510        520        530        540
GTTEHQVESF IRKKLESLLK ESQIRDKEDP DSFTVRALLK ATHEGLNAHL KQNLDVKESG
       550        560        570        580        590        600
KKSHGRSLMA NFGKHKQKAT KSRSKSYSTD DEDDSLQNPG KEGGQLYRLG RRRRTMKLCR
       610        620        630        640        650        660
ELSDLVVYTN SVAAQDIVDD GTTGNVLSFS ETRAHQVVQQ KSEQFMIYNQ KQLTRIYPSA
       670        680        690        700        710        720
YRIDSSNFNP LPYWNAGCQL VALNYQSEGR MMQINRAKFK ANGNCGYILK PQQMCKGTFN
       730        740        750        760        770        780
PFSGDPLPAN PKKQLILKVI SGQQLPKPPD SMFGDRGEII DPFVEVEIIG LPVDCCKDQT
       790        800        810        820        830        840
RVVDDNGFNP VWEETLTFTV HMPEIALVRF LVWDHDPIGR DFVGQRTVTF SSLVPGYRHV
       850        860        870        880        890        900
YLEGLTEASI FVHITINEIF GKWSPLILNP SYTILHFLGA TKNRQLQGLK GLFNKNPRHA
       910        920        930        940        950        960
SSENNSHYVR KRSIGDRILR RTASAPAKGR KKSKVGFQEM VEIKDSVSEA SRDQDGVLRR
       970        980        990       1000       1010       1020
TTRSLQVRPV SMPVDKSLLG ALSLPISEAA KDTDGKENCL AGDKDDRRKG AATRKDPHFS
      1030       1040       1050       1060       1070       1080
NFNKKLSSSS SALLHKDANQ GPTASVSNPE QCGGRGAKSE RIKPNMTNDC QENHNPPKFL
      1090       1100       1110       1120       1130       1140
SPRKHLALDP ATKGLQERLH GMKTNEKEHA EGFLGEKSML SGSVLSQSSL EVENLEGSRA
      1150       1160       1170       1180       1190       1200
KGRAATSFSL SDVSALCSDI PDLHSTAILQ DTEISNLIDD VTLTNENQSG SSISALIGQF
      1210       1220       1230       1240       1250       1260
EESNHPANVT VVSHLSTSGA SGSAPFQTPF KHGLSQGNQK ASFLCSSPEL NKLSSVETTK
      1270       1280       1290       1300       1310       1320
LANNAVPCGV IGSPISTPKP GDDPSDKAKT RVIEGNLPGF PDASPGQFPK SPTHGEDHSQ
      1330       1340       1350       1360       1370       1380
VMNSPALSTE LAIEDIIADP ALSINSAESS LVEIDGESEN LSLTTCDYRE EAPSQLVSPL
      1390       1400       1410       1420       1430       1440
KLQQSQEMVE HIQRGLRNGY CKETLLPSEI FNNIPGVKNH SISHLTYQGA GFVYNHFSSS
      1450       1460       1470       1480       1490       1500
DAKTNQICEP QQPRAPDMHA PTPTPSTHAP LAALKLPSPC KSKSLGDLTS EDIACNFESK
      1510       1520       1530       1540       1550       1560
YQCISRSFVT NGIRDKSVTM KTKSLEPLDA LTEQLRKLVS FDQEDSCQVL YSKQDVNQCP
      1570       1580       1590       1600       1610       1620
RALVRKLSSR SQSRVRNIAS RAKEKQEAGK QKAMAQSTRG GVVLRSKPPA PALAVNRHST
      1630       1640       1650       1660       1670       1680
GSYIASYLRN MKAGGLEGRG IPEGACTALR YGYMDQFCSD NSVLQTEPSS EDKPEIYFLL

RL

Isoforms

- Isoform 2 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 - Isoform 3 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 - Isoform 4 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 - Isoform 5 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

