TopFIND 4.0

Q4QRL3: Coiled-coil domain-containing protein 88B

General Information

Protein names
- Coiled-coil domain-containing protein 88B
- Gipie {ECO:0000303|PubMed:21289099}
- Hook-related protein 3
- HkRP3
Gene names Ccdc88b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q4QRL3

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEGAKGPRLR GFLSGSLATW ALGLAGLVGE AEESAGGTEE EEEEEEEEGA LCTEKRFLRL 
        70         80         90        100        110        120 
IDGALLLRVL GIIAPSSRGG LRMVRGRDGP AACRMWNLCH LWGRLRDFYQ EELQLLILSP 
       130        140        150        160        170        180 
PPDLQTMGCD PFSEEAVDEL ESILRLLLGA SVQCEHRELF IRHIRGLSLD VQSELAGAIQ 
       190        200        210        220        230        240 
EVTQPGAGVV LALAGPESGE LVAEELEMQL RSLTGMMSRL ARERDLGAQR LAELLLEREP 
       250        260        270        280        290        300 
AHLLLPEAPA NASAEGVSHH LALQLTNAKA QLRRLRQEVE EKAEQLLDSQ AEVQGLEAEI 
       310        320        330        340        350        360 
RRLRQETQAL SAQAKRAELY REEAEALRER AGRLPRLQEE LRRCREKLQA AEVFKGQLEE 
       370        380        390        400        410        420 
ERVLSEALEA SKVLLEEQLE VARERSARLH ETQRENLLLR TRLGEAHADL DSLRHQLEQL 
       430        440        450        460        470        480 
VEENVELELE LQRSLEPPPG SPGEASLPGA APSLQDEVRE AEAGRLRAVE RENRELRGQL 
       490        500        510        520        530        540 
QMLQAQLGSQ HPLLEEQREN SRQPPVPNRD PATPSALHHS PQSPACQIGG EGSESLDLPS 
       550        560        570        580        590        600 
PASYSDITRS PKCSQAPDSH PELESPLQMV SQDPQTSDQA LQESDPTVET HQCLEKSGHR 
       610        620        630        640        650        660 
VPLQSPIVWD PPQGPEVRIE VQELLGETGS REAPQGELVH KAQVLKQESP KCRPRSAELT 
       670        680        690        700        710        720 
LREPLKDQKA LDRELELSKQ QKETGRHEQR PKGLESKLGP QKPQQTSEGV PDAWSREEPT 
       730        740        750        760        770        780 
PGETLVSAIP EEQALRDEVA QLRREVAGLE VKLQAQAQRL EARSAEALCL SEELAQARRT 
       790        800        810        820        830        840 
EAEAHQEAEA QAREQARLRE AVDTASLELE AASREREALA EALAAAGRER RQWERDGPRL 
       850        860        870        880        890        900 
RAQVEAAEQQ VQALESQVRC HLEEAEREHA EKQALREELE KAVLRGQELG DRLEHLQEEL 
       910        920        930        940        950        960 
EQAALERQKF LQEQENQHQR YRHLEQRLEA ELQAASTSKE EALMELKARA LQLEEELIQL 
       970        980        990       1000       1010       1020 
RQYPVDLATG ARAGPRTVET QNGRLIEVER NNATLVAEKA ALQGQLQHLE GQLGSLQGRA 
      1030       1040       1050       1060       1070       1080 
QELLLQSQRA QEHSSRLQAE KSMMEMQGQE LHRKLGVLEE EVRAARRAQE ETRGQQQALL 
      1090       1100       1110       1120       1130       1140 
RDHEALVQLQ RRQETELEGL LVRHRDLKAN MRALELAHRE LQGRHEQLQA QRANVEAQEV 
      1150       1160       1170       1180       1190       1200 
ALLAERERLM QDGHRQRGLE EELRRLQNEH ERAQMLLAEV SRERGELQGE RGELRSRLAR 
      1210       1220       1230       1240       1250       1260 
LELERAQLEI QSQQLRESNQ QLDLSACRLT TQCELLTQLR SAQEEENRQL LAEVQALSRE 
      1270       1280       1290       1300       1310       1320 
NRELLERSLE SRDHLHREQR EYLDQLNALR REKQKLVEKI MDQYRVLEPG PLPRTKKGSW 
      1330       1340       1350       1360       1370       1380 
LADKVKRLIR PRREGALHGG PRLGADGAGS TESLGGPLET ELPEGREADG TGSSSPAPMR 
      1390       1400       1410       1420       1430       1440 
RVQSSLCLGD ETLAGGQRRR LSSRFPGGRS SASFSPGDTP RQRFRQRRPG PLGAPSTHSK 
      1450       1460       1470       1480    
GSGVEWDGSI KTLSEHEADD TREAFQEQKP EKQFLTPSLS Q

