TopFIND 4.0

Q562D6: tRNA (adenine(37)-N6)-methyltransferase

General Information

Protein names
- tRNA (adenine(37)-N6)-methyltransferase
- 2.1.1.- {ECO:0000250|UniProtKB:Q9BU70}
- tRNA methyltransferase O {ECO:0000312|MGI:MGI:1922003}
Gene names Nap1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q562D6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRGLEKQGSC ATAAPCGCVQ PALEAGNLLT EPIGYLESCF PAKIGTPRQP SICSHSRACL 
        70         80         90        100        110        120 
KIRKNIFNNP EHSLMGLEEF SHVWILFVFH KNGHLNYKAK VQPPRLNGAK TGVFSTRSPH 
       130        140        150        160        170        180 
RPNAIGLTLA KLEKVEGGAV YLSGVDMIDG TPVLDIKPYI ADYDSPQNLS VHNDHHKLRA 
       190        200        210        220        230        240 
EAQVDGTANS CDQLLLSGRG KVQPRQSTKE RPKCLEDRTS GENSQKSRDM SEIQHTLPED 
       250        260        270        280        290        300 
RERALDLALE PSRGESMDMP ENQLGPPELK SFLEEGTDRP RKVEGALVLP GSSAETQWDA 
       310        320        330        340        350        360 
SYRARTADRV PYSVVPSWVT EAPVAPLQVR FTPHAEMDLR KLNSGDASQP SFKYFHSAEE 
       370        380        390        400        410        420 
AKRAIEAVLS ADPRSVYRRK LCEDRLFFFT VDTAHVTCWF GDGFAEVVRI KLASESVQVA 
       430    
DPEESLAALG S

Isoforms

- Isoform 2 of Nef-associated protein 1 - Isoform 3 of Nef-associated protein 1 - Isoform 2 of tRNA (adenine(37)-N6)-methyltransferase - Isoform 3 of tRNA (adenine(37)-N6)-methyltransferase

Sequence View

        10         20         30         40         50         60 
MRGLEKQGSC ATAAPCGCVQ PALEAGNLLT EPIGYLESCF PAKIGTPRQP SICSHSRACL 
        70         80         90        100        110        120 
KIRKNIFNNP EHSLMGLEEF SHVWILFVFH KNGHLNYKAK VQPPRLNGAK TGVFSTRSPH 
       130        140        150        160        170        180 
RPNAIGLTLA KLEKVEGGAV YLSGVDMIDG TPVLDIKPYI ADYDSPQNLS VHNDHHKLRA 
       190        200        210        220        230        240 
EAQVDGTANS CDQLLLSGRG KVQPRQSTKE RPKCLEDRTS GENSQKSRDM SEIQHTLPED 
       250        260        270        280        290        300 
RERALDLALE PSRGESMDMP ENQLGPPELK SFLEEGTDRP RKVEGALVLP GSSAETQWDA 
       310        320        330        340        350        360 
SYRARTADRV PYSVVPSWVT EAPVAPLQVR FTPHAEMDLR KLNSGDASQP SFKYFHSAEE 
       370        380        390        400        410        420 
AKRAIEAVLS ADPRSVYRRK LCEDRLFFFT VDTAHVTCWF GDGFAEVVRI KLASESVQVA 
       430    
DPEESLAALG S         10         20         30         40         50         60 
MRGLEKQGSC ATAAPCGCVQ PALEAGNLLT EPIGYLESCF PAKIGTPRQP SICSHSRACL 
        70         80         90        100        110        120 
KIRKNIFNNP EHSLMGLEEF SHVWILFVFH KNGHLNYKAK VQPPRLNGAK TGVFSTRSPH 
       130        140        150        160        170        180 
RPNAIGLTLA KLEKVEGGAV YLSGVDMIDG TPVLDIKPYI ADYDSPQNLS VHNDHHKLRA 
       190        200        210        220        230        240 
EAQVDGTANS CDQLLLSGRG KVQPRQSTKE RPKCLEDRTS GENSQKSRDM SEIQHTLPED 
       250        260        270        280        290        300 
RERALDLALE PSRGESMDMP ENQLGPPELK SFLEEGTDRP RKVEGALVLP GSSAETQWDA 
       310        320        330        340        350        360 
SYRARTADRV PYSVVPSWVT EAPVAPLQVR FTPHAEMDLR KLNSGDASQP SFKYFHSAEE 
       370        380        390        400        410        420 
AKRAIEAVLS ADPRSVYRRK LCEDRLFFFT VDTAHVTCWF GDGFAEVVRI KLASESVQVA 
       430    
DPEESLAALG S         10         20         30         40         50         60 
MRGLEKQGSC ATAAPCGCVQ PALEAGNLLT EPIGYLESCF PAKIGTPRQP SICSHSRACL 
        70         80         90        100        110        120 
KIRKNIFNNP EHSLMGLEEF SHVWILFVFH KNGHLNYKAK VQPPRLNGAK TGVFSTRSPH 
       130        140        150        160        170        180 
RPNAIGLTLA KLEKVEGGAV YLSGVDMIDG TPVLDIKPYI ADYDSPQNLS VHNDHHKLRA 
       190        200        210        220        230        240 
EAQVDGTANS CDQLLLSGRG KVQPRQSTKE RPKCLEDRTS GENSQKSRDM SEIQHTLPED 
       250        260        270        280        290        300 
RERALDLALE PSRGESMDMP ENQLGPPELK SFLEEGTDRP RKVEGALVLP GSSAETQWDA 
       310        320        330        340        350        360 
SYRARTADRV PYSVVPSWVT EAPVAPLQVR FTPHAEMDLR KLNSGDASQP SFKYFHSAEE 
       370        380        390        400        410        420 
AKRAIEAVLS ADPRSVYRRK LCEDRLFFFT VDTAHVTCWF GDGFAEVVRI KLASESVQVA 
       430    
DPEESLAALG S         10         20         30         40         50         60 
MRGLEKQGSC ATAAPCGCVQ PALEAGNLLT EPIGYLESCF PAKIGTPRQP SICSHSRACL 
        70         80         90        100        110        120 
KIRKNIFNNP EHSLMGLEEF SHVWILFVFH KNGHLNYKAK VQPPRLNGAK TGVFSTRSPH 
       130        140        150        160        170        180 
RPNAIGLTLA KLEKVEGGAV YLSGVDMIDG TPVLDIKPYI ADYDSPQNLS VHNDHHKLRA 
       190        200        210        220        230        240 
EAQVDGTANS CDQLLLSGRG KVQPRQSTKE RPKCLEDRTS GENSQKSRDM SEIQHTLPED 
       250        260        270        280        290        300 
RERALDLALE PSRGESMDMP ENQLGPPELK SFLEEGTDRP RKVEGALVLP GSSAETQWDA 
       310        320        330        340        350        360 
SYRARTADRV PYSVVPSWVT EAPVAPLQVR FTPHAEMDLR KLNSGDASQP SFKYFHSAEE 
       370        380        390        400        410        420 
AKRAIEAVLS ADPRSVYRRK LCEDRLFFFT VDTAHVTCWF GDGFAEVVRI KLASESVQVA 
       430    
DPEESLAALG S



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q562D6-1-unknown MRGLEK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q562D6-1-unknown MRGLEK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82276

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AALGS 431 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AALGS 431 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77895

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)