Sequence View

        10         20         30         40         50         60
MADLEVYKNL SPEKVERCMS VMQSGTQMIK LKRGTKGLVR LFYLDEHRTR LRWRPSRKSE
        70         80         90        100        110        120
KAKILIDSIY KVTEGRQSEI FHRQAEGNFD PSCCFTIYHG NHMESLDLIT SNPEEARTWI
       130        140        150        160        170        180
TGLKYLMAGI SDEDSLAKRQ RTHDQWVKQT FEEADKNGDG LLNIEEIHQL MHKLNVNLPR
       190        200        210        220        230        240
RKVRQMFQEA DTDENQGTLT FEEFCVFYKM MSLRRDLYLL LLSYSDKKDH LTVEELAQFL
       250        260        270        280        290        300
KVEQKMSNVT LDYCLDIIMK FEVSEENKVK NVLGIEGFTN FMRSPACDVF NPLHHEVYQD
       310        320        330        340        350        360
MDQPLCNYYI ASSHNTYLTG DQLLSQSKVD MYARVLQEGC RCVEVDCWDG PDGEPVVHHG
       370        380        390        400        410        420
YTLTSKILFR DVVETINKHA FVKNEFPVIL SIENHCSIQQ QRKIAQYLKG ILQDKLDLSS
       430        440        450        460        470        480
VDTGECRQLP SPQSLKGKIL VKGKKLPYHL GDDAEEGEVS DEDSADEIED ECKFKLHYSN
       490        500        510        520        530        540
GTTEHQVESF IRKKLESLLK ESQIRDKEDP DSFTVRALLK ATHEGLNAHL KQNLDVKESG
       550        560        570        580        590        600
KKSHGRSLMA NFGKHKQKAT KSRSKSYSTD DEDDSLQNPG KEGGQLYRLG RRRRTMKLCR
       610        620        630        640        650        660
ELSDLVVYTN SVAAQDIVDD GTTGNVLSFS ETRAHQVVQQ KSEQFMIYNQ KQLTRIYPSA
       670        680        690        700        710        720
YRIDSSNFNP LPYWNAGCQL VALNYQSEGR MMQINRAKFK ANGNCGYILK PQQMCKGTFN
       730        740        750        760        770        780
PFSGDPLPAN PKKQLILKVI SGQQLPKPPD SMFGDRGEII DPFVEVEIIG LPVDCCKDQT
       790        800        810        820        830        840
RVVDDNGFNP VWEETLTFTV HMPEIALVRF LVWDHDPIGR DFVGQRTVTF SSLVPGYRHV
       850        860        870        880        890        900
YLEGLTEASI FVHITINEIF GKWSPLILNP SYTILHFLGA TKNRQLQGLK GLFNKNPRHA
       910        920        930        940        950        960
SSENNSHYVR KRSIGDRILR RTASAPAKGR KKSKVGFQEM VEIKDSVSEA SRDQDGVLRR
       970        980        990       1000       1010       1020
TTRSLQVRPV SMPVDKSLLG ALSLPISEAA KDTDGKENCL AGDKDDRRKG AATRKDPHFS
      1030       1040       1050       1060       1070       1080
NFNKKLSSSS SALLHKDANQ GPTASVSNPE QCGGRGAKSE RIKPNMTNDC QENHNPPKFL
      1090       1100       1110       1120       1130       1140
SPRKHLALDP ATKGLQERLH GMKTNEKEHA EGFLGEKSML SGSVLSQSSL EVENLEGSRA
      1150       1160       1170       1180       1190       1200
KGRAATSFSL SDVSALCSDI PDLHSTAILQ DTEISNLIDD VTLTNENQSG SSISALIGQF
      1210       1220       1230       1240       1250       1260
EESNHPANVT VVSHLSTSGA SGSAPFQTPF KHGLSQGNQK ASFLCSSPEL NKLSSVETTK
      1270       1280       1290       1300       1310       1320
LANNAVPCGV IGSPISTPKP GDDPSDKAKT RVIEGNLPGF PDASPGQFPK SPTHGEDHSQ
      1330       1340       1350       1360       1370       1380
VMNSPALSTE LAIEDIIADP ALSINSAESS LVEIDGESEN LSLTTCDYRE EAPSQLVSPL
      1390       1400       1410       1420       1430       1440
KLQQSQEMVE HIQRGLRNGY CKETLLPSEI FNNIPGVKNH SISHLTYQGA GFVYNHFSSS
      1450       1460       1470       1480       1490       1500
DAKTNQICEP QQPRAPDMHA PTPTPSTHAP LAALKLPSPC KSKSLGDLTS EDIACNFESK
      1510       1520       1530       1540       1550       1560
YQCISRSFVT NGIRDKSVTM KTKSLEPLDA LTEQLRKLVS FDQEDSCQVL YSKQDVNQCP
      1570       1580       1590       1600       1610       1620
RALVRKLSSR SQSRVRNIAS RAKEKQEAGK QKAMAQSTRG GVVLRSKPPA PALAVNRHST
      1630       1640       1650       1660       1670       1680
GSYIASYLRN MKAGGLEGRG IPEGACTALR YGYMDQFCSD NSVLQTEPSS EDKPEIYFLL

