Q53GD3: Choline transporter-like protein 4 {ECO:0000303|PubMed:23651124}

General Information

Protein names	- Choline transporter-like protein 4 {ECO:0000303\|PubMed:23651124} - Solute carrier family 44 member 4 {ECO:0000312\|HGNC:HGNC:13941} - Thiamine pyrophosphate transporter 1 {ECO:0000303\|PubMed:24379411} - hTPPT1 {ECO:0000303\|PubMed:24379411}
Gene names	SLC44A4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q53GD3

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Choline transporter-like protein 4 - Isoform 3 of Choline transporter-like protein 4 - Isoform 4 of Choline transporter-like protein 4

Sequence View

        10         20         30         40         50         60
MGGKQRDEDD EAYGKPVKYD PSFRGPIKNR SCTDVICCVL FLLFILGYIV VGIVAWLYGD
        70         80         90        100        110        120
PRQVLYPRNS TGAYCGMGEN KDKPYLLYFN IFSCILSSNI ISVAENGLQC PTPQVCVSSC
       130        140        150        160        170        180
PEDPWTVGKN EFSQTVGEVF YTKNRNFCLP GVPWNMTVIT SLQQELCPSF LLPSAPALGR
       190        200        210        220        230        240
CFPWTNVTPP ALPGITNDTT IQQGISGLID SLNARDISVK IFEDFAQSWY WILVALGVAL
       250        260        270        280        290        300
VLSLLFILLL RLVAGPLVLV LILGVLGVLA YGIYYCWEEY RVLRDKGASI SQLGFTTNLS
       310        320        330        340        350        360
AYQSVQETWL AALIVLAVLE AILLLMLIFL RQRIRIAIAL LKEASKAVGQ MMSTMFYPLV
       370        380        390        400        410        420
TFVLLLICIA YWAMTALYLA TSGQPQYVLW ASNISSPGCE KVPINTSCNP TAHLVNSSCP
       430        440        450        460        470        480
GLMCVFQGYS SKGLIQRSVF NLQIYGVLGL FWTLNWVLAL GQCVLAGAFA SFYWAFHKPQ
       490        500        510        520        530        540
DIPTFPLISA FIRTLRYHTG SLAFGALILT LVQIARVILE YIDHKLRGVQ NPVARCIMCC
       550        560        570        580        590        600
FKCCLWCLEK FIKFLNRNAY IMIAIYGKNF CVSAKNAFML LMRNIVRVVV LDKVTDLLLF
       610        620        630        640        650        660
FGKLLVVGGV GVLSFFFFSG RIPGLGKDFK SPHLNYYWLP IMTSILGAYV IASGFFSVFG
       670        680        690        700        710
MCVDTLFLCF LEDLERNNGS LDRPYYMSKS LLKILGKKNE APPDNKKRKK         10         20         30         40         50         60
MGGKQRDEDD EAYGKPVKYD PSFRGPIKNR SCTDVICCVL FLLFILGYIV VGIVAWLYGD
        70         80         90        100        110        120
PRQVLYPRNS TGAYCGMGEN KDKPYLLYFN IFSCILSSNI ISVAENGLQC PTPQVCVSSC
       130        140        150        160        170        180
PEDPWTVGKN EFSQTVGEVF YTKNRNFCLP GVPWNMTVIT SLQQELCPSF LLPSAPALGR
       190        200        210        220        230        240
CFPWTNVTPP ALPGITNDTT IQQGISGLID SLNARDISVK IFEDFAQSWY WILVALGVAL
       250        260        270        280        290        300
VLSLLFILLL RLVAGPLVLV LILGVLGVLA YGIYYCWEEY RVLRDKGASI SQLGFTTNLS
       310        320        330        340        350        360
AYQSVQETWL AALIVLAVLE AILLLMLIFL RQRIRIAIAL LKEASKAVGQ MMSTMFYPLV
       370        380        390        400        410        420
TFVLLLICIA YWAMTALYLA TSGQPQYVLW ASNISSPGCE KVPINTSCNP TAHLVNSSCP
       430        440        450        460        470        480
GLMCVFQGYS SKGLIQRSVF NLQIYGVLGL FWTLNWVLAL GQCVLAGAFA SFYWAFHKPQ
       490        500        510        520        530        540
DIPTFPLISA FIRTLRYHTG SLAFGALILT LVQIARVILE YIDHKLRGVQ NPVARCIMCC
       550        560        570        580        590        600
