Q5DW34: Histone-lysine N-methyltransferase EHMT1

General Information

Protein names	- Histone-lysine N-methyltransferase EHMT1 - 2.1.1.- - 2.1.1.43 - Euchromatic histone-lysine N-methyltransferase 1 - Eu-HMTase1 - G9a-like protein 1 - GLP - GLP1 - Lysine N-methyltransferase 1D
Gene names	Ehmt1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5DW34

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAADAEQAV LAKQETKQDC CMKTELLRED TPMAADEGST EKQEGETPMA ADGETNGSCE
        70         80         90        100        110        120
KSGDPSHLNA PKHTQENTRA SPQEGTNRVS RVAENGVSER DTEVGKQNHV TADDFMQTSV
       130        140        150        160        170        180
IGSNGYFLNK PALQGQPLRT PNILTSSLPG HAAKTLPGGA SKCRTLSALP QTPTTAPTVP
       190        200        210        220        230        240
GEGSADTEDR KPTASGTDVR VHRARKTMPK SILGLHAASK DHREVQDHKE PKEDINRNIS
       250        260        270        280        290        300
ECGRQQLLPT FPALHQSLPQ NQCYMATTKS QTACLPFVLA AAVSRKKKRR MGTYSLVPKK
       310        320        330        340        350        360
KTKVLKQRTV IEMFKSITHS TVGAKGEKAL DDSALHVNGE SLEMDSEDED SDELEDDEDH
       370        380        390        400        410        420
GAEQAAAFPT EDSRTSKESM SETDRAAKMD GDSEEEQESP DTGEDEDGGD ESDLSSESSI
       430        440        450        460        470        480
KKKFLKRRGK TDSPWIKPAR KRRRRSRKKP SSMLGSEACK SSPGSMEQAA LGDSAGYMEV
       490        500        510        520        530        540
SLDSLDLRVR GILSSQTENE GLASGPDVLG TDGLQEVPLC SCRMETPKSR EISTLANNQC
       550        560        570        580        590        600
MATESVDHEL GRCTNSVVKY ELMRPSNKAP LLVLCEDHRG RMVKHQCCPG CGYFCTAGNF
       610        620        630        640        650        660
MECQPESSIS HRFHKDCASR VNNASYCPHC GEEASKAKEV TIAKADTTST VTLAPGQEKS
       670        680        690        700        710        720
LAAEGRADTT TGSIAGAPED ERSQSTAPQA PECFDPAGPA GLVRPTSGLS QGPGKETLES
       730        740        750        760        770        780
ALIALDSEKP KKLRFHPKQL YFSARQGELQ KVLLMLVDGI DPNFKMEHQS KRSPLHAAAE
       790        800        810        820        830        840
AGHVDICHML VQAGANIDTC SEDQRTPLME AAENNHLDAV KYLIKAGAQV DPKDAEGSTC
       850        860        870        880        890        900
LHLAAKKGHY DVVQYLLSNG QMDVNCQDDG GWTPMIWATE YKHVELVKLL LSKGSDINIR
       910        920        930        940        950        960
DNEENICLHW AAFSGCVDIA EILLAAKCDL HAVNIHGDSP LHIAARENRY DCVVLFLSRD
       970        980        990       1000       1010       1020
SDVTLKNKEG ETPLQCASLS SQVWSALQMS KALRDSAPDK PVAVEKTVSR DIARGYERIP
      1030       1040       1050       1060       1070       1080
IPCVNAVDSE LCPTNYKYVS QNCVTSPMNI DRNITHLQYC VCVDDCSSST CMCGQLSMRC
      1090       1100       1110       1120       1130       1140
WYDKDGRLLP EFNMAEPPLI FECNHACSCW RNCRNRVVQN GLRARLQLYR TQDMGWGVRS
      1150       1160       1170       1180       1190       1200
LQDIPLGTFV CEYVGELISD SEADVREEDS YLFDLDNKDG EVYCIDARFY GNVSRFINHH
      1210       1220       1230       1240       1250       1260
CEPNLVPVRV FMSHQDLRFP RIAFFSTRLI QAGEQLGFDY GERFWDVKGK LFSCRCGSSK
      1270       1280       1290
CRHSSAALAQ RQASAAQEPQ ENGLPDTSSA AAADPL