RL         10         20         30         40         50         60
MADLEVYKNL SPEKVERCMS VMQSGTQMIK LKRGTKGLVR LFYLDEHRTR LRWRPSRKSE
        70         80         90        100        110        120
KAKILIDSIY KVTEGRQSEI FHRQAEGNFD PSCCFTIYHG NHMESLDLIT SNPEEARTWI
       130        140        150        160        170        180
TGLKYLMAGI SDEDSLAKRQ RTHDQWVKQT FEEADKNGDG LLNIEEIHQL MHKLNVNLPR
       190        200        210        220        230        240
RKVRQMFQEA DTDENQGTLT FEEFCVFYKM MSLRRDLYLL LLSYSDKKDH LTVEELAQFL
       250        260        270        280        290        300
KVEQKMSNVT LDYCLDIIMK FEVSEENKVK NVLGIEGFTN FMRSPACDVF NPLHHEVYQD
       310        320        330        340        350        360
MDQPLCNYYI ASSHNTYLTG DQLLSQSKVD MYARVLQEGC RCVEVDCWDG PDGEPVVHHG
       370        380        390        400        410        420
YTLTSKILFR DVVETINKHA FVKNEFPVIL SIENHCSIQQ QRKIAQYLKG ILQDKLDLSS
       430        440        450        460        470        480
VDTGECRQLP SPQSLKGKIL VKGKKLPYHL GDDAEEGEVS DEDSADEIED ECKFKLHYSN
       490        500        510        520        530        540
GTTEHQVESF IRKKLESLLK ESQIRDKEDP DSFTVRALLK ATHEGLNAHL KQNLDVKESG
       550        560        570        580        590        600
KKSHGRSLMA NFGKHKQKAT KSRSKSYSTD DEDDSLQNPG KEGGQLYRLG RRRRTMKLCR
       610        620        630        640        650        660
ELSDLVVYTN SVAAQDIVDD GTTGNVLSFS ETRAHQVVQQ KSEQFMIYNQ KQLTRIYPSA
       670        680        690        700        710        720
YRIDSSNFNP LPYWNAGCQL VALNYQSEGR MMQINRAKFK ANGNCGYILK PQQMCKGTFN
       730        740        750        760        770        780
PFSGDPLPAN PKKQLILKVI SGQQLPKPPD SMFGDRGEII DPFVEVEIIG LPVDCCKDQT
       790        800        810        820        830        840
RVVDDNGFNP VWEETLTFTV HMPEIALVRF LVWDHDPIGR DFVGQRTVTF SSLVPGYRHV
       850        860        870        880        890        900
YLEGLTEASI FVHITINEIF GKWSPLILNP SYTILHFLGA TKNRQLQGLK GLFNKNPRHA
       910        920        930        940        950        960
SSENNSHYVR KRSIGDRILR RTASAPAKGR KKSKVGFQEM VEIKDSVSEA SRDQDGVLRR
       970        980        990       1000       1010       1020
TTRSLQVRPV SMPVDKSLLG ALSLPISEAA KDTDGKENCL AGDKDDRRKG AATRKDPHFS
      1030       1040       1050       1060       1070       1080
NFNKKLSSSS SALLHKDANQ GPTASVSNPE QCGGRGAKSE RIKPNMTNDC QENHNPPKFL
      1090       1100       1110       1120       1130       1140
SPRKHLALDP ATKGLQERLH GMKTNEKEHA EGFLGEKSML SGSVLSQSSL EVENLEGSRA
      1150       1160       1170       1180       1190       1200
KGRAATSFSL SDVSALCSDI PDLHSTAILQ DTEISNLIDD VTLTNENQSG SSISALIGQF
      1210       1220       1230       1240       1250       1260
EESNHPANVT VVSHLSTSGA SGSAPFQTPF KHGLSQGNQK ASFLCSSPEL NKLSSVETTK
      1270       1280       1290       1300       1310       1320
LANNAVPCGV IGSPISTPKP GDDPSDKAKT RVIEGNLPGF PDASPGQFPK SPTHGEDHSQ
      1330       1340       1350       1360       1370       1380
VMNSPALSTE LAIEDIIADP ALSINSAESS LVEIDGESEN LSLTTCDYRE EAPSQLVSPL
      1390       1400       1410       1420       1430       1440
KLQQSQEMVE HIQRGLRNGY CKETLLPSEI FNNIPGVKNH SISHLTYQGA GFVYNHFSSS
      1450       1460       1470       1480       1490       1500
DAKTNQICEP QQPRAPDMHA PTPTPSTHAP LAALKLPSPC KSKSLGDLTS EDIACNFESK
      1510       1520       1530       1540       1550       1560
YQCISRSFVT NGIRDKSVTM KTKSLEPLDA LTEQLRKLVS FDQEDSCQVL YSKQDVNQCP
      1570       1580       1590       1600       1610       1620
RALVRKLSSR SQSRVRNIAS RAKEKQEAGK QKAMAQSTRG GVVLRSKPPA PALAVNRHST
      1630       1640       1650       1660       1670       1680
GSYIASYLRN MKAGGLEGRG IPEGACTALR YGYMDQFCSD NSVLQTEPSS EDKPEIYFLL