FKCCLWCLEK FIKFLNRNAY IMIAIYGKNF CVSAKNAFML LMRNIVRVVV LDKVTDLLLF
       610        620        630        640        650        660
FGKLLVVGGV GVLSFFFFSG RIPGLGKDFK SPHLNYYWLP IMTSILGAYV IASGFFSVFG
       670        680        690        700        710
MCVDTLFLCF LEDLERNNGS LDRPYYMSKS LLKILGKKNE APPDNKKRKK         10         20         30         40         50         60
MGGKQRDEDD EAYGKPVKYD PSFRGPIKNR SCTDVICCVL FLLFILGYIV VGIVAWLYGD
        70         80         90        100        110        120
PRQVLYPRNS TGAYCGMGEN KDKPYLLYFN IFSCILSSNI ISVAENGLQC PTPQVCVSSC
       130        140        150        160        170        180
PEDPWTVGKN EFSQTVGEVF YTKNRNFCLP GVPWNMTVIT SLQQELCPSF LLPSAPALGR
       190        200        210        220        230        240
CFPWTNVTPP ALPGITNDTT IQQGISGLID SLNARDISVK IFEDFAQSWY WILVALGVAL
       250        260        270        280        290        300
VLSLLFILLL RLVAGPLVLV LILGVLGVLA YGIYYCWEEY RVLRDKGASI SQLGFTTNLS
       310        320        330        340        350        360
AYQSVQETWL AALIVLAVLE AILLLMLIFL RQRIRIAIAL LKEASKAVGQ MMSTMFYPLV
       370        380        390        400        410        420
TFVLLLICIA YWAMTALYLA TSGQPQYVLW ASNISSPGCE KVPINTSCNP TAHLVNSSCP
       430        440        450        460        470        480
GLMCVFQGYS SKGLIQRSVF NLQIYGVLGL FWTLNWVLAL GQCVLAGAFA SFYWAFHKPQ
       490        500        510        520        530        540
DIPTFPLISA FIRTLRYHTG SLAFGALILT LVQIARVILE YIDHKLRGVQ NPVARCIMCC
       550        560        570        580        590        600
FKCCLWCLEK FIKFLNRNAY IMIAIYGKNF CVSAKNAFML LMRNIVRVVV LDKVTDLLLF
       610        620        630        640        650        660
FGKLLVVGGV GVLSFFFFSG RIPGLGKDFK SPHLNYYWLP IMTSILGAYV IASGFFSVFG
       670        680        690        700        710
MCVDTLFLCF LEDLERNNGS LDRPYYMSKS LLKILGKKNE APPDNKKRKK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q53GD3-1-unknown	MGGKQR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q53GD3-1-unknown	MGGKQR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72032
Q53GD3-77-unknown	MGENKD...	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72031
Q53GD3-77-unknown	MGENKD...	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000446935
Q53GD3-77-unknown	MGENKD...	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000450005
Q53GD3-77-unknown	MGENKD...	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000448213
Q53GD3-77-unknown	MGENKD...	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101275
Q53GD3-423-unknown	MCVFQG...	423	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72030
Q53GD3-423-unknown	MCVFQG...	423	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101221
Q53GD3-423-unknown	MCVFQG...	423	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101220

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DHKLRG	527	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000414296
...DHKLRG	527	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415708
...DHKLRG	527	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400263
...KKRKK	710	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KKRKK	710	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67648
...KKRKK	710	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67649
...KKRKK	710	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67650

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)