Q53GL7: Protein mono-ADP-ribosyltransferase PARP10 {ECO:0000305}

General Information

Protein names	- Protein mono-ADP-ribosyltransferase PARP10 {ECO:0000305} - 2.4.2.- {ECO:0000269\|PubMed:18851833, ECO:0000269\|PubMed:25043379} - ADP-ribosyltransferase diphtheria toxin-like 10 {ECO:0000303\|PubMed:20106667} - ARTD10 {ECO:0000303\|PubMed:20106667} - Poly ADP-ribose] polymerase 10 {ECO:0000303\|PubMed:20106667} - PARP-10 {ECO:0000303\|PubMed:20106667}
Gene names	PARP10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q53GL7

1 N-termini

11 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVAMAEAEAG VAVEVRGLPP AVPDELLTLY FENRRRSGGG PVLSWQRLGC GGVLTFREPA
        70         80         90        100        110        120
DAERVLAQAD HELHGAQLSL RPAPPRAPAR LLLQGLPPGT TPQRLEQHVQ ALLRASGLPV
       130        140        150        160        170        180
QPCCALASPR PDRALVQLPK PLSEADVRVL EEQAQNLGLE GTLVSLARVP QARAVRVVGD
       190        200        210        220        230        240
GASVDLLLLE LYLENERRSG GGPLEDLQRL PGPLGTVASF QQWQVAERVL QQEHRLQGSE
       250        260        270        280        290        300
LSLVPHYDIL EPEELAENTS GGDHPSTQGP RATKHALLRT GGLVTALQGA GTVTMGSGEE
       310        320        330        340        350        360
PGQSGASLRT GPMVQGRGIM TTGSGQEPGQ SGTSLRTGPM GSLGQAEQVS SMPMGSLEHE
       370        380        390        400        410        420
GLVSLRPVGL QEQEGPMSLG PVGSAGPVET SKGLLGQEGL VEIAMDSPEQ EGLVGPMEIT
       430        440        450        460        470        480
MGSLEKAGPV SPGCVKLAGQ EGLVEMVLLM EPGAMRFLQL YHEDLLAGLG DVALLPLEGP
       490        500        510        520        530        540
DMTGFRLCGA QASCQAAEEF LRSLLGSISC HVLCLEHPGS ARFLLGPEGQ HLLQGLEAQF
       550        560        570        580        590        600
QCVFGTERLA TATLDTGLEE VDPTEALPVL PGNAHTLWTP DSTGGDQEDV SLEEVRELLA
       610        620        630        640        650        660
TLEGLDLDGE DWLPRELEEE GPQEQPEEEV TPGHEEEEPV APSTVAPRWL EEEAALQLAL
       670        680        690        700        710        720
HRSLEPQGQV AEQEEAAALR QALTLSLLEQ PPLEAEEPPD GGTDGKAQLV VHSAFEQDVE
       730        740        750        760        770        780
ELDRALRAAL EVHVQEETVG PWRRTLPAEL RARLERCHGV SVALRGDCTI LRGFGAHPAR
       790        800        810        820        830        840
AARHLVALLA GPWDQSLAFP LAASGPTLAG QTLKGPWNNL ERLAENTGEF QEVVRAFYDT
       850        860        870        880        890        900
LDAARSSIRV VRVERVSHPL LQQQYELYRE RLLQRCERRP VEQVLYHGTT APAVPDICAH
       910        920        930        940        950        960
GFNRSFCGRN ATVYGKGVYF ARRASLSVQD RYSPPNADGH KAVFVARVLT GDYGQGRRGL
       970        980        990       1000       1010       1020
RAPPLRGPGH VLLRYDSAVD CICQPSIFVI FHDTQALPTH LITCEHVPRA SPDDPSGLPG

RSPDT

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

1 N-termini - 11 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q53GL7-1-unknown	MVAMAE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QLSLRP	81	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433990
...QLSLRP	81	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456874
...SLRPAP	83	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435161
...SLRPAP	83	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457412
...PPRAPA	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436333
...PPRAPA	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456504
...PQRLEQ	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434411
...PQRLEQ	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457124
...CALASP	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431250
...CALASP	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456577
...PDRALV	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434005
...PDRALV	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457138
...KPLSEA	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000432204
...KPLSEA	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436697
...KPLSEA	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455889
...KPLSEA	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455433
...RVPQAR	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431818
...RVPQAR	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456411
...AVRVVG	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436301
...AVRVVG	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456014
...TMGSLE	424	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000314320
...TMGSLE	424	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457710
...RSPDT	1025	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)