RL         10         20         30         40         50         60
MADLEVYKNL SPEKVERCMS VMQSGTQMIK LKRGTKGLVR LFYLDEHRTR LRWRPSRKSE
        70         80         90        100        110        120
KAKILIDSIY KVTEGRQSEI FHRQAEGNFD PSCCFTIYHG NHMESLDLIT SNPEEARTWI
       130        140        150        160        170        180
TGLKYLMAGI SDEDSLAKRQ RTHDQWVKQT FEEADKNGDG LLNIEEIHQL MHKLNVNLPR
       190        200        210        220        230        240
RKVRQMFQEA DTDENQGTLT FEEFCVFYKM MSLRRDLYLL LLSYSDKKDH LTVEELAQFL
       250        260        270        280        290        300
KVEQKMSNVT LDYCLDIIMK FEVSEENKVK NVLGIEGFTN FMRSPACDVF NPLHHEVYQD
       310        320        330        340        350        360
MDQPLCNYYI ASSHNTYLTG DQLLSQSKVD MYARVLQEGC RCVEVDCWDG PDGEPVVHHG
       370        380        390        400        410        420
YTLTSKILFR DVVETINKHA FVKNEFPVIL SIENHCSIQQ QRKIAQYLKG ILQDKLDLSS
       430        440        450        460        470        480
VDTGECRQLP SPQSLKGKIL VKGKKLPYHL GDDAEEGEVS DEDSADEIED ECKFKLHYSN
       490        500        510        520        530        540
GTTEHQVESF IRKKLESLLK ESQIRDKEDP DSFTVRALLK ATHEGLNAHL KQNLDVKESG
       550        560        570        580        590        600
KKSHGRSLMA NFGKHKQKAT KSRSKSYSTD DEDDSLQNPG KEGGQLYRLG RRRRTMKLCR
       610        620        630        640        650        660
ELSDLVVYTN SVAAQDIVDD GTTGNVLSFS ETRAHQVVQQ KSEQFMIYNQ KQLTRIYPSA
       670        680        690        700        710        720
YRIDSSNFNP LPYWNAGCQL VALNYQSEGR MMQINRAKFK ANGNCGYILK PQQMCKGTFN
       730        740        750        760        770        780
PFSGDPLPAN PKKQLILKVI SGQQLPKPPD SMFGDRGEII DPFVEVEIIG LPVDCCKDQT
       790        800        810        820        830        840
RVVDDNGFNP VWEETLTFTV HMPEIALVRF LVWDHDPIGR DFVGQRTVTF SSLVPGYRHV
       850        860        870        880        890        900
YLEGLTEASI FVHITINEIF GKWSPLILNP SYTILHFLGA TKNRQLQGLK GLFNKNPRHA
       910        920        930        940        950        960
SSENNSHYVR KRSIGDRILR RTASAPAKGR KKSKVGFQEM VEIKDSVSEA SRDQDGVLRR
       970        980        990       1000       1010       1020
TTRSLQVRPV SMPVDKSLLG ALSLPISEAA KDTDGKENCL AGDKDDRRKG AATRKDPHFS
      1030       1040       1050       1060       1070       1080
NFNKKLSSSS SALLHKDANQ GPTASVSNPE QCGGRGAKSE RIKPNMTNDC QENHNPPKFL
      1090       1100       1110       1120       1130       1140
SPRKHLALDP ATKGLQERLH GMKTNEKEHA EGFLGEKSML SGSVLSQSSL EVENLEGSRA
      1150       1160       1170       1180       1190       1200
KGRAATSFSL SDVSALCSDI PDLHSTAILQ DTEISNLIDD VTLTNENQSG SSISALIGQF
      1210       1220       1230       1240       1250       1260
EESNHPANVT VVSHLSTSGA SGSAPFQTPF KHGLSQGNQK ASFLCSSPEL NKLSSVETTK
      1270       1280       1290       1300       1310       1320
LANNAVPCGV IGSPISTPKP GDDPSDKAKT RVIEGNLPGF PDASPGQFPK SPTHGEDHSQ
      1330       1340       1350       1360       1370       1380
VMNSPALSTE LAIEDIIADP ALSINSAESS LVEIDGESEN LSLTTCDYRE EAPSQLVSPL
      1390       1400       1410       1420       1430       1440
KLQQSQEMVE HIQRGLRNGY CKETLLPSEI FNNIPGVKNH SISHLTYQGA GFVYNHFSSS
      1450       1460       1470       1480       1490       1500
DAKTNQICEP QQPRAPDMHA PTPTPSTHAP LAALKLPSPC KSKSLGDLTS EDIACNFESK
      1510       1520       1530       1540       1550       1560
YQCISRSFVT NGIRDKSVTM KTKSLEPLDA LTEQLRKLVS FDQEDSCQVL YSKQDVNQCP
      1570       1580       1590       1600       1610       1620
RALVRKLSSR SQSRVRNIAS RAKEKQEAGK QKAMAQSTRG GVVLRSKPPA PALAVNRHST
      1630       1640       1650       1660       1670       1680
GSYIASYLRN MKAGGLEGRG IPEGACTALR YGYMDQFCSD NSVLQTEPSS EDKPEIYFLL

