TopFIND 4.0

Q5BKR2: Sodium/hydrogen exchanger 9B2

General Information

Protein names
- Sodium/hydrogen exchanger 9B2
- NHA-oc {ECO:0000303|PubMed:17988971}
- Na(+)/H(+) exchanger NHA2
- Na(+)/H(+) exchanger-like domain-containing protein 2
- NHE domain-containing protein 2
- Soditlum/hydrogen exchanger-like domain-containing protein 2
- Solute carrier family 9 subfamily B member 2
Gene names Slc9b2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q5BKR2

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEDEDKTAEC QHSKPPTGIT HEAPPHHELQ EERVMSLRGT DRSEPTEGSN LLTSGEKKPQ 
        70         80         90        100        110        120 
DSPTEPNGLQ SLRRFLACPP RGCLARVITN GTMVVLLWAM VWSVTGPECL PGGNLFGIII 
       130        140        150        160        170        180 
LFYCSITGGK LFGLIKFPTL PPLPPLLGML LAGFLLRNIP VINDSVRIQH KWSSSLRSIA 
       190        200        210        220        230        240 
LSVILVRAGL GLDSKALRKL KGVCVRLAMG PCIVEACASA ILSHFLMGLP WQWGFILGFV 
       250        260        270        280        290        300 
VGAVSPAVVV PSMLLLQEGG YGVGKGIPTL LMAAGSFDDI LAITGFNTCL GVAFSTGSTV 
       310        320        330        340        350        360 
FNIFRGILEV VIGVAAGSFL GFFIQYFPSR DQDNLVWKRA FLVLGFAVLA VFSSVYFSFP 
       370        380        390        400        410        420 
GSGGLCTLVM AFLAGMRWTD KKSEVEKVIA VTWDVFQPLL FGLIGAEVSI VSLRAETVGL 
       430        440        450        460        470        480 
CVATLSIAVL IRILTTFLMV CFAGFNIKEK IFISFAWLPK ATVQAAIGSV ALDTARSHGE 
       490        500        510        520        530        540 
KQLEDYGMDV LTVAFLAILI TAPIGSLLIG LLGPRVLQKS EHRTEEEVQG ETSAHIQRKP 
   
EDSITEA

Isoforms

- Isoform 2 of Mitochondrial sodium/hydrogen exchanger 9B2 - Isoform 3 of Mitochondrial sodium/hydrogen exchanger 9B2 - Isoform 2 of Sodium/hydrogen exchanger 9B2 - Isoform 3 of Sodium/hydrogen exchanger 9B2

Sequence View

        10         20         30         40         50         60 
MEDEDKTAEC QHSKPPTGIT HEAPPHHELQ EERVMSLRGT DRSEPTEGSN LLTSGEKKPQ 
        70         80         90        100        110        120 
DSPTEPNGLQ SLRRFLACPP RGCLARVITN GTMVVLLWAM VWSVTGPECL PGGNLFGIII 
       130        140        150        160        170        180 
LFYCSITGGK LFGLIKFPTL PPLPPLLGML LAGFLLRNIP VINDSVRIQH KWSSSLRSIA 
       190        200        210        220        230        240 
LSVILVRAGL GLDSKALRKL KGVCVRLAMG PCIVEACASA ILSHFLMGLP WQWGFILGFV 
       250        260        270        280        290        300 
VGAVSPAVVV PSMLLLQEGG YGVGKGIPTL LMAAGSFDDI LAITGFNTCL GVAFSTGSTV 
       310        320        330        340        350        360 
FNIFRGILEV VIGVAAGSFL GFFIQYFPSR DQDNLVWKRA FLVLGFAVLA VFSSVYFSFP 
       370        380        390        400        410        420 
GSGGLCTLVM AFLAGMRWTD KKSEVEKVIA VTWDVFQPLL FGLIGAEVSI VSLRAETVGL 
       430        440        450        460        470        480 
CVATLSIAVL IRILTTFLMV CFAGFNIKEK IFISFAWLPK ATVQAAIGSV ALDTARSHGE 
       490        500        510        520        530        540 
KQLEDYGMDV LTVAFLAILI TAPIGSLLIG LLGPRVLQKS EHRTEEEVQG ETSAHIQRKP 
   