Isoforms

- Isoform 2 of Coiled-coil domain-containing protein 88B

Sequence View

        10         20         30         40         50         60 
MEGAKGPRLR GFLSGSLATW ALGLAGLVGE AEESAGGTEE EEEEEEEEGA LCTEKRFLRL 
        70         80         90        100        110        120 
IDGALLLRVL GIIAPSSRGG LRMVRGRDGP AACRMWNLCH LWGRLRDFYQ EELQLLILSP 
       130        140        150        160        170        180 
PPDLQTMGCD PFSEEAVDEL ESILRLLLGA SVQCEHRELF IRHIRGLSLD VQSELAGAIQ 
       190        200        210        220        230        240 
EVTQPGAGVV LALAGPESGE LVAEELEMQL RSLTGMMSRL ARERDLGAQR LAELLLEREP 
       250        260        270        280        290        300 
AHLLLPEAPA NASAEGVSHH LALQLTNAKA QLRRLRQEVE EKAEQLLDSQ AEVQGLEAEI 
       310        320        330        340        350        360 
RRLRQETQAL SAQAKRAELY REEAEALRER AGRLPRLQEE LRRCREKLQA AEVFKGQLEE 
       370        380        390        400        410        420 
ERVLSEALEA SKVLLEEQLE VARERSARLH ETQRENLLLR TRLGEAHADL DSLRHQLEQL 
       430        440        450        460        470        480 
VEENVELELE LQRSLEPPPG SPGEASLPGA APSLQDEVRE AEAGRLRAVE RENRELRGQL 
       490        500        510        520        530        540 
QMLQAQLGSQ HPLLEEQREN SRQPPVPNRD PATPSALHHS PQSPACQIGG EGSESLDLPS 
       550        560        570        580        590        600 
PASYSDITRS PKCSQAPDSH PELESPLQMV SQDPQTSDQA LQESDPTVET HQCLEKSGHR 
       610        620        630        640        650        660 
VPLQSPIVWD PPQGPEVRIE VQELLGETGS REAPQGELVH KAQVLKQESP KCRPRSAELT 
       670        680        690        700        710        720 
LREPLKDQKA LDRELELSKQ QKETGRHEQR PKGLESKLGP QKPQQTSEGV PDAWSREEPT 
       730        740        750        760        770        780 
PGETLVSAIP EEQALRDEVA QLRREVAGLE VKLQAQAQRL EARSAEALCL SEELAQARRT 
       790        800        810        820        830        840 
EAEAHQEAEA QAREQARLRE AVDTASLELE AASREREALA EALAAAGRER RQWERDGPRL 
       850        860        870        880        890        900 
RAQVEAAEQQ VQALESQVRC HLEEAEREHA EKQALREELE KAVLRGQELG DRLEHLQEEL 
       910        920        930        940        950        960 
EQAALERQKF LQEQENQHQR YRHLEQRLEA ELQAASTSKE EALMELKARA LQLEEELIQL 
       970        980        990       1000       1010       1020 
RQYPVDLATG ARAGPRTVET QNGRLIEVER NNATLVAEKA ALQGQLQHLE GQLGSLQGRA 
      1030       1040       1050       1060       1070       1080 
QELLLQSQRA QEHSSRLQAE KSMMEMQGQE LHRKLGVLEE EVRAARRAQE ETRGQQQALL 
      1090       1100       1110       1120       1130       1140 
RDHEALVQLQ RRQETELEGL LVRHRDLKAN MRALELAHRE LQGRHEQLQA QRANVEAQEV 
      1150       1160       1170       1180       1190       1200 
ALLAERERLM QDGHRQRGLE EELRRLQNEH ERAQMLLAEV SRERGELQGE RGELRSRLAR 
      1210       1220       1230       1240       1250       1260 
LELERAQLEI QSQQLRESNQ QLDLSACRLT TQCELLTQLR SAQEEENRQL LAEVQALSRE 
      1270       1280       1290       1300       1310       1320 
NRELLERSLE SRDHLHREQR EYLDQLNALR REKQKLVEKI MDQYRVLEPG PLPRTKKGSW 
      1330       1340       1350       1360       1370       1380 
LADKVKRLIR PRREGALHGG PRLGADGAGS TESLGGPLET ELPEGREADG TGSSSPAPMR 
      1390       1400       1410       1420       1430       1440 
RVQSSLCLGD ETLAGGQRRR LSSRFPGGRS SASFSPGDTP RQRFRQRRPG PLGAPSTHSK 
      1450       1460       1470       1480    
GSGVEWDGSI KTLSEHEADD TREAFQEQKP EKQFLTPSLS Q



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q4QRL3-1-unknown MEGAKG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q4QRL3-1-unknown MEGAKG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69634

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PSLSQ 1481 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PSLSQ 1481 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65252

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)