TopFIND 4.0

Q53H47: Histone-lysine N-methyltransferase SETMAR {ECO:0000305}

General Information

Protein names
- Histone-lysine N-methyltransferase SETMAR {ECO:0000305}
- SET domain and mariner transposase fusion protein {ECO:0000305}
- Metnase {ECO:0000303|PubMed:16332963}
- Histone-lysine N-methyltransferase {ECO:0000305}
- 2.1.1.43 {ECO:0000269|PubMed:16332963}
- Transposon Hsmar1 transposase {ECO:0000303|PubMed:9461395}
- 3.1.-.- {ECO:0000269|PubMed:16332963}
Gene names SETMAR
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q53H47

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 
        70         80         90        100        110        120 
PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 
       130        140        150        160        170        180 
LCRCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIP KGRFVCEYAG EVLGFSEVQR 
       190        200        210        220        230        240 
RIHLQTKSDS NYIIAIREHV YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM 
       250        260        270        280        290        300 
VPKLALFAAK DIVPEEELSY DYSGRYLNLT VSEDKERLDH GKLRKPCYCG AKSCTAFLPF 
       310        320        330        340        350        360 
DSSLYCPVEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ IRAIFLFEFK 
       370        380        390        400        410        420 
MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL EDEERSGRPS EVDNDQLRAI 
       430        440        450        460        470        480 
IEADPLTTTR EVAEELNVNH STVVRHLKQI GKVKKLDKWV PHELTENQKN RRFEVSSSLI 
       490        500        510        520        530        540 
LRNHNEPFLD RIVTCDEKWI LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA 
       550        560        570        580        590        600 
GLIHYSFLNP GETITSEKYA QEIDEMNQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 
       610        620        630        640        650        660 
KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ EFVESQSTDF 
       670        680    
YATGINQLIS RWQKCVDCNG SYFD

Isoforms

- Isoform 2 of Histone-lysine N-methyltransferase SETMAR - Isoform 3 of Histone-lysine N-methyltransferase SETMAR

Sequence View

        10         20         30         40         50         60 
MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 
        70         80         90        100        110        120 
PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 
       130        140        150        160        170        180 
LCRCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIP KGRFVCEYAG EVLGFSEVQR 
       190        200        210        220        230        240 
RIHLQTKSDS NYIIAIREHV YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM 
       250        260        270        280        290        300 
VPKLALFAAK DIVPEEELSY DYSGRYLNLT VSEDKERLDH GKLRKPCYCG AKSCTAFLPF 
       310        320        330        340        350        360 
DSSLYCPVEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ IRAIFLFEFK 
       370        380        390        400        410        420 
MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL EDEERSGRPS EVDNDQLRAI 
       430        440        450        460        470        480 
IEADPLTTTR EVAEELNVNH STVVRHLKQI GKVKKLDKWV PHELTENQKN RRFEVSSSLI 
       490        500        510        520        530        540 
LRNHNEPFLD RIVTCDEKWI LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA 
       550        560        570        580        590        600 
GLIHYSFLNP GETITSEKYA QEIDEMNQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 
       610        620        630        640        650        660 
KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ EFVESQSTDF 
       670        680    
YATGINQLIS RWQKCVDCNG SYFD         10         20         30         40         50         60 
MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 
        70         80         90        100        110        120 
PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 
       130        140        150        160        170        180 
LCRCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIP KGRFVCEYAG EVLGFSEVQR 
       190        200        210        220        230        240 
RIHLQTKSDS NYIIAIREHV YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM 
       250        260        270        280        290        300 
VPKLALFAAK DIVPEEELSY DYSGRYLNLT VSEDKERLDH GKLRKPCYCG AKSCTAFLPF 
       310        320        330        340        350        360 
DSSLYCPVEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ IRAIFLFEFK 
       370        380        390        400        410        420 
MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL EDEERSGRPS EVDNDQLRAI 
       430        440        450        460        470        480 
IEADPLTTTR EVAEELNVNH STVVRHLKQI GKVKKLDKWV PHELTENQKN RRFEVSSSLI 
       490        500        510        520        530        540 
LRNHNEPFLD RIVTCDEKWI LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA 
       550        560        570        580        590        600 
GLIHYSFLNP GETITSEKYA QEIDEMNQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 
       610        620        630        640        650        660 
KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ EFVESQSTDF 
       670        680    
YATGINQLIS RWQKCVDCNG SYFD



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q53H47-1-unknown MFAEAA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q53H47-1-unknown MFAEAA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89365
    Q53H47-1-unknown MFAEAA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89366

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)