Isoforms

- Isoform 2 of Histone-lysine N-methyltransferase EHMT1 - Isoform 3 of Histone-lysine N-methyltransferase EHMT1

Sequence View

        10         20         30         40         50         60
MAAADAEQAV LAKQETKQDC CMKTELLRED TPMAADEGST EKQEGETPMA ADGETNGSCE
        70         80         90        100        110        120
KSGDPSHLNA PKHTQENTRA SPQEGTNRVS RVAENGVSER DTEVGKQNHV TADDFMQTSV
       130        140        150        160        170        180
IGSNGYFLNK PALQGQPLRT PNILTSSLPG HAAKTLPGGA SKCRTLSALP QTPTTAPTVP
       190        200        210        220        230        240
GEGSADTEDR KPTASGTDVR VHRARKTMPK SILGLHAASK DHREVQDHKE PKEDINRNIS
       250        260        270        280        290        300
ECGRQQLLPT FPALHQSLPQ NQCYMATTKS QTACLPFVLA AAVSRKKKRR MGTYSLVPKK
       310        320        330        340        350        360
KTKVLKQRTV IEMFKSITHS TVGAKGEKAL DDSALHVNGE SLEMDSEDED SDELEDDEDH
       370        380        390        400        410        420
GAEQAAAFPT EDSRTSKESM SETDRAAKMD GDSEEEQESP DTGEDEDGGD ESDLSSESSI
       430        440        450        460        470        480
KKKFLKRRGK TDSPWIKPAR KRRRRSRKKP SSMLGSEACK SSPGSMEQAA LGDSAGYMEV
       490        500        510        520        530        540
SLDSLDLRVR GILSSQTENE GLASGPDVLG TDGLQEVPLC SCRMETPKSR EISTLANNQC
       550        560        570        580        590        600
MATESVDHEL GRCTNSVVKY ELMRPSNKAP LLVLCEDHRG RMVKHQCCPG CGYFCTAGNF
       610        620        630        640        650        660
MECQPESSIS HRFHKDCASR VNNASYCPHC GEEASKAKEV TIAKADTTST VTLAPGQEKS
       670        680        690        700        710        720
LAAEGRADTT TGSIAGAPED ERSQSTAPQA PECFDPAGPA GLVRPTSGLS QGPGKETLES
       730        740        750        760        770        780
ALIALDSEKP KKLRFHPKQL YFSARQGELQ KVLLMLVDGI DPNFKMEHQS KRSPLHAAAE
       790        800        810        820        830        840
AGHVDICHML VQAGANIDTC SEDQRTPLME AAENNHLDAV KYLIKAGAQV DPKDAEGSTC
       850        860        870        880        890        900
LHLAAKKGHY DVVQYLLSNG QMDVNCQDDG GWTPMIWATE YKHVELVKLL LSKGSDINIR
       910        920        930        940        950        960
DNEENICLHW AAFSGCVDIA EILLAAKCDL HAVNIHGDSP LHIAARENRY DCVVLFLSRD
       970        980        990       1000       1010       1020
SDVTLKNKEG ETPLQCASLS SQVWSALQMS KALRDSAPDK PVAVEKTVSR DIARGYERIP
      1030       1040       1050       1060       1070       1080
IPCVNAVDSE LCPTNYKYVS QNCVTSPMNI DRNITHLQYC VCVDDCSSST CMCGQLSMRC
      1090       1100       1110       1120       1130       1140
WYDKDGRLLP EFNMAEPPLI FECNHACSCW RNCRNRVVQN GLRARLQLYR TQDMGWGVRS
      1150       1160       1170       1180       1190       1200
LQDIPLGTFV CEYVGELISD SEADVREEDS YLFDLDNKDG EVYCIDARFY GNVSRFINHH
      1210       1220       1230       1240       1250       1260
CEPNLVPVRV FMSHQDLRFP RIAFFSTRLI QAGEQLGFDY GERFWDVKGK LFSCRCGSSK
      1270       1280       1290
CRHSSAALAQ RQASAAQEPQ ENGLPDTSSA AAADPL         10         20         30         40         50         60
MAAADAEQAV LAKQETKQDC CMKTELLRED TPMAADEGST EKQEGETPMA ADGETNGSCE
        70         80         90        100        110        120
KSGDPSHLNA PKHTQENTRA SPQEGTNRVS RVAENGVSER DTEVGKQNHV TADDFMQTSV
       130        140        150        160        170        180
IGSNGYFLNK PALQGQPLRT PNILTSSLPG HAAKTLPGGA SKCRTLSALP QTPTTAPTVP
       190        200        210        220        230        240
GEGSADTEDR KPTASGTDVR VHRARKTMPK SILGLHAASK DHREVQDHKE PKEDINRNIS