RL         10         20         30         40         50         60
MADLEVYKNL SPEKVERCMS VMQSGTQMIK LKRGTKGLVR LFYLDEHRTR LRWRPSRKSE
        70         80         90        100        110        120
KAKILIDSIY KVTEGRQSEI FHRQAEGNFD PSCCFTIYHG NHMESLDLIT SNPEEARTWI
       130        140        150        160        170        180
TGLKYLMAGI SDEDSLAKRQ RTHDQWVKQT FEEADKNGDG LLNIEEIHQL MHKLNVNLPR
       190        200        210        220        230        240
RKVRQMFQEA DTDENQGTLT FEEFCVFYKM MSLRRDLYLL LLSYSDKKDH LTVEELAQFL
       250        260        270        280        290        300
KVEQKMSNVT LDYCLDIIMK FEVSEENKVK NVLGIEGFTN FMRSPACDVF NPLHHEVYQD
       310        320        330        340        350        360
MDQPLCNYYI ASSHNTYLTG DQLLSQSKVD MYARVLQEGC RCVEVDCWDG PDGEPVVHHG
       370        380        390        400        410        420
YTLTSKILFR DVVETINKHA FVKNEFPVIL SIENHCSIQQ QRKIAQYLKG ILQDKLDLSS
       430        440        450        460        470        480
VDTGECRQLP SPQSLKGKIL VKGKKLPYHL GDDAEEGEVS DEDSADEIED ECKFKLHYSN
       490        500        510        520        530        540
GTTEHQVESF IRKKLESLLK ESQIRDKEDP DSFTVRALLK ATHEGLNAHL KQNLDVKESG
       550        560        570        580        590        600
KKSHGRSLMA NFGKHKQKAT KSRSKSYSTD DEDDSLQNPG KEGGQLYRLG RRRRTMKLCR
       610        620        630        640        650        660
ELSDLVVYTN SVAAQDIVDD GTTGNVLSFS ETRAHQVVQQ KSEQFMIYNQ KQLTRIYPSA
       670        680        690        700        710        720
YRIDSSNFNP LPYWNAGCQL VALNYQSEGR MMQINRAKFK ANGNCGYILK PQQMCKGTFN
       730        740        750        760        770        780
PFSGDPLPAN PKKQLILKVI SGQQLPKPPD SMFGDRGEII DPFVEVEIIG LPVDCCKDQT
       790        800        810        820        830        840
RVVDDNGFNP VWEETLTFTV HMPEIALVRF LVWDHDPIGR DFVGQRTVTF SSLVPGYRHV
       850        860        870        880        890        900
YLEGLTEASI FVHITINEIF GKWSPLILNP SYTILHFLGA TKNRQLQGLK GLFNKNPRHA
       910        920        930        940        950        960
SSENNSHYVR KRSIGDRILR RTASAPAKGR KKSKVGFQEM VEIKDSVSEA SRDQDGVLRR
       970        980        990       1000       1010       1020
TTRSLQVRPV SMPVDKSLLG ALSLPISEAA KDTDGKENCL AGDKDDRRKG AATRKDPHFS
      1030       1040       1050       1060       1070       1080
NFNKKLSSSS SALLHKDANQ GPTASVSNPE QCGGRGAKSE RIKPNMTNDC QENHNPPKFL
