TopFIND 4.0

Q53T94: TATA box-binding protein-associated factor RNA polymerase I subunit B

General Information

Protein names
- TATA box-binding protein-associated factor RNA polymerase I subunit B
- RNA polymerase I-specific TBP-associated factor 63 kDa
- TAFI63
- TATA box-binding protein-associated factor 1B
- TBP-associated factor 1B
- Transcription initiation factor SL1/TIF-IB subunit B
Gene names TAF1B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q53T94

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLEEAEEFK ERCTQCAAVS WGLTDEGKYY CTSCHNVTER YQEVTNTDLI PNTQIKALNR 
        70         80         90        100        110        120 
GLKKKNNTEK GWDWYVCEGF QYILYQQAEA LKNLGVGPEL KNDVLHNFWK RYLQKSKQAY 
       130        140        150        160        170        180 
CKNPVYTTGR KPTVLEDNLS HSDWASEPEL LSDVSCPPFL ESGAESQSDI HTRKPFPVSK 
       190        200        210        220        230        240 
ASQSETSVCS GSLDGVEYSQ RKEKGIVKMT MPQTLAFCYL SLLWQREAIT LSDLLRFVEE 
       250        260        270        280        290        300 
DHIPYINAFQ HFPEQMKLYG RDRGIFGIES WPDYEDIYKK TVEVGTFLDL PRFPDITEDC 
       310        320        330        340        350        360 
YLHPNILCMK YLMEVNLPDE MHSLTCHVVK MTGMGEVDFL TFDPIAKMAK TVKYDVQAVA 
       370        380        390        400        410        420 
IIVVVLKLLF LLDDSFEWSL SNLAEKHNEK NKKDKPWFDF RKWYQIMKKA FDEKKQKWEE 
       430        440        450        460        470        480 
ARAKYLWKSE KPLYYSFVDK PVAYKKREMV VNLQKQFSTL VESTATAGKK SPSSFQFNWT 
       490        500        510        520        530        540 
EEDTDRTCFH GHSLQGVLKE KGQSLLTKNS LYWLSTQKFC RCYCTHVTTY EESNYSLSYQ 
       550        560        570        580    
FILNLFSFLL RIKTSLLHEE VSLVEKKLFE KKYSVKRKKS RSKKVRRH

Isoforms

- Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit B - Isoform 3 of TATA box-binding protein-associated factor RNA polymerase I subunit B

Sequence View

        10         20         30         40         50         60 
MDLEEAEEFK ERCTQCAAVS WGLTDEGKYY CTSCHNVTER YQEVTNTDLI PNTQIKALNR 
        70         80         90        100        110        120 
GLKKKNNTEK GWDWYVCEGF QYILYQQAEA LKNLGVGPEL KNDVLHNFWK RYLQKSKQAY 
       130        140        150        160        170        180 
CKNPVYTTGR KPTVLEDNLS HSDWASEPEL LSDVSCPPFL ESGAESQSDI HTRKPFPVSK 
       190        200        210        220        230        240 
ASQSETSVCS GSLDGVEYSQ RKEKGIVKMT MPQTLAFCYL SLLWQREAIT LSDLLRFVEE 
       250        260        270        280        290        300 
DHIPYINAFQ HFPEQMKLYG RDRGIFGIES WPDYEDIYKK TVEVGTFLDL PRFPDITEDC 
       310        320        330        340        350        360 
YLHPNILCMK YLMEVNLPDE MHSLTCHVVK MTGMGEVDFL TFDPIAKMAK TVKYDVQAVA 
       370        380        390        400        410        420 
IIVVVLKLLF LLDDSFEWSL SNLAEKHNEK NKKDKPWFDF RKWYQIMKKA FDEKKQKWEE 
       430        440        450        460        470        480 
ARAKYLWKSE KPLYYSFVDK PVAYKKREMV VNLQKQFSTL VESTATAGKK SPSSFQFNWT 
       490        500        510        520        530        540 
EEDTDRTCFH GHSLQGVLKE KGQSLLTKNS LYWLSTQKFC RCYCTHVTTY EESNYSLSYQ 
       550        560        570        580    
FILNLFSFLL RIKTSLLHEE VSLVEKKLFE KKYSVKRKKS RSKKVRRH         10         20         30         40         50         60 
MDLEEAEEFK ERCTQCAAVS WGLTDEGKYY CTSCHNVTER YQEVTNTDLI PNTQIKALNR 
        70         80         90        100        110        120 
GLKKKNNTEK GWDWYVCEGF QYILYQQAEA LKNLGVGPEL KNDVLHNFWK RYLQKSKQAY 
       130        140        150        160        170        180 
CKNPVYTTGR KPTVLEDNLS HSDWASEPEL LSDVSCPPFL ESGAESQSDI HTRKPFPVSK 
       190        200        210        220        230        240 
ASQSETSVCS GSLDGVEYSQ RKEKGIVKMT MPQTLAFCYL SLLWQREAIT LSDLLRFVEE 
       250        260        270        280        290        300 
DHIPYINAFQ HFPEQMKLYG RDRGIFGIES WPDYEDIYKK TVEVGTFLDL PRFPDITEDC 
       310        320        330        340        350        360 
YLHPNILCMK YLMEVNLPDE MHSLTCHVVK MTGMGEVDFL TFDPIAKMAK TVKYDVQAVA 
       370        380        390        400        410        420 
IIVVVLKLLF LLDDSFEWSL SNLAEKHNEK NKKDKPWFDF RKWYQIMKKA FDEKKQKWEE 
       430        440        450        460        470        480 
ARAKYLWKSE KPLYYSFVDK PVAYKKREMV VNLQKQFSTL VESTATAGKK SPSSFQFNWT 
       490        500        510        520        530        540 
EEDTDRTCFH GHSLQGVLKE KGQSLLTKNS LYWLSTQKFC RCYCTHVTTY EESNYSLSYQ 
       550        560        570        580    
FILNLFSFLL RIKTSLLHEE VSLVEKKLFE KKYSVKRKKS RSKKVRRH



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q53T94-1-Acetylation MDLEEA... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q53T94-1-Acetylation MDLEEA... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103530
    Q53T94-1-unknown MDLEEA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91443
    Q53T94-256-unknown MKLYGR... 256 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91444
    Q53T94-256-unknown MKLYGR... 256 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt98792

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)