EDSITEA         10         20         30         40         50         60 
MEDEDKTAEC QHSKPPTGIT HEAPPHHELQ EERVMSLRGT DRSEPTEGSN LLTSGEKKPQ 
        70         80         90        100        110        120 
DSPTEPNGLQ SLRRFLACPP RGCLARVITN GTMVVLLWAM VWSVTGPECL PGGNLFGIII 
       130        140        150        160        170        180 
LFYCSITGGK LFGLIKFPTL PPLPPLLGML LAGFLLRNIP VINDSVRIQH KWSSSLRSIA 
       190        200        210        220        230        240 
LSVILVRAGL GLDSKALRKL KGVCVRLAMG PCIVEACASA ILSHFLMGLP WQWGFILGFV 
       250        260        270        280        290        300 
VGAVSPAVVV PSMLLLQEGG YGVGKGIPTL LMAAGSFDDI LAITGFNTCL GVAFSTGSTV 
       310        320        330        340        350        360 
FNIFRGILEV VIGVAAGSFL GFFIQYFPSR DQDNLVWKRA FLVLGFAVLA VFSSVYFSFP 
       370        380        390        400        410        420 
GSGGLCTLVM AFLAGMRWTD KKSEVEKVIA VTWDVFQPLL FGLIGAEVSI VSLRAETVGL 
       430        440        450        460        470        480 
CVATLSIAVL IRILTTFLMV CFAGFNIKEK IFISFAWLPK ATVQAAIGSV ALDTARSHGE 
       490        500        510        520        530        540 
KQLEDYGMDV LTVAFLAILI TAPIGSLLIG LLGPRVLQKS EHRTEEEVQG ETSAHIQRKP 
   
EDSITEA         10         20         30         40         50         60 
MEDEDKTAEC QHSKPPTGIT HEAPPHHELQ EERVMSLRGT DRSEPTEGSN LLTSGEKKPQ 
        70         80         90        100        110        120 
DSPTEPNGLQ SLRRFLACPP RGCLARVITN GTMVVLLWAM VWSVTGPECL PGGNLFGIII 
       130        140        150        160        170        180 
LFYCSITGGK LFGLIKFPTL PPLPPLLGML LAGFLLRNIP VINDSVRIQH KWSSSLRSIA 
       190        200        210        220        230        240 
LSVILVRAGL GLDSKALRKL KGVCVRLAMG PCIVEACASA ILSHFLMGLP WQWGFILGFV 
       250        260        270        280        290        300 
VGAVSPAVVV PSMLLLQEGG YGVGKGIPTL LMAAGSFDDI LAITGFNTCL GVAFSTGSTV 
       310        320        330        340        350        360 
FNIFRGILEV VIGVAAGSFL GFFIQYFPSR DQDNLVWKRA FLVLGFAVLA VFSSVYFSFP 
       370        380        390        400        410        420 
GSGGLCTLVM AFLAGMRWTD KKSEVEKVIA VTWDVFQPLL FGLIGAEVSI VSLRAETVGL 
       430        440        450        460        470        480 
CVATLSIAVL IRILTTFLMV CFAGFNIKEK IFISFAWLPK ATVQAAIGSV ALDTARSHGE 
       490        500        510        520        530        540 
KQLEDYGMDV LTVAFLAILI TAPIGSLLIG LLGPRVLQKS EHRTEEEVQG ETSAHIQRKP 
   
EDSITEA         10         20         30         40         50         60 
MEDEDKTAEC QHSKPPTGIT HEAPPHHELQ EERVMSLRGT DRSEPTEGSN LLTSGEKKPQ 
        70         80         90        100        110        120 
DSPTEPNGLQ SLRRFLACPP RGCLARVITN GTMVVLLWAM VWSVTGPECL PGGNLFGIII 
       130        140        150        160        170        180 
LFYCSITGGK LFGLIKFPTL PPLPPLLGML LAGFLLRNIP VINDSVRIQH KWSSSLRSIA 
       190        200        210        220        230        240 
LSVILVRAGL GLDSKALRKL KGVCVRLAMG PCIVEACASA ILSHFLMGLP WQWGFILGFV 
       250        260        270        280        290        300 
VGAVSPAVVV PSMLLLQEGG YGVGKGIPTL LMAAGSFDDI LAITGFNTCL GVAFSTGSTV 
       310        320        330        340        350        360 
FNIFRGILEV VIGVAAGSFL GFFIQYFPSR DQDNLVWKRA FLVLGFAVLA VFSSVYFSFP 
       370        380        390        400        410        420 
GSGGLCTLVM AFLAGMRWTD KKSEVEKVIA VTWDVFQPLL FGLIGAEVSI VSLRAETVGL 
       430        440        450        460        470        480 
CVATLSIAVL IRILTTFLMV CFAGFNIKEK IFISFAWLPK ATVQAAIGSV ALDTARSHGE 
       490        500        510        520        530        540 
KQLEDYGMDV LTVAFLAILI TAPIGSLLIG LLGPRVLQKS EHRTEEEVQG ETSAHIQRKP 
   
EDSITEA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5BKR2-1-unknown MEDEDK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5BKR2-253-unknown MLLLQE... 253 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89894
    Q5BKR2-439-unknown MVCFAG... 439 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89895
    Q5BKR2-439-unknown MVCFAG... 439 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt98095

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)