      1090       1100       1110       1120       1130       1140
SPRKHLALDP ATKGLQERLH GMKTNEKEHA EGFLGEKSML SGSVLSQSSL EVENLEGSRA
      1150       1160       1170       1180       1190       1200
KGRAATSFSL SDVSALCSDI PDLHSTAILQ DTEISNLIDD VTLTNENQSG SSISALIGQF
      1210       1220       1230       1240       1250       1260
EESNHPANVT VVSHLSTSGA SGSAPFQTPF KHGLSQGNQK ASFLCSSPEL NKLSSVETTK
      1270       1280       1290       1300       1310       1320
LANNAVPCGV IGSPISTPKP GDDPSDKAKT RVIEGNLPGF PDASPGQFPK SPTHGEDHSQ
      1330       1340       1350       1360       1370       1380
VMNSPALSTE LAIEDIIADP ALSINSAESS LVEIDGESEN LSLTTCDYRE EAPSQLVSPL
      1390       1400       1410       1420       1430       1440
KLQQSQEMVE HIQRGLRNGY CKETLLPSEI FNNIPGVKNH SISHLTYQGA GFVYNHFSSS
      1450       1460       1470       1480       1490       1500
DAKTNQICEP QQPRAPDMHA PTPTPSTHAP LAALKLPSPC KSKSLGDLTS EDIACNFESK
      1510       1520       1530       1540       1550       1560
YQCISRSFVT NGIRDKSVTM KTKSLEPLDA LTEQLRKLVS FDQEDSCQVL YSKQDVNQCP
      1570       1580       1590       1600       1610       1620
RALVRKLSSR SQSRVRNIAS RAKEKQEAGK QKAMAQSTRG GVVLRSKPPA PALAVNRHST
      1630       1640       1650       1660       1670       1680
GSYIASYLRN MKAGGLEGRG IPEGACTALR YGYMDQFCSD NSVLQTEPSS EDKPEIYFLL

RL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q4KWH5-1-unknown	MADLEV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q4KWH5-1-unknown	MADLEV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85502
Q4KWH5-1-unknown	MADLEV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85503
Q4KWH5-22-unknown	MQSGTQ...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85501
Q4KWH5-22-unknown	MQSGTQ...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109907
Q4KWH5-22-unknown	MQSGTQ...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109908

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...FLLRL	1682	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...FLLRL	1682	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt81119

TopFIND

Q4KWH5: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

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Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

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Substrates