       250        260        270        280        290        300
ECGRQQLLPT FPALHQSLPQ NQCYMATTKS QTACLPFVLA AAVSRKKKRR MGTYSLVPKK
       310        320        330        340        350        360
KTKVLKQRTV IEMFKSITHS TVGAKGEKAL DDSALHVNGE SLEMDSEDED SDELEDDEDH
       370        380        390        400        410        420
GAEQAAAFPT EDSRTSKESM SETDRAAKMD GDSEEEQESP DTGEDEDGGD ESDLSSESSI
       430        440        450        460        470        480
KKKFLKRRGK TDSPWIKPAR KRRRRSRKKP SSMLGSEACK SSPGSMEQAA LGDSAGYMEV
       490        500        510        520        530        540
SLDSLDLRVR GILSSQTENE GLASGPDVLG TDGLQEVPLC SCRMETPKSR EISTLANNQC
       550        560        570        580        590        600
MATESVDHEL GRCTNSVVKY ELMRPSNKAP LLVLCEDHRG RMVKHQCCPG CGYFCTAGNF
       610        620        630        640        650        660
MECQPESSIS HRFHKDCASR VNNASYCPHC GEEASKAKEV TIAKADTTST VTLAPGQEKS
       670        680        690        700        710        720
LAAEGRADTT TGSIAGAPED ERSQSTAPQA PECFDPAGPA GLVRPTSGLS QGPGKETLES
       730        740        750        760        770        780
ALIALDSEKP KKLRFHPKQL YFSARQGELQ KVLLMLVDGI DPNFKMEHQS KRSPLHAAAE
       790        800        810        820        830        840
AGHVDICHML VQAGANIDTC SEDQRTPLME AAENNHLDAV KYLIKAGAQV DPKDAEGSTC
       850        860        870        880        890        900
LHLAAKKGHY DVVQYLLSNG QMDVNCQDDG GWTPMIWATE YKHVELVKLL LSKGSDINIR
       910        920        930        940        950        960
DNEENICLHW AAFSGCVDIA EILLAAKCDL HAVNIHGDSP LHIAARENRY DCVVLFLSRD
       970        980        990       1000       1010       1020
SDVTLKNKEG ETPLQCASLS SQVWSALQMS KALRDSAPDK PVAVEKTVSR DIARGYERIP
      1030       1040       1050       1060       1070       1080
IPCVNAVDSE LCPTNYKYVS QNCVTSPMNI DRNITHLQYC VCVDDCSSST CMCGQLSMRC
      1090       1100       1110       1120       1130       1140
WYDKDGRLLP EFNMAEPPLI FECNHACSCW RNCRNRVVQN GLRARLQLYR TQDMGWGVRS
      1150       1160       1170       1180       1190       1200
LQDIPLGTFV CEYVGELISD SEADVREEDS YLFDLDNKDG EVYCIDARFY GNVSRFINHH
      1210       1220       1230       1240       1250       1260
CEPNLVPVRV FMSHQDLRFP RIAFFSTRLI QAGEQLGFDY GERFWDVKGK LFSCRCGSSK
      1270       1280       1290
CRHSSAALAQ RQASAAQEPQ ENGLPDTSSA AAADPL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5DW34-1-unknown	MAAADA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5DW34-1-unknown	MAAADA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73749
Q5DW34-1-unknown	MAAADA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73750
Q5DW34-89-unknown	VSRVAE...	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119057
Q5DW34-89-unknown	VSRVAE...	89	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196775
Q5DW34-89-unknown	VSRVAE...	89	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196776

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AAAVSR	284	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123187
...DHGAEQ	363	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119854
...VPLCSC	521	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123387
...AADPL	1296	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AADPL	1296	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69367
...AADPL	1296	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69368

TopFIND

Q5DW34: Histone-lysine N-methyltransferase EHMT1

General Information

2

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates